Machine Learning of Bone Marrow Histopathology Identifies Genetic and Clinical Determinants in Patients with MDS.

Autor: Brück OE; Hematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland.; Helsinki University Hospital Comprehensive Cancer Center, Department of Hematology, Helsinki, Finland., Lallukka-Brück SE; Hematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland., Hohtari HR; Hematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland., Ianevski A; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland., Ebeling FT; Helsinki University Hospital Comprehensive Cancer Center, Department of Hematology, Helsinki, Finland., Kovanen PE; Department of Pathology, HUSLAB, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Kytölä SI; HUS Diagnostic Center, HUSLAB, Helsinki University Hospital, Helsinki, Finland., Aittokallio TA; iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland.; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, and Oslo Centre for Biostatistics and Epidemiology, University of Oslo, Oslo, Norway., Ramos PM; Novartis Pharmaceuticals, Basel, Switzerland., Porkka KV; Hematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland.; Helsinki University Hospital Comprehensive Cancer Center, Department of Hematology, Helsinki, Finland., Mustjoki SM; Hematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland.; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.

Publikováno v: Blood cancer discovery [Blood Cancer Discov] 2021 Mar 22; Vol. 2 (3), pp. 238-249. Date of Electronic Publication: 2021 Mar 22 (Print Publication: 2021).