Oncogenic role of PMEPA1 and its association with immune exhaustion and TGF-β activation in HCC

Autor: Piqué-Gili, Marta, Andreu-Oller, Carmen, Mesropian, Agavni, Esteban-Fabró, Roger, Bárcena-Varela, Marina, Ruiz de Galarreta, Marina, Montironi, Carla, Martinez-Quetglas, Iris, Cappuyns, Sarah, Peix, Judit, Keraite, Ieva, Gris-Oliver, Albert, Fernández-Martínez, Elisa, Mauro, Ezequiel, Torres-Martin, Miguel, Abril-Fornaguera, Jordi, Lindblad, Katherine E., Lambrechts, Diether, Dekervel, Jeroen, Thung, Swan N., Sia, Daniela, Lujambio, Amaia, Pinyol, Roser, Llovet, Josep M.

Publikováno v: In JHEP Reports November 2024 6(11)

Single-cell Atlas of Penile Cancer Reveals TP53 Mutations as a Driver of an Aggressive Phenotype, Irrespective of Human Papillomavirus Status, and Provides Clues for Treatment Personalization

Autor: Elst, Laura, Philips, Gino, Vandermaesen, Kaat, Bassez, Ayse, Lodi, Francesca, Vreeburg, Manon T.A., Brouwer, Oscar R., Schepers, Rogier, Van Brussel, Thomas, Mohanty, Sambit K., Parwani, Anil V., Spans, Lien, Vanden Bempt, Isabelle, Jacomen, Gerd, Baldewijns, Marcella, Lambrechts, Diether, Albersen, Maarten

Publikováno v: In European Urology August 2024 86(2):114-127

Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions

Autor: Dareng, Eileen O., Coetzee, Simon G., Tyrer, Jonathan P., Peng, Pei-Chen, Rosenow, Will, Chen, Stephanie, Davis, Brian D., Dezem, Felipe Segato, Seo, Ji-Heui, Nameki, Robbin, Reyes, Alberto L., Aben, Katja K.H., Anton-Culver, Hoda, Antonenkova, Natalia N., Aravantinos, Gerasimos, Bandera, Elisa V., Beane Freeman, Laura E., Beckmann, Matthias W., Beeghly-Fadiel, Alicia, Benitez, Javier, Bernardini, Marcus Q., Bjorge, Line, Black, Amanda, Bogdanova, Natalia V., Bolton, Kelly L., Brenton, James D., Budzilowska, Agnieszka, Butzow, Ralf, Cai, Hui, Campbell, Ian, Cannioto, Rikki, Chang-Claude, Jenny, Chanock, Stephen J., Chen, Kexin, Chenevix-Trench, Georgia, Chiew, Yoke-Eng, Cook, Linda S., DeFazio, Anna, Dennis, Joe, Doherty, Jennifer A., Dörk, Thilo, du Bois, Andreas, Dürst, Matthias, Eccles, Diana M., Ene, Gabrielle, Fasching, Peter A., Flanagan, James M., Fortner, Renée T., Fostira, Florentia, Gentry-Maharaj, Aleksandra, Giles, Graham G., Goodman, Marc T., Gronwald, Jacek, Haiman, Christopher A., Håkansson, Niclas, Heitz, Florian, Hildebrandt, Michelle A.T., Høgdall, Estrid, Høgdall, Claus K., Huang, Ruea-Yea, Jensen, Allan, Jones, Michael E., Kang, Daehee, Karlan, Beth Y., Karnezis, Anthony N., Kelemen, Linda E., Kennedy, Catherine J., Khusnutdinova, Elza K., Kiemeney, Lambertus A., Kjaer, Susanne K., Kupryjanczyk, Jolanta, Labrie, Marilyne, Lambrechts, Diether, Larson, Melissa C., Le, Nhu D., Lester, Jenny, Li, Lian, Lubiński, Jan, Lush, Michael, Marks, Jeffrey R., Matsuo, Keitaro, May, Taymaa, McLaughlin, John R., McNeish, Iain A., Menon, Usha, Missmer, Stacey, Modugno, Francesmary, Moffitt, Melissa, Monteiro, Alvaro N., Moysich, Kirsten B., Narod, Steven A., Nguyen-Dumont, Tu, Odunsi, Kunle, Olsson, Håkan, Onland-Moret, N. Charlotte, Park, Sue K., Pejovic, Tanja, Permuth, Jennifer B., Piskorz, Anna, Prokofyeva, Darya, Riggan, Marjorie J., Risch, Harvey A., Rodríguez-Antona, Cristina, Rossing, Mary Anne, Sandler, Dale P., Setiawan, V. Wendy, Shan, Kang, Song, Honglin, Southey, Melissa C., Steed, Helen, Sutphen, Rebecca, Swerdlow, Anthony J., Teo, Soo Hwang, Terry, Kathryn L., Thompson, Pamela J., Vestrheim Thomsen, Liv Cecilie, Titus, Linda, Trabert, Britton, Travis, Ruth, Tworoger, Shelley S., Valen, Ellen, Van Nieuwenhuysen, Els, Edwards, Digna Velez, Vierkant, Robert A., Webb, Penelope M., Weinberg, Clarice R., Weise, Rayna Matsuno, Wentzensen, Nicolas, White, Emily, Winham, Stacey J., Wolk, Alicja, Woo, Yin-Ling, Wu, Anna H., Yan, Li, Yannoukakos, Drakoulis, Zeinomar, Nur, Zheng, Wei, Ziogas, Argyrios, Berchuck, Andrew, Goode, Ellen L., Huntsman, David G., Pearce, Celeste L., Ramus, Susan J., Sellers, Thomas A., Freedman, Matthew L., Lawrenson, Kate, Schildkraut, Joellen M., Hazelett, Dennis, Plummer, Jasmine T., Kar, Siddhartha, Jones, Michelle R., Pharoah, Paul D.P., Gayther, Simon A.

