Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lamara D. Shrode"'
Autor:
E. Krump, Lamara D. Shrode, C M Howard, Sergio Grinstein, Elizabeth A. Rubie, D Gillis, James R. Woodgett, L. A. Tibbles
Publikováno v:
The Journal of Membrane Biology. 181:205-214
The Na+/H+ exchanger (NHE) becomes activated by hyperosmolar stress, thereby contributing to cell volume regulation. The signaling pathway(s) responsible for the shrinkage-induced activation of NHE, however, remain unknown. A family of mitogen-activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ae4d28428208611300345d5b5ec1f5
https://doi.org/10.1007/s00232-001-0023-3
https://doi.org/10.1007/s00232-001-0023-3
Publikováno v:
American Journal of Physiology-Cell Physiology. 272:C1968-C1979
Previously, we suggested that myosin light chain kinase (MLCK) is involved in shrinkage-induced activation of the Na+/H+ exchanger in rat astrocytes. Here we have studied the effects of hyperosmotic exposure in C6 glioma cells, a common model for ast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d8077c3dc87ddcabc337c91050d555
https://doi.org/10.1152/ajpcell.1997.272.6.c1968
https://doi.org/10.1152/ajpcell.1997.272.6.c1968
Publikováno v:
Journal of Bioenergetics and Biomembranes. 29:393-399
Both cellular proliferation and apoptosis (programmed cell death) have been claimed to be modulated, perhaps even triggered by, changes in intracellular pH. In this review, we summarize the evidence that gave rise to these hypotheses. To facilitate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::215e3ad9bba8f9ee40bd01456b7a84a6
https://doi.org/10.1023/a:1022407116339
https://doi.org/10.1023/a:1022407116339
Autor:
Lamara D. Shrode, Robert W. Putnam
Publikováno v:
Glia. 12:196-210
We used the pH-sensitive fluorescent dye BCECF to study intracellular pH (pHi) regulation in primary cultures of rat astrocytes and C6 glioma cells. Both cell types contain three pH-regulating transporters: 1) alkalinizing Na+/H+ exchange; 2) alkalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbae1215a6400e8d0486bdf0725c47e1
https://doi.org/10.1002/glia.440120305
https://doi.org/10.1002/glia.440120305
Autor:
Michael F. Romero, Christopher M. Sciortino, Bonnie R. Fletcher, Peter J. Harte, Lamara D. Shrode
Publikováno v:
American journal of physiology. Cell physiology. 281(2)
Na+-dependent Cl−/HCO[Formula: see text]exchange activity helps maintain intracellular pH (pHi) homeostasis in many invertebrate and vertebrate cell types. Our laboratory cloned and characterized a Na+-dependent Cl−/HCO[Formula: see text] exchang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0abff955a80ec9169748f8c6d9cd27
https://pubmed.ncbi.nlm.nih.gov/11443044
https://pubmed.ncbi.nlm.nih.gov/11443044
Publikováno v:
The American journal of physiology. 275(4)
Although used extensively for the measurement of intracellular pH, derivatives of fluorescein such as 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein (BCECF) have suboptimal sensitivity and can generate toxic photoproducts. These limitations ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c474e5f374a6a312cd4cc2ce5f117bb8
https://pubmed.ncbi.nlm.nih.gov/9755070
https://pubmed.ncbi.nlm.nih.gov/9755070
Publikováno v:
The American journal of physiology. 275(2)
Proteases, glycosidases, and impermeant biotin derivatives were used in combination with antibodies to analyze the subcellular distribution and transmembrane disposition of the Na+/H+exchanger NHE1. Both native human NHE1 in platelets and epitope-tag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda4160674b3e6af82e44675f68d9479
https://pubmed.ncbi.nlm.nih.gov/9688597
https://pubmed.ncbi.nlm.nih.gov/9688597
Publikováno v:
The Journal of biological chemistry. 272(21)
Stress-activated protein kinases (SAPK) are stimulated by a variety of agents and conditions that also activate the Na+/H+ exchanger (NHE). Activation of the exchanger results in a rapid increase in intracellular pH (pHi), raising the possibility tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7cc9da5e3237b5d92ad6106cab46cf2
https://pubmed.ncbi.nlm.nih.gov/9153215
https://pubmed.ncbi.nlm.nih.gov/9153215
Autor:
Ori D. Rotstein, Morris F. Manolson, Tommy Nordström, Robert Romanek, Lamara D. Shrode, Sergio Grinstein, Guy F. Brisseau, J. N. M. Heersche, Tetsuya Goto
Publikováno v:
ResearcherID
Proton extrusion into an extracellular resorption compartment is an essential component of bone degradation by osteoclasts. Chronic metabolic acidosis is known to induce negative calcium balance and bone loss by stimulating osteoclastic bone resorpti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd6cd6bf278f6f6dfa76a9fb93a19e1
https://pubmed.ncbi.nlm.nih.gov/9045656
https://pubmed.ncbi.nlm.nih.gov/9045656