Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Laleh Abbassi"'
Autor:
Laleh Abbassi, Stephany El-Hayek, Karen Freire Carvalho, Wusu Wang, Qin Yang, Sofia Granados-Aparici, Rafael Mondadori, Vilceu Bordignon, Hugh J. Clarke
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Uncoupling of mature oocytes from somatic granulosa cells is required for their fertilization. Here the authors show that activation of EGFR signalling in granulosa cells during ovulation triggers ERK-dependent loss of filopodia oocyte adhesion, and
Externí odkaz:
https://doaj.org/article/348d0733017a4b4c8fcd9963a3acfe35
Autor:
Jimmy A. Guo, Jennifer Su, Carina Shiau, Ananya Jambhale, Annan Yang, Westley Wu, Junning Wang, Connor Hennessey, Patrick Yu, Brendan Parent, Giselle Uribe, Julien Dilly, Laleh Abbassi, Qijia Yu, Arnav Mehta, David Ting, Brian Wolpin, William Freed-Pastor, Joseph Mancias, Tyler Jacks, William L. Hwang, Andrew J. Aguirre
Publikováno v:
Cancer Research. 83:5775-5775
Pancreatic cancer is a challenging disease which lacks a robust precision oncology framework. Prior work has demonstrated that transcriptional subtypes in pancreatic cancer can stratify patients by response to chemotherapy and overall survival. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4d6029238aabeda3bd7aa388423b8cc
https://doi.org/10.1158/1538-7445.am2023-5775
https://doi.org/10.1158/1538-7445.am2023-5775
Autor:
Jimmy A. Guo, Jennifer Su, Ananya Jambhale, Julien Dilly, Connor J. Hennessey, Carina Shiau, Patrick Yu, Steven Wang, Junning Wang, Laleh Abbassi, James Neiswender, Tate Bertea, Annan Yang, Qijia Yu, Peter Westcott, Jason Schenkel, Daniel Y. Kim, Hannah I. Hoffman, Grissel Cervantes Jaramillo, Giselle A. Uribe, Westley W. Wu, Arnav Mehta, David Ting, Julian A. Pacheco, Amy Deik, Clary Clish, Francisca Vazquez, Brian Wolpin, Aviv Regev, William A. Freed-Pastor, Joseph D. Mancias, Tyler Jacks, William L. Hwang, Andrew J. Aguirre
Publikováno v:
Cancer Research. 82:A052-A052
Transcriptional states in pancreatic cancer can stratify patients by response to chemotherapy and clinical outcomes. These include the classical and basal-like states as well as a newly identified neural-like progenitor (NRP) state, which we have pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c57b339736547811fae95da2bf956e5f
https://doi.org/10.1158/1538-7445.panca22-a052
https://doi.org/10.1158/1538-7445.panca22-a052
Autor:
Wusu Wang, Stephany El-Hayek, Hugh J. Clarke, Sofia Granados-Aparici, Qin Yang, Rafael Gianella Mondadori, Laleh Abbassi, Karen Freire Carvalho, Vilceu Bordignon
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Germ cells are physically coupled to somatic support cells of the gonad during differentiation, but this coupling must be disrupted when they are mature, freeing them to participate in fertilization. In mammalian females, coupling occurs via speciali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7a5554ff740daa1ff527d7ffd5761d
https://doi.org/10.1038/s41467-021-21644-z
https://doi.org/10.1038/s41467-021-21644-z
Autor:
Janet Rossant, Angus D. Macaulay, Laleh Abbassi, Katie Cockburn, Claude Robert, Safia Malki, Hugh J. Clarke
Publikováno v:
Biology of Reproduction. 94
Reproduction depends on the generation of healthy oocytes. Improving therapeutic strategies to prolong or rescue fertility depends on identifying the inter- and intracellular mechanisms that direct oocyte development under physiological conditions. G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e55f40eafb797cc352b1ea2fd7c44ec
https://doi.org/10.1095/biolreprod.115.137968
https://doi.org/10.1095/biolreprod.115.137968