Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lalitha V, Ramanathapuram"'
Autor:
Emmanuel T. Akporiaye, Lalitha V. Ramanathapuram, Magdalena J. Polanczyk, Stephen John Ralph, T. Hahn, Alexandra Borodovsky
Publikováno v:
Current Pharmaceutical Biotechnology. 14:357-376
Cytotoxic drugs in cancer therapy are used with the expectation of selectively killing and thereby eliminating the offending cancer cells. If they should die in an appropriate manner, the cells can also release danger signals that promote an immune r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b89edc3fc3d47d8a6d3f7abf23e0ed
https://doi.org/10.2174/1389201011314030010
https://doi.org/10.2174/1389201011314030010
Autor:
Laurence H. Hurley, Lalitha V. Ramanathapuram, Lajos Szabo, Emmanuel T. Akporiaye, Mikhal Gold, Tobias Hahn
Publikováno v:
Cancer Research. 66:9374-9378
The ability of the vitamin E (RRR-α-tocopherol) derivatives α-tocopheryl succinate (α-TOS) and α-tocopheryloxyacetic acid (α-TEA) to suppress tumor growth in preclinical animal models has recently led to increased interest in their potential use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b523d83f71e79c13520a17575945a45
https://doi.org/10.1158/0008-5472.can-06-2403
https://doi.org/10.1158/0008-5472.can-06-2403
Autor:
Amy M. Fulton, James J. Kobie, David G. Besselsen, Lalitha V. Ramanathapuram, Edwin B. Walker, Sharon M. Dial, Tobias Hahn, Irene Alvarez, Emmanuel T. Akporiaye
Publikováno v:
International Journal of Cancer. 118:2220-2231
Cyclooxygenase-2 (COX-2) is a rate-limiting enzyme in the synthesis of prostaglandins. It is over-expressed in multiple cancers and has been associated with diminished tumor immunity. Dendritic cells (DCs) are considered candidates for cancer immunot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02755a388dd71b525c0b96718219f111
https://doi.org/10.1002/ijc.21616
https://doi.org/10.1002/ijc.21616
Publikováno v:
Nutrition and Cancer. 53:177-193
In this study, we evaluated the efficacy of vesiculated alpha-tocopheryl succinate (Valpha-TOS) in combination with non-antigen pulsed, nonmatured dendritic cells (nmDC) to treat pre-established tumors of the highly metastatic murine mammary cancer c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25dadc25a504f8fb6a08e87cf61a6064
https://doi.org/10.1207/s15327914nc5302_7
https://doi.org/10.1207/s15327914nc5302_7
Dendritic cells (DC) are considered potential candidates for cancer immunotherapy due to their ability to process and present antigens to T cells and stimulate immune responses. However, DC-based vaccines have exhibited minimal effectiveness in abrog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b03e2219be41a39756467082c0bab9c
https://doi.org/10.21236/ada429187
https://doi.org/10.21236/ada429187
Autor:
James J. Kobie, Emmanuel T. Akporiaye, Katrina T. Trevor, Claire M. Payne, David J. Bearss, Lalitha V. Ramanathapuram
Publikováno v:
Cancer immunology, immunotherapy : CII. 53(7)
Dendritic cells (DCs) are considered potential candidates for cancer immunotherapy due to their ability to process and present antigens to T cells and stimulate immune responses. However, DC-based vaccines have exhibited minimal effectiveness against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3f96da5e0d856efa4d97cb95ffa2d1
https://pubmed.ncbi.nlm.nih.gov/14991239
https://pubmed.ncbi.nlm.nih.gov/14991239
Autor:
James J, Kobie, Rita S, Wu, Robert A, Kurt, Sunming, Lou, Miranda K, Adelman, Luke J, Whitesell, Lalitha V, Ramanathapuram, Carlos L, Arteaga, Emmanuel T, Akporiaye
Publikováno v:
Cancer research. 63(8)
Dendritic cell (DC)-based vaccines have exhibited minimal effectiveness in treating established tumors, likely because of factors present in the tumor microenvironment. One such factor is transforming growth factor beta (TGF-beta), a cytokine that is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89cbc93481691ba25c554341f83defec
https://pubmed.ncbi.nlm.nih.gov/12702574
https://pubmed.ncbi.nlm.nih.gov/12702574
Publikováno v:
Journal of Immunotherapy. 27:S22-S23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53877f83848cfabc8ce310902097790b
https://doi.org/10.1097/00002371-200411000-00083
https://doi.org/10.1097/00002371-200411000-00083