3D co-culture spheroid drug screening platform for pancreatic cancer invasion

Autor: Lam, Hoyin

Pancreatic ductal adenocarcinoma (PDAC) is the 5th most common cause of death by cancer in the UK, accounting for 5% of all cancer deaths in the UK. Only 8% of the PDAC patients from all stages combined, survives for 5 years or longer. Late stage dia

Externí odkaz: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.745393

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Deciphering the link between PI3K and PAK:An opportunity to target key pathways in pancreatic cancer?

Autor: Thillai, Kiruthikah, Lam, Hoyin, Sarker, Debashis, Wells, Claire M.

Publikováno v: Thillai, K, Lam, H, Sarker, D & Wells, C M 2016, ' Deciphering the link between PI3K and PAK : An opportunity to target key pathways in pancreatic cancer? ', Oncotarget, vol. 8, no. 8, pp. 14173-14191 . https://doi.org/10.18632/oncotarget.13309

The development of personalised therapies has ushered in a new and exciting era of cancer treatment for a variety of solid malignancies. Yet pancreatic ductal adenocarcinoma (PDAC) has failed to benefit from this paradigm shift, remaining notoriously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2761::72c9ccd7c4b76b8a9edb76041006bd6f
https://kclpure.kcl.ac.uk/en/publications/322a7701-85bc-4d1c-b30b-288d06651adf

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In vitro models of drug screening for pancreatic cancer

Autor: Lam, Hoyin, Sarker, Debashis, Wells, Claire

Publikováno v: In Pancreatology June 2016 16(3) Supplement:S8-S8