Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Laleh, Melstrom"'
Autor:
Meilin Xue, Lei Dong, Honghai Zhang, Yangchan Li, Kangqiang Qiu, Zhicong Zhao, Min Gao, Li Han, Anthony K. N. Chan, Wei Li, Keith Leung, Kitty Wang, Sheela Pangeni Pokharel, Ying Qing, Wei Liu, Xueer Wang, Lili Ren, Hongjie Bi, Lu Yang, Chao Shen, Zhenhua Chen, Laleh Melstrom, Hongzhi Li, Nikolai Timchenko, Xiaolan Deng, Wendong Huang, Steven T. Rosen, Jingyan Tian, Lin Xu, Jiajie Diao, Chun-Wei Chen, Jianjun Chen, Baiyong Shen, Hao Chen, Rui Su
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-24 (2024)
Abstract Background While liver cancer stem cells (CSCs) play a crucial role in hepatocellular carcinoma (HCC) initiation, progression, recurrence, and treatment resistance, the mechanism underlying liver CSC self-renewal remains elusive. We aim to c
Externí odkaz:
https://doaj.org/article/b8cac747695b48e59f1516ff7bd9a5a7
Autor:
Qianqian Zhao, Adrian Kohut, Yi-Jia Li, Antons Martincuks, Theresa Austria, Chunyan Zhang, Nicole Lugo Santiago, Rosemarie Martinez Borrero, Xuan Thuy Phan, Laleh Melstrom, Lorna Rodriguez-Rodriguez, Hua Yu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Recently, poly(ADP-ribosyl)ation polymerase inhibitors (PARPis), which induce synthetic lethality of tumor cells with DNA damage repair defects, have emerged as a promising therapy for ovarian, breast, and pancreatic cancer. Although the PARPi Olapar
Externí odkaz:
https://doaj.org/article/39c14fa5669444e889ed0d1e0d5c327b
Autor:
Mustafa Raoof, Zeljka Jutric, Sidra Haye, Philip H. G. Ituarte, Beiqun Zhao, Gagandeep Singh, Laleh Melstrom, Susanne G. Warner, Bryan Clary, Yuman Fong
Publikováno v:
Cancer Medicine, Vol 9, Iss 17, Pp 6256-6267 (2020)
Abstract Background Despite evidence that liver resection improves survival in patients with colorectal cancer liver metastases (CRCLM) and may be potentially curative, there are no population‐level data examining utilization and predictors of live
Externí odkaz:
https://doaj.org/article/8323b49bb0634f3a803f847c347ede1c
Autor:
Colt A. Egelston, Weihua Guo, Jiayi Tan, Christian Avalos, Diana L. Simons, Min Hui Lim, Yinghui J. Huang, Michael S. Nelson, Arnab Chowdhury, Daniel B. Schmolze, John H. Yim, Laura Kruper, Laleh Melstrom, Kim Margolin, Joanne E. Mortimer, Yuan Yuan, James R. Waisman, Peter P. Lee
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
CD8+ tumor-infiltrating lymphocytes (TILs) are associated with improved survival in triple-negative breast cancer (TNBC) yet have no association with survival in estrogen receptor–positive (ER+) BC. The basis for these contrasting findings remains
Externí odkaz:
https://doaj.org/article/71630b8f86fc4c07b75223a29542c6d2
Autor:
Colt A. Egelston, Christian Avalos, Travis Y. Tu, Diana L. Simons, Grecia Jimenez, Jae Y. Jung, Laleh Melstrom, Kim Margolin, John H. Yim, Laura Kruper, Joanne Mortimer, Peter P. Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Expression of the checkpoint molecule programmed cell death protein 1 (PD-1) is considered a marker of T cells exhaustion. Here the authors show that CD8T cells isolated from breast cancer patients are perfectly functional despite PD-1 expression whi
Externí odkaz:
https://doaj.org/article/ef04fd0226fd442ea943ccda7d8a10a5
Autor:
Gautam Malhotra, Kelly Lafaro, Ioannis Konstantinidis, Laleh Melstrom, Mark Hannah, Lily Lai, Kurt Melstrom, Steven Sentovich, Andreas Kaiser, Isaac B. Paz, Mustafa Raoof
Publikováno v:
Journal of Surgical Oncology. 127:657-667
T4 colon cancers have been underrepresented in randomized trials comparing minimally invasive colectomy (MC) versus open colectomy (OC). Retrospective studies suggest improved survival with MC versus OC, but have not addressed the impact of tumor ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08456be9595b6dfb5e0842e943ebd042
https://doi.org/10.1002/jso.27162
https://doi.org/10.1002/jso.27162
Autor:
Thuy B, Tran, Gautam, Malhotra, Marianne, Razavi, Karen, Clark, Matthew, Loscalzo, Laura, Kruper, Mustafa, Raoof, Yanghee, Woo, Vijay, Trisal, Yuman, Fong, Laleh, Melstrom
Publikováno v:
Annals of Surgery. 276:694-700
There has been an alarming increase in the number of young adults (YA) diagnosed with cancer. The emotional, psychosocial, and financial distress experienced by newly diagnosed YA undergoing cancer surgery remains largely unknown.A validated biopsych
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759b6829bd6ebf26e0793f2267a537af
https://doi.org/10.1097/sla.0000000000005593
https://doi.org/10.1097/sla.0000000000005593
Autor:
Gautam K Malhotra, Thuy Tran, Camille Stewart, Hannah Battey, Bernard Tegtmeier, Kathy McNeese, Annemarie Flood, Laleh Melstrom, Yuman Fong
Publikováno v:
Journal of the American College of Surgeons. 234:571-578
The coronavirus disease 2019 (COVID-19) pandemic created shortages of operating room (OR) supplies, forcing healthcare systems to make concessions regarding "standard" OR attire. At our institution, we were required to reduce shoe covers, reuse face
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9aaf8a437dbbe6a60d0123c7ad9723
https://doi.org/10.1097/xcs.0000000000000087
https://doi.org/10.1097/xcs.0000000000000087
Autor:
Louisa Liu, Yanghee Woo, Massimo D’Apuzzo, Laleh Melstrom, Mustafa Raoof, Yu Liang, Michelle Afkhami, Stanley R. Hamilton, Joseph Chao
Publikováno v:
Journal of the National Comprehensive Cancer Network : JNCCN. 20(8)
Despite the use of first-line therapies like fluoropyrimidine and platinum-based cytotoxic chemotherapy, gastric cancer (GC) continues to carry a poor prognosis. Recent subgroup analyses of first-line phase III trials have demonstrated that patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab9879075863c0829e13eca04d11f3b
https://pubmed.ncbi.nlm.nih.gov/35948034
https://pubmed.ncbi.nlm.nih.gov/35948034
Autor:
Sumana Narayanan, Georg Herlitz, Daniela Gomez, Laleh Melstrom, David A. August, Darren R. Carpizo
Publikováno v:
Surgical Techniques Development, Vol 5, Iss 1 (2015)
Oncologic resections of the second and third portions of the duodenum (D2 and D3) via partial duodenectomy can pose a challenging clinical problem. The duodenum must be repaired primarily or reconstructed. We have adopted a method of reconstruction u
Externí odkaz:
https://doaj.org/article/4909f7a6361e4579a82809f9fa2d4986