Publikováno v: In The American Journal of Human Genetics 6 June 2024 111(6):1061-1083

Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer

Autor: Di Modugno, Francesca, Di Carlo, Anna, Spada, Sheila, Palermo, Belinda, D'Ambrosio, Lorenzo, D'Andrea, Daniel, Morello, Gaia, Belmonte, Beatrice, Sperduti, Isabella, Balzano, Vittoria, Gallo, Enzo, Melchionna, Roberta, Panetta, Mariangela, Campo, Giulia, De Nicola, Francesca, Goeman, Frauke, Antoniani, Barbara, Carpano, Silvia, Frigè, Gianmaria, Warren, Sarah, Gallina, Filippo, Lambrechts, Diether, Xiong, Jieyi, Vincent, Benjamin G., Wheeler, Nathan, Bortone, Dante S., Cappuzzo, Federico, Facciolo, Francesco, Tripodo, Claudio, Visca, Paolo, Nisticò, Paola

Publikováno v: In eBioMedicine March 2024 101

A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma

Autor: Pozniak, Joanna, Pedri, Dennis, Landeloos, Ewout, Van Herck, Yannick, Antoranz, Asier, Vanwynsberghe, Lukas, Nowosad, Ada, Roda, Niccolò, Makhzami, Samira, Bervoets, Greet, Maciel, Lucas Ferreira, Pulido-Vicuña, Carlos Ariel, Pollaris, Lotte, Seurinck, Ruth, Zhao, Fang, Flem-Karlsen, Karine, Damsky, William, Chen, Limin, Karagianni, Despoina, Cinque, Sonia, Kint, Sam, Vandereyken, Katy, Rombaut, Benjamin, Voet, Thierry, Vernaillen, Frank, Annaert, Wim, Lambrechts, Diether, Boecxstaens, Veerle, Saeys, Yvan, van den Oord, Joost, Bosisio, Francesca, Karras, Panagiotis, Shain, A. Hunter, Bosenberg, Marcus, Leucci, Eleonora, Paschen, Annette, Rambow, Florian, Bechter, Oliver, Marine, Jean-Christophe

Publikováno v: In Cell 4 January 2024 187(1):166-183