Respiratory tract Moraxella catarrhalis and Klebsiella pneumoniae can promote pathogenicity of myelin-reactive Th17 cells.

Autor: Mannion JM; Host-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Segal BM; Department of Neurology and the Neuroscience Research Institute, The Ohio State University Wexner Medical Center, Columbus, USA; Department of Neurology, University of Michigan, Ann Arbor, USA., McLoughlin RM; Host-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Lalor SJ; University College Dublin School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland. Electronic address: stephen.lalor@ucd.ie.

Publikováno v: Mucosal immunology [Mucosal Immunol] 2023 Aug; Vol. 16 (4), pp. 399-407. Date of Electronic Publication: 2023 Apr 23.

The Airway Microbiome-IL-17 Axis: a Critical Regulator of Chronic Inflammatory Disease.

Autor: Mannion JM; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., McLoughlin RM; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Lalor SJ; UCD School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland. stephen.lalor@ucd.ie.

Publikováno v: Clinical reviews in allergy & immunology [Clin Rev Allergy Immunol] 2023 Apr; Vol. 64 (2), pp. 161-178. Date of Electronic Publication: 2022 Mar 11.

A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans.

Autor: Edwards SC; Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Sutton CE; Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Ladell K; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Grant EJ; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK.; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., McLaren JE; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Roche F; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Dash P; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN., Apiwattanakul N; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN.; Division of Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand., Awad W; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN., Miners KL; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Lalor SJ; Host Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Ribot JC; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., Baik S; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, Medical School, University of Birmingham, Edgbaston, Birmingham, UK., Moran B; Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., McGinley A; Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Pivorunas V; AbbVie Bioresearch Center, Inc., Worcester, MA., Dowding L; AbbVie Bioresearch Center, Inc., Worcester, MA., Macoritto M; AbbVie Bioresearch Center, Inc., Worcester, MA., Paez-Cortez J; AbbVie Bioresearch Center, Inc., Worcester, MA., Slavin A; AbbVie Bioresearch Center, Inc., Worcester, MA., Anderson G; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, Medical School, University of Birmingham, Edgbaston, Birmingham, UK., Silva-Santos B; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., Hokamp K; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Price DA; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK., Thomas PG; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN., McLoughlin RM; Host Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Mills KHG; Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

Publikováno v: The Journal of experimental medicine [J Exp Med] 2020 May 04; Vol. 217 (5).

The circadian protein BMAL1 in myeloid cells is a negative regulator of allergic asthma.

Autor: Zasłona Z; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; and., Case S; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; and., Early JO; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; and., Lalor SJ; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; and., McLoughlin RM; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; and., Curtis AM; Molecular and Cellular Therapeutics Department, Royal College of Surgeons in Ireland, Dublin, Ireland., O'Neill LAJ; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; and laoneill@tcd.ie.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2017 Jun 01; Vol. 312 (6), pp. L855-L860. Date of Electronic Publication: 2017 Mar 23.

Antibodies to the RNA-binding protein hnRNP A1 contribute to neurodegeneration in a model of central nervous system autoimmune inflammatory disease.

Autor: Douglas JN; Department of Neurology, University of Tennessee Health Science Center, 855 Monroe Avenue, Room 415, Memphis, TN, 38163, USA.; The Neuroscience Institute, University of Tennessee Health Science Center, Memphis, TN, USA., Gardner LA; Research Service, VA Medical Center, Memphis, TN, USA.; Department of Neurology, University of Tennessee Health Science Center, 855 Monroe Avenue, Room 415, Memphis, TN, 38163, USA.; The Neuroscience Institute, University of Tennessee Health Science Center, Memphis, TN, USA., Salapa HE; Department of Neurology, University of Tennessee Health Science Center, 855 Monroe Avenue, Room 415, Memphis, TN, 38163, USA.; The Neuroscience Institute, University of Tennessee Health Science Center, Memphis, TN, USA., Lalor SJ; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA., Lee S; Research Service, VA Medical Center, Memphis, TN, USA.; Department of Neurology, University of Tennessee Health Science Center, 855 Monroe Avenue, Room 415, Memphis, TN, 38163, USA.; The Neuroscience Institute, University of Tennessee Health Science Center, Memphis, TN, USA., Segal BM; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA.; Neurology Service, VA Ann Arbor Health Care System, Ann Arbor, MI, USA., Sawchenko PE; Laboratory of Neuronal Structure & Function, The Salk Institute, La Jolla, CA, USA., Levin MC; Research Service, VA Medical Center, Memphis, TN, USA. mlevin@uthsc.edu.; Department of Neurology, University of Tennessee Health Science Center, 855 Monroe Avenue, Room 415, Memphis, TN, 38163, USA. mlevin@uthsc.edu.; The Neuroscience Institute, University of Tennessee Health Science Center, Memphis, TN, USA. mlevin@uthsc.edu.

Publikováno v: Journal of neuroinflammation [J Neuroinflammation] 2016 Jul 08; Vol. 13 (1), pp. 178. Date of Electronic Publication: 2016 Jul 08.