Optogenetic dissection of transcriptional repression in a multicellular organism.

Autor: Zhao J; Department of Physics, University of California, Berkeley, CA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Lammers NC; Biophysics Graduate Group, University of California, Berkeley, CA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Alamos S; Department of Plant and Microbial Biology, University of California, Berkeley, CA, USA.; Feedstocks Division, Joint BioEnergy Institute, Emeryville, CA, USA.; Environmental Genomics and Systems Biology Division, LBNL, Berkeley, CA, USA., Kim YJ; Biophysics Graduate Group, University of California, Berkeley, CA, USA., Martini G; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Garcia HG; Department of Physics, University of California, Berkeley, CA, USA. hggarcia@berkeley.edu.; Biophysics Graduate Group, University of California, Berkeley, CA, USA. hggarcia@berkeley.edu.; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. hggarcia@berkeley.edu.; Institute for Quantitative Biosciences-QB3, University of California, Berkeley, CA, USA. hggarcia@berkeley.edu.; Chan Zuckerberg Biohub, San Francisco, CA, USA. hggarcia@berkeley.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Oct 26; Vol. 15 (1), pp. 9263. Date of Electronic Publication: 2024 Oct 26.

Optogenetic control of YAP reveals a dynamic communication code for stem cell fate and proliferation.

Autor: Meyer K; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA., Lammers NC; Biophysics Graduate Group, University of California at Berkeley, Berkeley, CA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Bugaj LJ; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA., Garcia HG; Biophysics Graduate Group, University of California at Berkeley, Berkeley, CA, USA.; Department of Physics, University of California at Berkeley, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.; Institute for Quantitative Biosciences-QB3, University of California at Berkeley, Berkeley, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Weiner OD; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA. orion.weiner@ucsf.edu.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA. orion.weiner@ucsf.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Oct 30; Vol. 14 (1), pp. 6929. Date of Electronic Publication: 2023 Oct 30.

Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila .

Autor: Child MB 6th; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; Department of Physics, University of California, Berkeley, Berkeley, United States., Bateman JR; Biology Department, Bowdoin College, Brunswick, United States., Jahangiri A; Univ Grenoble Alpes CNRS, Grenoble INP, TIMC-IMAG, Grenoble, France., Reimer A; Biophysics Graduate Group, University of California, Berkeley, Berkeley, United States., Lammers NC; Biophysics Graduate Group, University of California, Berkeley, Berkeley, United States., Sabouni N; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States., Villamarin D; Biology Department, Bowdoin College, Brunswick, United States., McKenzie-Smith GC; Biology Department, Bowdoin College, Brunswick, United States., Johnson JE; Biology Department, Bowdoin College, Brunswick, United States., Jost D; Univ Grenoble Alpes CNRS, Grenoble INP, TIMC-IMAG, Grenoble, France.; Université de Lyon, ENS de Lyon, Univ Claude Bernard, CNRS, Laboratory of Biology and Modeling of the Cell, Lyon, France., Garcia HG; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; Department of Physics, University of California, Berkeley, Berkeley, United States.; Biophysics Graduate Group, University of California, Berkeley, Berkeley, United States.; Institute for Quantitative Biosciences-QB3, University of California, Berkeley, Berkeley, United States.

Publikováno v: ELife [Elife] 2021 Jun 08; Vol. 10. Date of Electronic Publication: 2021 Jun 08.

A matter of time: Using dynamics and theory to uncover mechanisms of transcriptional bursting.

Autor: Lammers NC; Biophysics Graduate Group, University of California at Berkeley, Berkeley, CA, USA., Kim YJ; Biophysics Graduate Group, University of California at Berkeley, Berkeley, CA, USA., Zhao J; Department of Physics, University of California at Berkeley, Berkeley, CA, USA., Garcia HG; Biophysics Graduate Group, University of California at Berkeley, Berkeley, CA, USA; Department of Physics, University of California at Berkeley, Berkeley, CA, USA; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA; Institute for Quantitative Biosciences-QB3, University of California at Berkeley, Berkeley, CA, USA. Electronic address: hggarcia@berkeley.edu.

Publikováno v: Current opinion in cell biology [Curr Opin Cell Biol] 2020 Dec; Vol. 67, pp. 147-157. Date of Electronic Publication: 2020 Nov 24.

Enhancer Priming Enables Fast and Sustained Transcriptional Responses to Notch Signaling.

Autor: Falo-Sanjuan J; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK., Lammers NC; Biophysics Graduate Group, UC Berkeley, Berkeley, CA 94720, USA., Garcia HG; Biophysics Graduate Group, UC Berkeley, Berkeley, CA 94720, USA; Department of Physics, UC Berkeley, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, UC Berkeley, Berkeley, CA 94720, USA; Institute for Quantitative Biosciences-QB3, UC Berkeley, Berkeley, CA 94720, USA., Bray SJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK. Electronic address: sjb32@cam.ac.uk.

Publikováno v: Developmental cell [Dev Cell] 2019 Aug 19; Vol. 50 (4), pp. 411-425.e8. Date of Electronic Publication: 2019 Aug 01.