Identification and Characterization of an Activating TrkA Deletion Mutation in Acute Myeloid Leukemia

Autor: Caligiuri, M. A., Lambert, Q. T., Der, C. J., Reuther, G. W.

In this study, we utilized retroviral transfer of cDNA libraries in order to identify oncogenes that are expressed in acute myeloid leukemia (AML). From screens using two different cell types as targets for cellular transformation, a single cDNA enco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c4745b32824f1f67d5c424eec7eee9b

Heteroduplex formation: a potential source of genotyping error from PCR products.

Autor: Hatcher, Sandra L. S., Lambert, Que Trang, Teplitz, Raymond L., Carlson, James R., Hatcher, S L, Lambert, Q T, Teplitz, R L, Carlson, J R

Publikováno v: Prenatal Diagnosis; Mar1993, Vol. 13 Issue 3, p171-177, 7p

The src homology 2 and phosphotyrosine binding domains of the ShcC adaptor protein function as inhibitors of mitogenic signaling by the epidermal growth factor receptor.

Autor: O'Bryan, J P, Lambert, Q T, Der, C J

Publikováno v: Journal of Biological Chemistry; August 1998, Vol. 273 Issue: 32 p20431-7, 7p

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

Autor: Westwick, J K, Lambert, Q T, Clark, G J, Symons, M, Van Aelst, L, Pestell, R G, Der, C J

Publikováno v: Molecular and Cellular Biology; March 1997, Vol. 17 Issue: 3 p1324-1335, 12p

Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA.

Autor: Reuther GW; Department of Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295, USA. greuther@med.unc.edu, Lambert QT, Booden MA, Wennerberg K, Becknell B, Marcucci G, Sondek J, Caligiuri MA, Der CJ

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2001 Jul 20; Vol. 276 (29), pp. 27145-51. Date of Electronic Publication: 2001 May 23.