Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lam Bernice M T"'
Autor:
Kevin M. Krause, Bettina Bazzini, J. Kevin Judice, Burton G. Christensen, Michael R. Leadbetter, Dane E. Karr, Sean G. Trapp, Elizabeth Soriano, Jeng-Pyng Shaw, Paul R. Fatheree, Kelly L. Quast, Lam Bernice M T, Martin S. Linsell, Matthew B. Nodwell, Terry X. Wu, John L. Pace, Jenny D. Villena, Stacy M. Adams
Publikováno v:
The Journal of Antibiotics. 57:326-336
Novel derivatives of N-decylaminoethylvancomycin (2), containing appended hydrophilic groups were synthesized and their antibacterial activity and ADME properties were evaluated. The compounds were prepared by reacting amines with the C-terminus (C-)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6222c56379e55f3952bdb5a808e761
https://doi.org/10.7164/antibiotics.57.326
https://doi.org/10.7164/antibiotics.57.326
Hydrophobic vancomycin derivatives with improved ADME properties: discovery of telavancin (TD-6424).
Autor:
Leadbetter MR; Theravance, Inc., 901 Gateway Blvd., South San Francisco, CA 94080, USA. mleadbetter@theravance.com, Adams SM, Bazzini B, Fatheree PR, Karr DE, Krause KM, Lam BM, Linsell MS, Nodwell MB, Pace JL, Quast K, Shaw JP, Soriano E, Trapp SG, Villena JD, Wu TX, Christensen BG, Judice JK
Publikováno v:
The Journal of antibiotics [J Antibiot (Tokyo)] 2004 May; Vol. 57 (5), pp. 326-36.