Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.

Autor: Perez-Bermejo JA; Graphite Bio, South San Francisco, CA, USA., Efagene O; Graphite Bio, South San Francisco, CA, USA., Matern WM; Graphite Bio, South San Francisco, CA, USA., Holden JK; Graphite Bio, South San Francisco, CA, USA., Kabir S; Graphite Bio, South San Francisco, CA, USA., Chew GM; Graphite Bio, South San Francisco, CA, USA., Andreoletti G; Graphite Bio, South San Francisco, CA, USA., Catton E; Graphite Bio, South San Francisco, CA, USA., Ennis CL; Graphite Bio, South San Francisco, CA, USA., Garcia A; Graphite Bio, South San Francisco, CA, USA., Gerstenberg TL; Graphite Bio, South San Francisco, CA, USA., Hill KA; Graphite Bio, South San Francisco, CA, USA., Jain A; Graphite Bio, South San Francisco, CA, USA., Krassovsky K; Graphite Bio, South San Francisco, CA, USA., Lalisan CD; Graphite Bio, South San Francisco, CA, USA., Lord D; Graphite Bio, South San Francisco, CA, USA., Quejarro BJ; Graphite Bio, South San Francisco, CA, USA., Sales-Lee J; Graphite Bio, South San Francisco, CA, USA., Shah M; Graphite Bio, South San Francisco, CA, USA., Silva BJ; Graphite Bio, South San Francisco, CA, USA., Skowronski J; Graphite Bio, South San Francisco, CA, USA., Strukov YG; Graphite Bio, South San Francisco, CA, USA., Thomas J; Graphite Bio, South San Francisco, CA, USA., Veraz M; Graphite Bio, South San Francisco, CA, USA., Vijay T; Graphite Bio, South San Francisco, CA, USA., Wallace KA; Graphite Bio, South San Francisco, CA, USA., Yuan Y; Graphite Bio, South San Francisco, CA, USA., Grogan JL; Graphite Bio, South San Francisco, CA, USA., Wienert B; Graphite Bio, South San Francisco, CA, USA., Lahiri P; Graphite Bio, South San Francisco, CA, USA., Treusch S; Graphite Bio, South San Francisco, CA, USA., Dever DP; Graphite Bio, South San Francisco, CA, USA., Soros VB; Graphite Bio, South San Francisco, CA, USA., Partridge JR; Graphite Bio, South San Francisco, CA, USA., Seim KL; Graphite Bio, South San Francisco, CA, USA. scicomms@graphitebio.com.

Publikováno v: Nature communications [Nat Commun] 2024 Mar 23; Vol. 15 (1), pp. 2625. Date of Electronic Publication: 2024 Mar 23.