Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease.

Autor: Rajani RM; UK Dementia Research Institute at UCL, University College London, London, United Kingdom., Ellingford R; UK Dementia Research Institute at UCL, University College London, London, United Kingdom., Hellmuth M; UK Dementia Research Institute at UCL, University College London, London, United Kingdom., Harris SS; UK Dementia Research Institute at UCL, University College London, London, United Kingdom., Taso OS; UK Dementia Research Institute at UCL, University College London, London, United Kingdom., Graykowski D; UK Dementia Research Institute at UCL, University College London, London, United Kingdom., Lam FKW; UK Dementia Research Institute at UCL, University College London, London, United Kingdom., Arber C; Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, London, United Kingdom., Fertan E; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom.; UK Dementia Research Institute at University of Cambridge, Cambridge, United Kingdom., Danial JSH; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom.; UK Dementia Research Institute at University of Cambridge, Cambridge, United Kingdom.; School of Physics and Astronomy, University of St Andrews, St. Andrews, United Kingdom., Swire M; Wolfson Institute for Biomedical Research, University College London, London, United Kingdom., Lloyd M; Wolfson Institute for Biomedical Research, University College London, London, United Kingdom., Giovannucci TA; Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, London, United Kingdom., Bourdenx M; UK Dementia Research Institute at UCL, University College London, London, United Kingdom., Klenerman D; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom.; UK Dementia Research Institute at University of Cambridge, Cambridge, United Kingdom., Vassar R; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America., Wray S; Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, London, United Kingdom., Sala Frigerio C; UK Dementia Research Institute at UCL, University College London, London, United Kingdom., Busche MA; UK Dementia Research Institute at UCL, University College London, London, United Kingdom.

Publikováno v: PLoS biology [PLoS Biol] 2024 Jul 23; Vol. 22 (7), pp. e3002727. Date of Electronic Publication: 2024 Jul 23 (Print Publication: 2024).