Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Lam, Brian YH"'
The vagus nerve mediates the physiological but not pharmacological effects of PYY3-36 on food intake
Autor:
Alonso, Aldara Martin, Cork, Simon C., Phuah, Phyllis, Hansen, Benjamin, Norton, Mariana, Cheng, Sijing, Xu, Xiang, Suba, Kinga, Ma, Yue, Dowsett, Georgina KC., Tadross, John A., Lam, Brian YH., Yeo, Giles SH., Herzog, Herbert, Bloom, Stephen R., Arnold, Myrtha, Distaso, Walter, Murphy, Kevin G., Salem, Victoria
Publikováno v:
In Molecular Metabolism March 2024 81
Autor:
Duckett, Katie, Williamson, Alice, Kincaid, John WR, Rainbow, Kara, Corbin, Laura J, Martin, Hilary C, Eberhardt, Ruth Y, Huang, Qin Qin, Hurles, Matthew E, He, Wen, Brauner, Raja, Delaney, Angela, Dunkel, Leo, Grinspon, Romina P, Hall, Janet E, Hirschhorn, Joel N, Howard, Sasha R, Latronico, Ana C, Jorge, Alexander AL, McElreavey, Ken, Mericq, Verónica, Merino, Paulina M, Palmert, Mark R, Plummer, Lacey, Rey, Rodolfo A, Rezende, Raíssa C, Seminara, Stephanie B, Salnikov, Kathryn, Banerjee, Indraneel, Lam, Brian YH, Perry, John RB, Timpson, Nicholas J, Clayton, Peter, Chan, Yee-Ming, Ong, Ken K, O'Rahilly, Stephen
Publikováno v:
Duckett, K, Williamson, A, Kincaid, J W R, Rainbow, K, Corbin, L J, Martin, H C, Eberhardt, R Y, Huang, Q Q, Hurles, M E, He, W, Brauner, R, Delaney, A, Dunkel, L, Grinspon, R P, Hall, J E, Hirschhorn, J N, Howard, S R, Latronico, A C, Jorge, A A L, Mcelreavey, K, Mericq, V, Merino, P M, Palmert, M R, Plummer, L, Rey, R A, Rezende, R C, Seminara, S B, Salnikov, K, Banerjee, I, Lam, B Y H, Perry, J R B, Timpson, N J, Clayton, P, Chan, Y-M, Ong, K K & O’rahilly, S 2023, ' Prevalence of deleterious variants in MC3R in patients with constitutional delay of growth and puberty ', The Journal of Clinical Endocrinology & Metabolism . https://doi.org/10.1210/clinem/dgad373
ContextThe melanocortin 3 receptor (MC3R) has recently emerged as a critical regulator of pubertal timing, linear growth and the acquisition of lean mass in humans and mice. In population-based studies, heterozygous carriers of deleterious variants i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afedd926f408e196784190770ba8b48d
Autor:
Steuernagel, Lukas, Lam, Brian YH, Klemm, Paul, Dowsett, Georgina KC, Bauder, Corinna A, Tadross, John A, Hitschfeld, Tamara Sotelo, Del Rio Martin, Almudena, Chen, Weiyi, De Solis, Alain J, Fenselau, Henning, Davidsen, Peter, Cimino, Irene, Kohnke, Sara N, Rimmington, Debra, Coll, Anthony P, Beyer, Andreas, Yeo, Giles SH, Brüning, Jens C
The hypothalamus plays a key role in coordinating fundamental body functions. Despite recent progress in single-cell technologies, a unified catalogue and molecular characterization of the heterogeneous cell types and, specifically, neuronal subtypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0169b410d5f3fccf9659c789cc68b98
https://www.repository.cam.ac.uk/handle/1810/343489
https://www.repository.cam.ac.uk/handle/1810/343489
Autor:
Wade, Kaitlin H, Lam, Brian YH, Melvin, Audrey, Pan, Warren, Corbin, Laura J, Hughes, David A, Rainbow, Kara, Chen, Jian-Hua, Duckett, Katie, Liu, Xiaoming, Mokrosiński, Jacek, Mörseburg, Alexander, Neaves, Sam, Williamson, Alice, Zhang, Chen, Farooqi, I Sadaf, Yeo, Giles SH, Timpson, Nicholas J, O'Rahilly, Stephen
Mutations in the melanocortin 4 receptor gene (MC4R) are associated with obesity but little is known about the prevalence and impact of such mutations throughout human growth and development. We examined the MC4R coding sequence in 5,724 participants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::8df96f1084f3d520e02e580085cda319
https://www.repository.cam.ac.uk/handle/1810/321319
https://www.repository.cam.ac.uk/handle/1810/321319
Autor:
