Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Lamin B"'
Autor:
Andrew Ayi-Ashong Bruce, Ama-Onyebuchi Umesi, Adedapo Bashorun, Magnus Ochoge, Mohammed Yisa, Dolapo Obayemi-Ajiboye, Ahmed Futa, Anna Njie, Selasi Asase, Modou Bella Jallow, Larry Kotei, Lucy Affleck, Olubunmi Abiola Olubiyi, Lamin B. Jarju, Madi Kanyi, Baba Danso, Armel Zemsi, Ed Clarke
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Despite Africa’s significant infectious disease burden, it is underrepresented in global vaccine clinical trials. While this trend is slowly reversing, it is important to recognize and mitigate the challenges that arise when con
Externí odkaz:
https://doaj.org/article/696eafdb02a2473b9f9ab3cfc47b73dd
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102777- (2024)
Summary: Many immunological treatment strategies for reducing the HIV-1 reservoir and enhancing adaptive immunity aim at activating the human plasmacytoid dendritic cells (pDCs). Here, we present a protocol for pDC enrichment, single-cell analysis, a
Externí odkaz:
https://doaj.org/article/ca16c8b4d1c747feb4d14aca7ab6de69
Autor:
Lamin B. Cham, Jesper D. Gunst, Mariane H. Schleimann, Giacomo S. Frattari, Miriam Rosas-Umbert, Line K. Vibholm, Renée M. van der Sluis, Martin R. Jakobsen, Rikke Olesen, Lin Lin, Martin Tolstrup, Ole S. Søgaard
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107628- (2023)
Summary: Human plasmacytoid dendritic cells (pDCs) play a central role in initiating and activating host immune responses during infection. To understand how the transcriptome of pDCs is impacted by HIV-1 infection and exogenous stimulation, we isola
Externí odkaz:
https://doaj.org/article/c71981a857e54b519eb37f5423105348
Autor:
Ikechukwu Adigweme, Edem Akpalu, Mohammed Yisa, Simon Donkor, Lamin B. Jarju, Baba Danso, Anthony Mendy, David Jeffries, Abdoulie Njie, Andrew Bruce, Michael Royals, James L. Goodson, Mark R. Prausnitz, Devin McAllister, Paul A. Rota, Sebastien Henry, Ed Clarke
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-30 (2022)
Abstract Background New strategies to increase measles and rubella vaccine coverage, particularly in low- and middle-income countries, are needed if elimination goals are to be achieved. With this regard, measles and rubella vaccine microneedle patch
Externí odkaz:
https://doaj.org/article/451b16dbeb754d37932f78c78fc69a68
Autor:
Phyllis F. Cheung, JiaJin Yang, Rui Fang, Arianna Borgers, Kirsten Krengel, Anne Stoffel, Kristina Althoff, Chi Wai Yip, Elaine H. L. Siu, Linda W. C. Ng, Karl S. Lang, Lamin B. Cham, Daniel R. Engel, Camille Soun, Igor Cima, Björn Scheffler, Jana K. Striefler, Marianne Sinn, Marcus Bahra, Uwe Pelzer, Helmut Oettle, Peter Markus, Esther M. M. Smeets, Erik H. J. G. Aarntzen, Konstantinos Savvatakis, Sven-Thorsten Liffers, Smiths S. Lueong, Christian Neander, Anna Bazarna, Xin Zhang, Annette Paschen, Howard C. Crawford, Anthony W. H. Chan, Siu Tim Cheung, Jens T. Siveke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Immune responses to pancreatic ductal adenocarcinoma can be inhibited by cancer cells. Here the authors show that high levels of progranulin in PDAC inhibits immune responses by reducing MHC class I antigen presentation through enhanced degradation o
Externí odkaz:
https://doaj.org/article/c9aa189db2194c2eba13f30f461a6fdd
Autor:
