Výsledky vyhledávání - "Lama ElZohary"

Akademický článek

Placental co-transcriptional activator Vestigial-like 1 (VGLL1) drives tumorigenesis via increasing transcription of proliferation and invasion genes

Autor: Heather M. Sonnemann, Barbara Pazdrak, Barbara Nassif, Yimo Sun, Lama Elzohary, Amjad H. Talukder, Arjun S. Katailiha, Krishna Bhat, Gregory Lizée

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

IntroductionVestigial-like 1 (VGLL1) is a co-transcriptional activator that binds to TEA domain-containing transcription factors (TEADs). Its expression is upregulated in a variety of aggressive cancer types, including pancreatic and basal-like breas

Externí odkaz: https://doaj.org/article/d25bbf27559a40dbbe381989efdb6b3e

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Akademický článek

Epidermal Growth Factor Receptor-Targeted Neoantigen Peptide Vaccination for the Treatment of Non-Small Cell Lung Cancer and Glioblastoma

Autor: Fenge Li, Huancheng Wu, Xueming Du, Yimo Sun, Barbara Nassif Rausseo, Amjad Talukder, Arjun Katailiha, Lama Elzohary, Yupeng Wang, Zhiyu Wang, Gregory Lizée

Publikováno v: Vaccines, Vol 11, Iss 9, p 1460 (2023)

The epidermal growth factor receptor (EGFR) plays crucial roles in several important biological functions such as embryogenesis, epithelial tissue development, and cellular regeneration. However, in multiple solid tumor types overexpression and/or ac

Externí odkaz: https://doaj.org/article/0029dc69d08349b1b2780250d5f25b04

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Akademický článek

Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats.

Autor: Lama ElZohary, William B Weglicki, Joanna J Chmielinska, Jay H Kramer, I Tong Mak

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0210107 (2019)

We determined if HIV-1 expression in transgenic (HIV-1-Tg) rats enhanced hepatic genomic changes related to oxidative/nitrosative stress and lipogenesis during cART-treatment, and assessed effects of Mg-supplementation. A clinically used cART (atazan

Externí odkaz: https://doaj.org/article/d4892e25a4ee46c5a3e056cc11b787f5

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Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats

Autor: Jay H. Kramer, William B. Weglicki, I. Tong Mak, Lama Elzohary, Joanna J. Chmielinska

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0210107 (2019)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db49dd6ba2d96f56a70851804fac0949
https://doi.org/10.1371/journal.pone.0210107

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Combination Antiretroviral Therapy (cART) Altered Redox/Nitrosative genes, Enhanced Systemic Stress and Cardiac dysfunction in HIV-1 Transgenic (HIV-Tg) Rats: Effects of Magnesium Supplementation (Mg-Supp)

Autor: Chris Spurney, I.T. Mak, Lama Elzohary, William B. Weglicki, Jay H. Kramer, Joanna J. Chmielinska

Publikováno v: Free Radical Biology and Medicine. 112:117

We determined if clinically used cART promoted redox/nitrosative stress and cardiac toxicity in control and HIV-Tg rats and the effects of Mg. Treatment with cART (Truvada+atazanavir/ritonavir) up to 18 weeks, induced significant hypomagnesemia (-25%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8b89424810b92cb95011fd2534f48ff
https://doi.org/10.1016/j.freeradbiomed.2017.10.175

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