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Akademický článek

Recognition of the HLA Class II-Peptide Complex by T-Cell Receptor: Reversal of Major Histocompatibility Complex Restriction of a T-Cell Clone by a Point Mutation in the Peptide Determinant [and Discussion]

Autor: Rothbard, J. B., Busch, R., Lechler, R., Trowsdale, J., Lamb, J. R., Nicholson, B. H.

Publikováno v: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 1989 Jun 01. 323(1217), 553-564.

Externí odkaz: https://www.jstor.org/stable/2396881

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Influence of antigen structure on the activation and induction of unresponsiveness in cloned human T lymphocytes

Autor: Lamb, J R, Feldmann, M, Green, N, Lerner, R A

Using cloned human helper T lymphocytes reactive with a 24 amino acid peptide (p20) of the carboxyl terminal of the HA-1 molecule of influenza haemagglutinin we have investigated the influence of antigen structure on the activation and in the inducti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b368fb64ad74c5d206ce52a0fb0dd02b
https://ora.ox.ac.uk/objects/uuid:58c836c0-4f14-4f69-b1ef-5aa46e6a56c0

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Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes

Autor: Essery, G, Feldmann, M, Lamb, J R

The exposure of human T-cell clones to supra-immunogenic concentrations of peptide antigen in the absence of accessory cells induces antigen-specific unresponsiveness. Using this model we have investigated the ability of cytokines to modulate the ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fd6db3a152d01905312311042202c61a
https://ora.ox.ac.uk/objects/uuid:d463e45d-10b4-4a10-b947-cc4e6493f60a

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