sp2-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo

Autor: Schaeffer, Evelyne, Sánchez-Fernández, Elena M., Gonçalves-Pereira, Rita, Flacher, Vincent, Lamon, Delphine, Duval, Monique, Fauny, Jean-Daniel, García Fernández, José M., Mueller, Christopher G., Ortiz Mellet, Carmen

Publikováno v: In European Journal of Medicinal Chemistry 1 May 2019 169:111-120

Severe combined immunodeficiency in Sting V154M/WT mice

Autor: Bouis, Delphine, Kirstetter, Peggy, Arbogast, Florent, Lamon, Delphine, Delgado, Virginia, Jung, Sophie, Ebel, Claudine, Jacobs, Hugues, Knapp, Anne-Marie, Jeremiah, Nadia, Belot, Alexandre, Martin, Thierry, Crow, Yanick J, André-Schmutz, Isabelle, Korganow, Anne-Sophie, Rieux-Laucat, Frédéric, Soulas-Sprauel, Pauline

Publikováno v: Bouis, D, Kirstetter, P, Arbogast, F, Lamon, D, Delgado, V, Jung, S, Ebel, C, Jacobs, H, Knapp, A-M, Jeremiah, N, Belot, A, Martin, T, Crow, Y J, André-Schmutz, I, Korganow, A-S, Rieux-Laucat, F & Soulas-Sprauel, P 2018, ' Severe combined immunodeficiency in Sting V154M/WT mice ', Journal of Allergy and Clinical Immunology . https://doi.org/10.1016/j.jaci.2018.04.034

BACKGROUND: Autosomal dominant gain-of-function (GOF) mutations in human STING (Stimulator of Interferon Genes) lead to a severe autoinflammatory disease called SAVI (STING Associated Vasculopathy with onset in Infancy), associated with enhanced expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::98bcb99d71f6bc5330fece152ba1c1d5
https://www.pure.ed.ac.uk/ws/files/77202135/Article_Sting_mice_06.10.17_YJC_AAM.docx

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Overexpression of Fkbp11, a feature of lupus B cells, leads to B cell tolerance breakdown and initiates plasma cell differentiation.

Autor: Ruer‐Laventie, Julie, Simoni, Léa, Schickel, Jean‐Nicolas, Soley, Anne, Duval, Monique, Knapp, Anne‐Marie, Marcellin, Luc, Lamon, Delphine, Korganow, Anne‐Sophie, Martin, Thierry, Pasquali, Jean‐Louis, Soulas‐Sprauel, Pauline

Publikováno v: Immunity, Inflammation & Disease; Sep2015, Vol. 3 Issue 3, p265-279, 15p