Zobrazeno 1 - 10
of 3 217
pro vyhledávání: '"Lamellipodium"'
Publikováno v:
eLife, Vol 11 (2022)
For a group of cells to migrate together, each cell must couple the polarity of its migratory machinery with that of the other cells in the cohort. Although collective cell migrations are common in animal development, little is known about how protru
Externí odkaz:
https://doaj.org/article/e8c2d0b3b90c4a129a30d5270aece902
Autor:
Danielle Holz, Aaron R Hall, Eiji Usukura, Sawako Yamashiro, Naoki Watanabe, Dimitrios Vavylonis
Publikováno v:
eLife, Vol 11 (2022)
Single molecule imaging has shown that part of actin disassembles within a few seconds after incorporation into the dendritic filament network in lamellipodia, suggestive of frequent destabilization near barbed ends. To investigate the mechanisms beh
Externí odkaz:
https://doaj.org/article/397cfdc269fd4c0bbf1204a074af4e28
Leading edge maintenance in migrating cells is an emergent property of branched actin network growth
Autor:
Rikki M Garner, Julie A Theriot
Publikováno v:
eLife, Vol 11 (2022)
Animal cell migration is predominantly driven by the coordinated, yet stochastic, polymerization of thousands of nanometer-scale actin filaments across micron-scale cell leading edges. It remains unclear how such inherently noisy processes generate r
Externí odkaz:
https://doaj.org/article/cea7a9cf5b834395bd4e4e9f5cbecea6
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
Cytoskeleton is responsible for fundamental cellular processes and functions. The filamentous actin (F-actin) is a key constituent of the cytoskeleton system which is intrinsically viscoelastic and greatly determines the mechanical properties of cell
Externí odkaz:
https://doaj.org/article/376168cccd01429ba250388c20b0f8e2
Autor:
Vanessa Dimchev, Ines Lahmann, Stefan A. Koestler, Frieda Kage, Georgi Dimchev, Anika Steffen, Theresia E. B. Stradal, Franz Vauti, Hans-Henning Arnold, Klemens Rottner
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The Arp2/3 complex generates branched actin filament networks operating in cell edge protrusion and vesicle trafficking. Here we employ a conditional knockout mouse model permitting tissue- or cell-type specific deletion of the murine Actr3 gene (enc
Externí odkaz:
https://doaj.org/article/b1ab541f9e434beda1080ac675b68dfc
Publikováno v:
The Journal of Cell Biology, 1999 Sep 01. 146(5), 1087-1095.
Externí odkaz:
https://www.jstor.org/stable/1619384
Akademický článek
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Autor:
Aaron R. Hall, Danielle Holz, Sawako Yamashiro, Dimitrios Vavylonis, Naoki Watanabe, Eiji Usukura
Publikováno v:
eLife. 11
Single molecule imaging has shown that part of actin disassembles within a few seconds after incorporation into the dendritic filament network in lamellipodia, suggestive of frequent destabilization near barbed ends. To investigate the mechanisms beh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac907be18dd66adfd1ddd99fb07016b
http://hdl.handle.net/2433/276854
http://hdl.handle.net/2433/276854
Autor:
Sarah Gandarillas, Valérie Choesmel-Cadamuro, Nathalie Van Acker, Camille Franchet, Y Barreira, Christele Segura, Loïc Van Den Berghe, Carine Froment, Klaus M. Hahn, Jiaying Liu, Odile Burlet-Schiltz, Andrei V. Karginov, Xiaobo Wang, Georges Czaplicki, Karine Belguise, Florence Dalenc, Lucie Chadelle
Publikováno v:
Cancer Lett
The cytoskeleton and cell-matrix adhesions constitute a dynamic network that controls cellular behavior during development and cancer. The Focal Adhesion Kinase (FAK) is a central actor of these cell dynamics, promoting cell-matrix adhesion turnover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5c878cf45ba5f3d54a1536a6aecd4d
https://doi.org/10.1016/j.canlet.2021.11.026
https://doi.org/10.1016/j.canlet.2021.11.026
Autor:
Lei-Miao Yin, Michael Schnoor
Publikováno v:
Trends in Cell Biology. 32:94-97
Membrane-cytoskeleton interactions (MCIs) are mediated by actin-binding proteins (ABPs). Ezrin is a crucial ABP that links membranes to actin filaments during lamellipodia formation, cell polarization, and migration. We discuss the concept of MCI and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84eb3ba4993ee5b040d82f33d03758d8
https://doi.org/10.1016/j.tcb.2021.09.005
https://doi.org/10.1016/j.tcb.2021.09.005