Reverse-Transcriptase Inhibitors in the Aicardi–Goutières Syndrome

Autor: Diana Rodriguez, Vincent Bondet, Alexandre Belot, Luis Seabra, Claude Cances, Isabelle Desguerre, Virginie Levrat, Diane Doummar, Elodie Henry, Marie Hully, Mathieu P Rodero, Isabelle Melki, Magalie Barth, Alba Llibre, Agathe Roubertie, François-Guillaume Debray, Jean-Marc Tréluyer, Michaela Semeraro, Valérie Jolaine, Nathalie Boddaert, Pierre Meyer, Christine Barnerias, Carolina Uggenti, Jinmi Baek, Gillian I. Rice, Flore Rozenberg, Darragh Duffy, Stéphane Blanche, Marie-Louise Frémond, Florence Renaldo, Naïm Bouazza, Hendy Abdoul, Leo A. H. Zeef, Mame N Sambe, Candice Meyzer, Yanick J. Crow, Marie-Christine Nougues, Alice Lepelley, Naoki Kitabayashi

Publikováno v: New England Journal of Medicine
New England Journal of Medicine, 2018, 379 (23), pp.2275-2277. ⟨10.1056/NEJMc1810983⟩
Rice, G I, Meyzer, C, Bouazza, N, Hully, M, Boddaert, N, Semeraro, M, Zeef, L A H, Rozenberg, F, Bondet, V, Duffy, D, Llibre, A, Baek, J, Sambe, M N, Henry, E, Jolaine, V, Barnerias, C, Barth, M, Belot, A, Cances, C, Debray, F-G, Doummar, D, Frémond, M-L, Kitabayashi, N, Lepelley, A, Levrat, V, Melki, I, Meyer, P, Nougues, M-C, Renaldo, F, Rodero, M P, Rodriguez, D, Roubertie, A, Seabra, L, Uggenti, C, Abdoul, H, Treluyer, J-M, Desguerre, I, Blanche, S & Crow, Y J 2018, ' Reverse-Transcriptase Inhibitors in the Aicardi–Goutières Syndrome ', New England Journal of Medicine, vol. 379, no. 23, pp. 2275-7 . https://doi.org/10.1056/NEJMc1810983
New England Journal of Medicine, Massachusetts Medical Society, 2018, 379 (23), pp.2275-2277. ⟨10.1056/NEJMC1810983⟩
New England Journal of Medicine, Massachusetts Medical Society, 2018, 379 (23), pp.2275-2277. ⟨10.1056/NEJMc1810983⟩

International audience; To the Editor:The Aicardi–Goutières syndrome is a genetic encephalopathy that is associated with childhood illness and death. The syndrome is hypothesized to be due to misidentification of self-derived nucleic acids as nons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771251eb6b388f0e1e12dad20dec87f3

HBV genotypes and response to tenofovir disoproxil fumarate in HIV/HBV-coinfected persons

Autor: Florian, Bihl, Gladys, Martinetti, Gilles, Wandeler, Rainer, Weber, Bruno, Ledergeber, Alexandra, Calmy, Manuel, Battegay, Matthias, Cavassini, Pietro, Vernazza, Anna-Paola, Caminada, Martin, Rickenbach, Enos, Bernasconi, S, Yerly

Publikováno v: Bihl, Florian; Martinetti, Gladys; Wandeler, Gilles; Weber, Rainer; Ledergeber, Bruno; Calmy, Alexandra; Battegay, Manuel; Cavassini, Matthias; Vernazza, Pietro; Caminada, Anna-Paola; Rickenbach, Martin; Bernasconi, Enos (2015). HBV genotypes and response to tenofovir disoproxil fumarate in HIV/HBV-coinfected persons. BMC gastroenterology, 15(1), p. 79. BioMed Central 10.1186/s12876-015-0308-0
BMC Gastroenterology
Bmc Gastroenterology, vol. 15, pp. 79

BACKGROUND: Hepatitis B virus (HBV) genotypes can influence treatment outcome in HBV-monoinfected and human immunodeficiency virus (HIV)/HBV-coinfected patients. Tenofovir disoproxil fumarate (TDF) plays a pivotal role in antiretroviral therapy (ART)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f3992329a8aad0c2bae9eeece0c682
https://boris.unibe.ch/70336/1/12876_2015_Article_308.pdf

Persistent production of an integrase-deleted HIV-1 variant with no resistance mutation and wild-type proviral DNA in a treated patient

Autor: Christophe Ramière, Patrice Andre, Fabienne Venet, Mary-Anne Trabaud, Laurent Cotte, Corinne Ronfort, Guillaume Monneret, Jean-Claude Tardy, J. Saison

Publikováno v: AIDS RESEARCH AND HUMAN RETROVIRUSES
AIDS RESEARCH AND HUMAN RETROVIRUSES, 2015, 31 (1), pp.142-9. ⟨10.1089/AID.2014.0129⟩
AIDS Research and Human Retroviruses
AIDS Research and Human Retroviruses, Mary Ann Liebert, 2015, 31 (1), pp.142-149. ⟨10.1089/AID.2014.0129⟩

Supplementary Data; International audience; An HIV-infected patient presenting an unexpected viral escape under combined antiretroviral treatment is described. The virus isolated from plasma contained a large deletion in the HIV-1 integrase gene but

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b1d02fc2d254d3fee0f9883c920d1d
https://hal-univ-lyon1.archives-ouvertes.fr/hal-02192928

Long-Term Follow-Up Study of Chinese Patients with YMDD Mutations: Significance of Hepatitis B Virus Genotypes and Characteristics of Biochemical Flares

Autor: Ching-Lung Lai, He-Jun Yuan, Erwin Sablon, Annie On-On Chan, Man-Fung Yuen, Danny Ka-Ho Wong, Benjamin C.Y. Wong

Publikováno v: Journal of Clinical Microbiology. 42:3932-3936

We sought to examine the role of hepatitis B virus (HBV) genotypes in virological breakthroughs and biochemical flares in patients with YMDD mutations during lamivedine therapy. Virologic breakthroughs (i.e., the reappearance of HBV DNA as determined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729066a3514fe48960166dc699450199
https://doi.org/10.1128/jcm.42.9.3932-3936.2004

Evolution of primary and compensatory lamivudine resistance mutations in chronic hepatitis B virus-infected patients during long-term lamivudine treatment, assessed by a line probe assay

Autor: Joke Doutreloigne, Erwin Sablon, Fred Shapiro, Evelien Libbrecht, Man-Fung Yuen, Ching-Lung Lai, Hilde Van De Velde

Publikováno v: Journal of clinical microbiology. 45(12)

With the availability of more potent nucleotide/nucleoside analogues, the early detection of drug-resistant mutants of hepatitis B virus (HBV) is important for the strategic treatment of chronic hepatitis B. We studied 336 serum samples from 80 patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b5975a7a9f6829b206070e987b9f35
https://pubmed.ncbi.nlm.nih.gov/17913933