Yu, Xian, Newland, Stephen A, Zhao, Tian X, Lu, Yuning, Sage, Andrew S, Sun, Yanyi, Sriranjan, Rouchelle S, Ma, Marcella KL, Lam, Brian YH, Nus, Meritxell, Harrison, James E, Bond, Simon J, Cheng, Xiang, Silvestre, Jean-Sébastien, Rudd, James HF, Cheriyan, Joseph, Mallat, Ziad
BACKGROUND: Innate lymphoid cells type 2 (ILC2s) play critical homeostatic functions in peripheral tissues. ILC2s reside in perivascular niches and limit atherosclerosis development. OBJECTIVES: ILC2s also reside in the pericardium but their role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de52f963f37104f81bfb50c6a7589bdf
Autor:
Wray, Jonathan R, Davies, Alison, Sefton, Charlotte, Allen, Tiffany-Jayne, Adamson, Antony, Chapman, Philip, Lam, Brian YH, Yeo, Giles SH, Coll, Anthony P, Harno, Erika, White, Anne
Publikováno v:
Molecular Metabolism
Wray, J, Davies, A, Sefton, C, Allen, T-J, Adamson, A, Chapman, P, Lam, B Y H, Yeo, G S H, Coll, A P, Harno, E & White, A 2019, ' Global Transcriptomic Analysis of the Arcuate Nucleus following Chronic Glucocorticoid Treatment ', Molecular Metabolism, vol. 26, pp. 5-17 . https://doi.org/10.1016/j.molmet.2019.05.008
Molecular Metabolism, Vol 26, Iss, Pp 5-17 (2019)
Wray, J, Davies, A, Sefton, C, Allen, T-J, Adamson, A, Chapman, P, Lam, B Y H, Yeo, G S H, Coll, A P, Harno, E & White, A 2019, ' Global Transcriptomic Analysis of the Arcuate Nucleus following Chronic Glucocorticoid Treatment ', Molecular Metabolism, vol. 26, pp. 5-17 . https://doi.org/10.1016/j.molmet.2019.05.008
Molecular Metabolism, Vol 26, Iss, Pp 5-17 (2019)
Objective Glucocorticoids (GCs) are widely prescribed medications that are well recognized to cause adverse metabolic effects including hyperphagia, obesity, and hyperglycemia. These effects have been recapitulated in a murine model of GC excess, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e90c1e8f10bcf1ef631294304e0bc008
http://europepmc.org/articles/PMC6667392
http://europepmc.org/articles/PMC6667392
Autor:
Klus Petr, Lam Simon, Lyberg Dag, Cheung Ming, Pullan Graham, McFarlane Ian, Yeo Giles SH, Lam Brian YH
Publikováno v:
BMC Research Notes, Vol 5, Iss 1, p 27 (2012)
Abstract Background With the maturation of next-generation DNA sequencing (NGS) technologies, the throughput of DNA sequencing reads has soared to over 600 gigabases from a single instrument run. General purpose computing on graphics processing units
Externí odkaz:
https://doaj.org/article/79f14572a4dd414da659fdfd0dfec733
Autor:
Nus, Meritxell, Sage, Andy P., Lu, Yuning, Masters, Leanne, Lam, Brian Yh, Newland, Stephen, Weller, Sandra, Tsiantoulas, Dimitrios, Raffort, Juliette, Marcus, Damienne, Finigan, Alison, Kitt, Lauren, Figg, Nichola, Schirmbeck, Reinhold, Kneilling, Manfred, Yeo, Giles Sh, Binder, Christoph J., De La Pompa, Jose L., Mallat, Ziad
Publikováno v:
In Atherosclerosis August 2017 263:e12-e13
Autor:
Hameed, Saira, Patterson, Michael, Dhillo, Waljit S, Rahman, Sofia A, Ma, Yue, Holton, Christopher, Gogakos, Apostolos, Yeo, Giles SH, Lam, Brian YH, Polex-Wolf, Joseph, Fenske, Wiebke, Bell, Jimmy, Anastasovska, Jelena, Samarut, Jacques, Bloom, Stephen R, Bassett, JH Duncan, Williams, Graham R, Gardiner, James V
The obesity epidemic is a significant global health issue. Improved understanding of the mechanisms that regulate appetite and body weight will provide the rationale for the design of anti-obesity therapies. Thyroid hormones play a key role in metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b037e66d45f683aad752b70f09aaf29
Autor:
Adriaenssens, Alice E, Svendsen, Berit, Lam, Brian YH, Yeo, Giles SH, Holst, Jens J, Reimann, Frank, Gribble, Fiona M
AIMS/HYPOTHESIS: Intra-islet and gut-islet crosstalk are critical in orchestrating basal and postprandial metabolism. The aim of this study was to identify regulatory proteins and receptors underlying somatostatin secretion though the use of transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36e7b56bd389e0a75df1455461586975