Levamisole Modulation of Podocytes’ Actin Cytoskeleton in Nephrotic Syndrome

Autor: Susan T. Veissi, Tijmen van den Berge, Joanna A. E. van Wijk, Thea van der Velden, René Classens, Lynn Lunsonga, Rick Brockotter, Charlotte Kaffa, Sander Bervoets, Bart Smeets, Lambertus P. W. J. van den Heuvel, Michiel F. Schreuder

Publikováno v: Biomedicines, Vol 11, Iss 11, p 3039 (2023)

Podocytes play a central role in glomerular diseases such as (idiopathic) nephrotic syndrome (iNS). Glucocorticoids are the gold standard therapy for iNS. Nevertheless, frequent relapses are common. In children with iNS, steroid-sparing agents are us

Externí odkaz: https://doaj.org/article/53fbe27fff824e44b1ba5bf494b676ef

Case Report: Variable Pharmacokinetic Profile of Eculizumab in an aHUS Patient

Autor: Romy N. Bouwmeester, Mendy Ter Avest, Kioa L. Wijnsma, Caroline Duineveld, Rob ter Heine, Elena B. Volokhina, Lambertus P. W. J. Van Den Heuvel, Jack F. M. Wetzels, Nicole C. A. J. van de Kar

Publikováno v: Frontiers in Immunology, Vol 11 (2021)

BackgroundWith the introduction of eculizumab, a C5-inhibitor, morbidity and mortality improved significantly for patients with atypical hemolytic uremic syndrome (aHUS). In view of the high costs, actual needs of the drug, and increasing evidence in

Externí odkaz: https://doaj.org/article/23408f3b87bb415c8e88c8a8caae52f7

Shiga Toxin Selectively Upregulates Expression of Syndecan-4 and Adhesion Molecule ICAM-1 in Human Glomerular Microvascular Endothelium

Autor: Elena B. Volokhina, Wouter J. C. Feitz, Lonneke M. Elders, Thea J. A. M. van der Velden, Nicole C. A. J. van de Kar, Lambertus P. W. J. van den Heuvel

Publikováno v: Toxins, Vol 12, Iss 7, p 435 (2020)

Hemolytic uremic syndrome (HUS) is a severe renal disease that is often preceded by infection with Shiga toxin (Stx)-producing Escherichia coli (STEC). The exact mechanism of Stx-mediated inflammation on human glomerular microvascular endothelial cel

Externí odkaz: https://doaj.org/article/0426338df34e4197bdda8c3d329f49cb

Plasma exchange or immunoadsorption for recurrent focal segmental glomerulosclerosis:clear differences in vitro

Autor: Susan T Veissi, Bart Smeets, Joanna A E van Wijk, Thea van der Velden, Lambertus P W J van den Heuvel, Michiel F Schreuder

Publikováno v: Veissi, S T, Smeets, B, van Wijk, J A E, van der Velden, T, van den Heuvel, L P W J & Schreuder, M F 2022, ' Plasma exchange or immunoadsorption for recurrent focal segmental glomerulosclerosis : clear differences in vitro ', Nephrology Dialysis Transplantation, vol. 37, no. 11, pp. 2293-2294 . https://doi.org/10.1093/ndt/gfac255
Nephrology, Dialysis, Transplantation, 37, 2293-2294
Nephrology, Dialysis, Transplantation, 37, 11, pp. 2293-2294

Contains fulltext : 287636.pdf (Publisher’s version ) (Open Access)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b6489c5cee4de4fe768fedb8399e2d
https://research.vumc.nl/en/publications/411a36c1-11bb-4c94-a9f3-ea5d2a970947

Mutations in the chloride channel gene CLCNKB as a cause of classic Bartter syndrome

Autor: Nikola Jeck, Alicia Lakings, Delphine Feldmann, Friedhelm Hildebrandt, Nine V A M Knoers, Lisa M. Guay-Woodford, Henny H. Lemmink, Georges Deschênes, Rainer G. Ruf, Hannsjörg W. Seyberth, Martin Konrad, Lambertus P. W. J. Van Den Heuvel, Rosa Vargas-Poussou, Corinne Antignac, Martin Vollmer

Publikováno v: Journal of the American Society of Nephrology, 11, 8, pp. 1449-1459
CIÊNCIAVITAE
Journal of the American Society of Nephrology, 11, 1449-1459
Europe PubMed Central

Inherited hypokalemic renal tubulopathies are differentiated into at least three clinical subtypes: (1) the Gitelman variant of Bartter syndrome (GS); (2) hyperprostaglandin E syndrome, the antenatal variant of Bartter syndrome (HPS/aBS); and (3) the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb61cc371884ce98cd7bf40068d11e37
https://hdl.handle.net/2066/184566