Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Laleh Soltan Ghoraie"'
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The interactions between drugs and their target proteins induce altered expression of genes involved in complex intracellular networks. The properties of these functional network modules are critical for the identification of drug targets, for drug r
Externí odkaz:
https://doaj.org/article/f08a7d5305624ae492179f8326bf8db5
Autor:
Benjamin Haibe-Kains, Anna Goldenberg, Gary D. Bader, Ruth Isserlin, Chantal Ho, Erin Birkwood, Ailsa Fang, Kenan Deng, Christina Chung, Petr Smirnov, Zhaleh Safikhani, Laleh Soltan Ghoraie, Deena M.A. Gendoo, Nehme El-Hachem
Statistical comparison of the DNF taxonomy against single datasets taxonomies, using one-sided superiority tests
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5ae4dde6a801667b8d2e82a3d183f6
https://doi.org/10.1158/0008-5472.22413561.v1
https://doi.org/10.1158/0008-5472.22413561.v1
Autor:
Benjamin Haibe-Kains, Anna Goldenberg, Gary D. Bader, Ruth Isserlin, Chantal Ho, Erin Birkwood, Ailsa Fang, Kenan Deng, Christina Chung, Petr Smirnov, Zhaleh Safikhani, Laleh Soltan Ghoraie, Deena M.A. Gendoo, Nehme El-Hachem
Similarity Matrices of the DNF and single-layer taxonomies (based on the CTRPv2 drug sensitivity dataset).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a4f918cc4c398599d0c27c71eb02e4
https://doi.org/10.1158/0008-5472.22413564.v1
https://doi.org/10.1158/0008-5472.22413564.v1
Autor:
Benjamin Haibe-Kains, Anna Goldenberg, Gary D. Bader, Ruth Isserlin, Chantal Ho, Erin Birkwood, Ailsa Fang, Kenan Deng, Christina Chung, Petr Smirnov, Zhaleh Safikhani, Laleh Soltan Ghoraie, Deena M.A. Gendoo, Nehme El-Hachem
This file contains all the Supplementary Figures (1-9) reporting the results of DNF using the NCI60 drug sensitivity data, as well as additional information regarding the size and distribution for drug communities in the DNF taxonomies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8caf7b0f0f8a5bce9a0528556cacca4c
https://doi.org/10.1158/0008-5472.22413573
https://doi.org/10.1158/0008-5472.22413573
Autor:
Benjamin Haibe-Kains, Anna Goldenberg, Gary D. Bader, Ruth Isserlin, Chantal Ho, Erin Birkwood, Ailsa Fang, Kenan Deng, Christina Chung, Petr Smirnov, Zhaleh Safikhani, Laleh Soltan Ghoraie, Deena M.A. Gendoo, Nehme El-Hachem
Comparison of predictive value of DNF versus published methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc470d1bad4fed6c4390d8bd35951ce3
https://doi.org/10.1158/0008-5472.22413552.v1
https://doi.org/10.1158/0008-5472.22413552.v1
Autor:
Benjamin Haibe-Kains, Anna Goldenberg, Gary D. Bader, Ruth Isserlin, Chantal Ho, Erin Birkwood, Ailsa Fang, Kenan Deng, Christina Chung, Petr Smirnov, Zhaleh Safikhani, Laleh Soltan Ghoraie, Deena M.A. Gendoo, Nehme El-Hachem
Drug communities identified from the DNF taxonomies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d75b714077ab14a6995311b44aac063
https://doi.org/10.1158/0008-5472.22413558.v1
https://doi.org/10.1158/0008-5472.22413558.v1
Autor:
Benjamin Haibe-Kains, Anna Goldenberg, Gary D. Bader, Ruth Isserlin, Chantal Ho, Erin Birkwood, Ailsa Fang, Kenan Deng, Christina Chung, Petr Smirnov, Zhaleh Safikhani, Laleh Soltan Ghoraie, Deena M.A. Gendoo, Nehme El-Hachem
Identification of drug targets and mechanism of action (MoA) for new and uncharacterized anticancer drugs is important for optimization of treatment efficacy. Current MoA prediction largely relies on prior information including side effects, therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d39c0edc09101d413a869aa7d8008f38
https://doi.org/10.1158/0008-5472.c.6508752.v1
https://doi.org/10.1158/0008-5472.c.6508752.v1
Autor:
Benjamin Haibe-Kains, Anna Goldenberg, Gary D. Bader, Ruth Isserlin, Chantal Ho, Erin Birkwood, Ailsa Fang, Kenan Deng, Christina Chung, Petr Smirnov, Zhaleh Safikhani, Laleh Soltan Ghoraie, Deena M.A. Gendoo, Nehme El-Hachem
This file contains the legends for Supplementary Tables 1 to 5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee1e86fcfc4638d5f7b694ea15efa3e
https://doi.org/10.1158/0008-5472.22413549.v1
https://doi.org/10.1158/0008-5472.22413549.v1
Autor:
Benjamin Haibe-Kains, Anna Goldenberg, Gary D. Bader, Ruth Isserlin, Chantal Ho, Erin Birkwood, Ailsa Fang, Kenan Deng, Christina Chung, Petr Smirnov, Zhaleh Safikhani, Laleh Soltan Ghoraie, Deena M.A. Gendoo, Nehme El-Hachem
This file contains a detailed description of the methods used to reproduce published algorithms for drug clustering.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ba8c6dcc15c8d2836c681f8f778536
https://doi.org/10.1158/0008-5472.22413570
https://doi.org/10.1158/0008-5472.22413570
Autor:
Benjamin Haibe-Kains, Anna Goldenberg, Gary D. Bader, Ruth Isserlin, Chantal Ho, Erin Birkwood, Ailsa Fang, Kenan Deng, Christina Chung, Petr Smirnov, Zhaleh Safikhani, Laleh Soltan Ghoraie, Deena M.A. Gendoo, Nehme El-Hachem
Enrichment of DNF drug communities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdaf5c7305209682afd043da6049711
https://doi.org/10.1158/0008-5472.22413555.v1
https://doi.org/10.1158/0008-5472.22413555.v1