Hilal Bhat, Gregor Zaun, Thamer A. Hamdan, Judith Lang, Tom Adomati, Rosa Schmitz, Sarah-Kim Friedrich, Michael Bergerhausen, Lamin B. Cham, Fanghui Li, Murtaza Ali, Fan Zhou, Vishal Khairnar, Vikas Duhan, Tim Brandenburg, Yara Maria Machlah, Maximilian Schiller, Arshia Berry, Haifeng Xu, Jörg Vollmer, Dieter Häussinger, Beatrice Thier, Aleksandra A. Pandyra, Dirk Schadendorf, Annette Paschen, Martin Schuler, Philipp A. Lang, Karl S. Lang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Immune activation within the tumor microenvironment is one promising approach to induce tumor regression. Certain viruses including oncolytic viruses such as the herpes simplex virus (HSV) and non-oncolytic viruses such as the lymphocytic choriomenin
Externí odkaz:
https://doaj.org/article/75601dc4b0134284b6d488ec8fac6ac6
Autor:
Michal Caspi Tal, Laughing Bear Torrez Dulgeroff, Lara Myers, Lamin B. Cham, Katrin D. Mayer-Barber, Andrea C. Bohrer, Ehydel Castro, Ying Ying Yiu, Cesar Lopez Angel, Ed Pham, Aaron B. Carmody, Ronald J. Messer, Eric Gars, Jens Kortmann, Maxim Markovic, Michaela Hasenkrug, Karin E. Peterson, Clayton W. Winkler, Tyson A. Woods, Paige Hansen, Sarah Galloway, Dhananjay Wagh, Benjamin J. Fram, Thai Nguyen, Daniel Corey, Raja Sab Kalluru, Niaz Banaei, Jayakumar Rajadas, Denise M. Monack, Aijaz Ahmed, Debashis Sahoo, Mark M. Davis, Jeffrey S. Glenn, Tom Adomati, Karl S. Lang, Irving L. Weissman, Kim J. Hasenkrug
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT It is well understood that the adaptive immune response to infectious agents includes a modulating suppressive component as well as an activating component. We now show that the very early innate response also has an immunosuppressive compon
Externí odkaz:
https://doaj.org/article/d8f71f31b4e248b893caeb967d0cb234
Autor:
Tom Adomati, Lamin B. Cham, Thamer A. Hamdan, Hilal Bhat, Vikas Duhan, Fanghui Li, Murtaza Ali, Elisabeth Lang, Anfei Huang, Eyad Naser, Vishal Khairnar, Sarah-Kim Friedrich, Judith Lang, Justa Friebus-Kardash, Michael Bergerhausen, Maximilian Schiller, Yara Maria Machlah, Florian Lang, Dieter Häussinger, Stanislav Ferencik, Cornelia Hardt, Philipp A. Lang, Karl S. Lang
Publikováno v:
Cell Reports, Vol 30, Iss 11, Pp 3671-3681.e5 (2020)
Summary: Infections can result in a temporarily restricted unresponsiveness of the innate immune response, thereby limiting pathogen control. Mechanisms of such unresponsiveness are well studied in lipopolysaccharide tolerance; however, whether mecha
Externí odkaz:
https://doaj.org/article/adb0a8a0b0c54307b1e06bb9c186cfaa
Autor:
Anne L. Wilson, Margaret Pinder, John Bradley, Martin J. Donnelly, Majidah Hamid‑Adiamoh, Lamin B. S. Jarju, Musa Jawara, David Jeffries, Ballah Kandeh, Emily J. Rippon, Kolawole Salami, Umberto D’Alessandro, Steven W. Lindsay
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-5 (2018)
Unfortunately, the original article [1] contained an error mistakenly carried forward by the Production department handling this article whereby some figures and their captions were interchanged. The correct figures (Figs. 1, 2, 3, 4, 5) and captions
Externí odkaz:
https://doaj.org/article/5ac9c2123ada443d8603651edfe095e9
Autor:
Anne L. Wilson, Margaret Pinder, John Bradley, Martin J. Donnelly, Majidah Hamid-Adiamoh, Lamin B. S. Jarju, Musa Jawara, David Jeffries, Ballah Kandeh, Emily J. Rippon, Kolawole Salami, Umberto D’Alessandro, Steven W. Lindsay
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-14 (2018)
Abstract Background Insecticide resistance threatens malaria control in sub-Saharan Africa. Knockdown resistance to pyrethroids and organochlorines in Anopheles gambiae sensu lato (s.l.) is commonly caused by mutations in the gene encoding a voltage-
Externí odkaz:
https://doaj.org/article/38c1075708be481e9f9c83d0238495ec