Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter Homologue.

Autor: Arkhipova V; University Medical Center Groningen, Department of Radiology, Medical Imaging Center, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.; Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands., Fu H; Department of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands., Hoorens MWH; University Medical Center Groningen, Department of Radiology, Medical Imaging Center, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.; Stratingh Institute for Chemistry, Faculty of Science and Engineering, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands., Trinco G; Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands., Lameijer LN; University Medical Center Groningen, Department of Radiology, Medical Imaging Center, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.; Stratingh Institute for Chemistry, Faculty of Science and Engineering, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands., Marin E; Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.; Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia., Feringa BL; Stratingh Institute for Chemistry, Faculty of Science and Engineering, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands., Poelarends GJ; Department of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands., Szymanski W; University Medical Center Groningen, Department of Radiology, Medical Imaging Center, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.; Stratingh Institute for Chemistry, Faculty of Science and Engineering, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands., Slotboom DJ; Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands., Guskov A; Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.; Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2021 Jan 27; Vol. 143 (3), pp. 1513-1520. Date of Electronic Publication: 2021 Jan 15.

Red-light-sensitive BODIPY photoprotecting groups for amines and their biological application in controlling heart rhythm.

Autor: Sitkowska K; Centre for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands. b.l.feringa@rug.nl and University of Warsaw, Faculty of Chemistry, Pasteura 1, 02-093 Warsaw, Poland., Hoes MF; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Lerch MM; Centre for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands. b.l.feringa@rug.nl., Lameijer LN; Centre for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands. b.l.feringa@rug.nl and Department of Radiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands. w.szymanski@umcg.nl., van der Meer P; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Szymański W; Centre for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands. b.l.feringa@rug.nl and Department of Radiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands. w.szymanski@umcg.nl., Feringa BL; Centre for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands. b.l.feringa@rug.nl.

Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 May 21; Vol. 56 (41), pp. 5480-5483.

Photochemical Resolution of a Thermally Inert Cyclometalated Ru(phbpy)(N-N)(Sulfoxide) ⁺ Complex.

Autor: Lameijer LN; Leiden Institute of Chemistry, Leiden University , Einsteinweg 55 , 2333CC Leiden , The Netherlands., van de Griend C; Leiden Institute of Chemistry, Leiden University , Einsteinweg 55 , 2333CC Leiden , The Netherlands., Hopkins SL; Leiden Institute of Chemistry, Leiden University , Einsteinweg 55 , 2333CC Leiden , The Netherlands., Volbeda AG; Leiden Institute of Chemistry, Leiden University , Einsteinweg 55 , 2333CC Leiden , The Netherlands., Askes SHC; Leiden Institute of Chemistry, Leiden University , Einsteinweg 55 , 2333CC Leiden , The Netherlands., Siegler MA; Small molecule X-ray facility, Department of Chemistry , John Hopkins University , Baltimore , Maryland 21218 , United States., Bonnet S; Leiden Institute of Chemistry, Leiden University , Einsteinweg 55 , 2333CC Leiden , The Netherlands.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2019 Jan 09; Vol. 141 (1), pp. 352-362. Date of Electronic Publication: 2018 Dec 26.

Effects of the Bidentate Ligand on the Photophysical Properties, Cellular Uptake, and (Photo)cytotoxicity of Glycoconjugates Based on the [Ru(tpy)(NN)(L)] ²⁺ Scaffold.

Autor: Lameijer LN; Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA, Leiden, The Netherlands., Brevé TG; Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA, Leiden, The Netherlands., van Rixel VHS; Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA, Leiden, The Netherlands., Askes SHC; Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA, Leiden, The Netherlands., Siegler MA; Departement of Chemistry, Johns Hopkins University, Baltimore, Maryland, 21218, USA., Bonnet S; Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA, Leiden, The Netherlands.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2018 Feb 21; Vol. 24 (11), pp. 2709-2717. Date of Electronic Publication: 2018 Jan 30.

d- Versus l-Glucose Conjugation: Mitochondrial Targeting of a Light-Activated Dual-Mode-of-Action Ruthenium-Based Anticancer Prodrug.

Autor: Lameijer LN; Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA, Leiden, The Netherlands., Hopkins SL; Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA, Leiden, The Netherlands., Brevé TG; Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA, Leiden, The Netherlands., Askes SH; Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA, Leiden, The Netherlands., Bonnet S; Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA, Leiden, The Netherlands.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2016 Dec 19; Vol. 22 (51), pp. 18484-18491. Date of Electronic Publication: 2016 Nov 09.