Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lalitha Thiagarajan"'
Autor:
Stuart A. Lanham, Richard O.C. Oreffo, Mahetab H. Amer, Lalitha Thiagarajan, Robin M. H. Rumney, Hosam Al-Deen M. Abu Awwad, James E. Dixon, Gordon Bruce, Janos M. Kanczler
Publikováno v:
Journal of Controlled Release
Abu Awwad, H A-D, Thiagarajan, L, Kanczler, J, Amer, M, Bruce, G, Lanham, S, Rumney, R M H, Oreffo, R & Dixon, J 2020, ' Genetically-programmed, mesenchymal stromal cell-laden & mechanically strong 3D bioprinted scaffolds for bone repair ', Journal of Controlled Release: Official Journal of the Controlled Release Society, vol. 325, pp. 335-346 . https://doi.org/10.1016/j.jconrel.2020.06.035
Abu Awwad, H A-D, Thiagarajan, L, Kanczler, J, Amer, M, Bruce, G, Lanham, S, Rumney, R M H, Oreffo, R & Dixon, J 2020, ' Genetically-programmed, mesenchymal stromal cell-laden & mechanically strong 3D bioprinted scaffolds for bone repair ', Journal of Controlled Release: Official Journal of the Controlled Release Society, vol. 325, pp. 335-346 . https://doi.org/10.1016/j.jconrel.2020.06.035
Additive manufacturing processes used to create regenerative bone tissue engineered implants are not biocompatible, thereby restricting direct use with stem cells and usually require cell seeding post-fabrication. Combined delivery of stem cells with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bc885e77945d995a7465eeb25bc5a5
http://europepmc.org/articles/PMC7445425
http://europepmc.org/articles/PMC7445425
Autor:
Stuart A. Lanham, Janos M. Kanczler, Alexander P. Kao, James E. Dixon, Lalitha Thiagarajan, Robin M. H. Rumney, Gianluca Tozzi, Richard O.C. Oreffo
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Rumney, R M H, Tozzi, G, Kao, A, Lanham, S, Kanczler, J, Thiagarajan, L, Dixon, J & Oreffo, R 2019, ' In vivo delivery of VEGF RNA and protein to increase osteogenesis and intraosseous angiogenesis ', Scientific Reports, vol. 9, 17745 . https://doi.org/10.1038/s41598-019-53249-4
Scientific Reports
Rumney, R M H, Tozzi, G, Kao, A, Lanham, S, Kanczler, J, Thiagarajan, L, Dixon, J & Oreffo, R 2019, ' In vivo delivery of VEGF RNA and protein to increase osteogenesis and intraosseous angiogenesis ', Scientific Reports, vol. 9, 17745 . https://doi.org/10.1038/s41598-019-53249-4
Deficient bone vasculature is a key component in pathological conditions ranging from developmental skeletal abnormalities to impaired bone repair. Vascularisation is dependent upon vascular endothelial growth factor (VEGF), which drives both angioge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319727c16025372663f0b2fa50fdd25e
http://link.springer.com/article/10.1038/s41598-019-53249-4
http://link.springer.com/article/10.1038/s41598-019-53249-4
Autor:
Hans-Dietmar Beer, Maria Rosaria Mollo, Kristin Seltmann, Lalitha Thiagarajan, Caterina Missero, Paulina Hennig, Andreas Bachmann, Andreas Schwendimann, Svitlana Kurinna, Sabine Werner
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 49 (7)
Nucleic Acids Research, 49 (7)
Epigenetic regulation of cell and tissue function requires the coordinated action of transcription factors. However, their combinatorial activities during regeneration remain largely unexplored. Here, we discover an unexpected interaction between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91382d146843d3302b61fbcf549b330
http://hdl.handle.net/11588/880367
http://hdl.handle.net/11588/880367
Publikováno v:
Stem Cells Translational Medicine
Mesenchymal stem cells (MSCs) are being exploited in regenerative medicine due to their tri-lineage differentiation and immunomodulation activity. Currently, there are two major challenges when directing the differentiation of MSCs for therapeutic ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96395e53911a0cacd898ae71bd9aecae
https://nottingham-repository.worktribe.com/file/896796/1/Thiagarajan_et_al-2017-STEM_CELLS_Translational_Medicine.pdf
https://nottingham-repository.worktribe.com/file/896796/1/Thiagarajan_et_al-2017-STEM_CELLS_Translational_Medicine.pdf
Autor:
Xuan Xue, Lalitha Thiagarajan, Brian R. Saunders, Shwana Braim, Kevin M. Shakesheff, Cameron Alexander
Publikováno v:
Xue, X, Thiagarajan, L, Braim, S, Saunders, B R, Shakesheff, K M & Alexander, C 2017, ' Upper critical solution temperature thermo-responsive polymer brushes and a mechanism for controlled cell attachment ', Journal of Materials Chemistry B, vol. 5, no. 25, pp. 4926-4933 . https://doi.org/10.1039/c7tb00052a
We report the synthesis of thermo-responsive polymer brushes with Upper Critical Solution Temperature (UCST)-type behaviour on glass to provide a new means to control cell attachment. Thermoresponsive poly(N-acryloyl glycinamide)-stat-poly(N-phenylac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3dced7d1eb26a9e1a43d780838f32f
https://doi.org/10.1039/c7tb00052a
https://doi.org/10.1039/c7tb00052a
Publikováno v:
Acta biomaterialia. 57
Controlled release systems for therapeutic molecules are vital to allow the sustained local delivery of their activities which direct cell behaviour and enable novel regenerative strategies. Direct programming of cells using exogenously delivered tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e09babc4e1dc322f2963778736186f0
https://pubmed.ncbi.nlm.nih.gov/28457961
https://pubmed.ncbi.nlm.nih.gov/28457961
Autor:
Catherine A. Higgins, Richard D. Kennedy, Paul B. Mullan, James Murray, Gareth Irwin, Richard Williams, Karen D. McCloskey, Karl Mulligan, Denis Paul Harkin, Chee Wee Ong, David L. Boyle, Niamh E. Buckley, David Waugh, Manuel Salto-Tellez, Darragh G. McArt, Zenobia C. D’Costa, Nyree Crawford, Christopher J. Scott, Lalitha Thiagarajan
Publikováno v:
D'Costa, Z C, Higgins, C, Ong, C W, Irwin, G W, Boyle, D, McArt, D G, McCloskey, K, Buckley, N E, Crawford, N T, Thiagarajan, L, Murray, J T, Kennedy, R D, Mulligan, K A, Harkin, D P, Waugh, D J J, Scott, C J, Salto-Tellez, M, Williams, R & Mullan, P B 2014, ' TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities. ', Oncotarget, vol. 5, no. 6, pp. 1609-1620 . https://doi.org/10.18632/oncotarget.1707
Oncotarget
Oncotarget
// Zenobia C. D’Costa 1 , Catherine Higgins 1 , Chee Wee Ong 1 , Gareth W. Irwin 1 , David Boyle 1 , Darragh G. McArt 1 , Karen McCloskey 1 , Niamh E. Buckley 1 , Nyree T. Crawford 1 , Lalitha Thiagarajan 3 , James T. Murray 2 , Richard D. Kennedy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ce3ef7f94c25ef68a57b2b47b783b1
https://cronfa.swan.ac.uk/Record/cronfa56402
https://cronfa.swan.ac.uk/Record/cronfa56402