Mikania micrantha silver nanoparticles exhibit anticancer activities against human lung adenocarcinoma via caspase-mediated apoptotic cell death

Autor: Fanai Lalsangpuii, Samuel Lalthazuala Rokhum, Fanai Nghakliana, Joseph V. L. Ruatpuia, Lalchhandami Tochhawng, Amit Kumar Trivedi, Ralte Lalfakzuala, Zothan Siama

Publikováno v: Artificial Cells, Nanomedicine, and Biotechnology, Vol 52, Iss 1, Pp 186-200 (2024)

AbstractGreen-mediated synthesis of nanoparticles has earned a promising role in the area of nanotechnology due to their biomedical applications. This study describes the synthesis of silver nanoparticles (AgNPs) using Mikania micrantha leaf extract

Externí odkaz: https://doaj.org/article/94ee0485542549d29e09d1465b57a21e

Mussaenda macrophylla Wall. exhibit anticancer activity against Dalton’s lymphoma ascites (DLA) bearing mice via alterations of redox-homeostasis and apoptotic genes expression

Autor: Marina Lalremruati, C. Lalmuansangi, Mary Zosangzuali, Lalchhandami Tochhawng, Amit Kumar Trivedi, Nachimuthu Senthil Kumar, Zothan Siama

Publikováno v: Journal of Basic and Applied Zoology, Vol 83, Iss 1, Pp 1-14 (2022)

Abstract Background Mussaenda macrophylla is a shrub widely used in Mizo traditional practice for treatment of cancer, fever, cough, ulcer and dysentery. We have previously shown the antioxidant nature of the plant. In this study, we explore the anti

Externí odkaz: https://doaj.org/article/0094d4e673a84882a82bc1400743d5a3

Evaluation of the protective effects of

Autor: C, Lalmuansangi, Mary, Zosangzuali, Marina, Lalremruati, Lalchhandami, Tochhawng, Zothan, Siama

Publikováno v: Drug and chemical toxicology. 45(3)

The toxic side effects of doxorubicin in cancer treatment are well established. Here we show that methanolic extract of the fungus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::55ed9f6223915582c31735ce8a05ce39
https://pubmed.ncbi.nlm.nih.gov/32854544

Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion

Autor: Lalchhandami Tochhawng, Shuo Deng, Ganesan Pugalenthi, Alan Prem Kumar, Kiat Hon Lim, Tuan Zea Tan, Henry Yang, Shing Chuan Hooi, Yaw Chong Goh, Sutherland K. Maciver, Shazib Pervaiz, Celestial T. Yap

Publikováno v: Oncotarget
Tochhawng, L, Deng, S, Pugalenthi, G, Kumar, A P, Lim, K H, Yang, H, Hooi, S C, Goh, Y C, Maciver, S K, Pervaiz, S & Yap, C T 2016, ' Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion ', Oncotarget . https://doi.org/10.18632/oncotarget.10451

// Lalchhandami Tochhawng 1 , Shuo Deng 1 , Ganesan Pugalenthi 3 , Alan Prem Kumar 2,4,5,6,7 , Kiat Hon Lim 8 , Tuan Zea Tan 4 , Henry Yang 4 , Shing Chuan Hooi 1 , Yaw Chong Goh 9,10 , Sutherland K. Maciver 11 , Shazib Pervaiz 1,12,13,14 and Celesti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349905c5b592f3445bbb1ecc4bc63bcc
http://europepmc.org/articles/PMC5288152

Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade

Autor: Shing Chuan Hooi, Jingli Zhuo, Ee Hong Tan, Hwee Kee Tay, Sutherland K. Maciver, Celestial T. Yap, Manikandan Jayapal, Benedict Yan, S. Koh, Manuel Salto-Tellez, Lalchhandami Tochhawng, Yaw Chong Goh, Yaw Chyn Lim, Alan Prem Kumar

Publikováno v: Zhuo, J, Tan, E H, Yan, B, Tochhawng, L, Jayapal, M, Koh, S, Tay, H K, Maciver, S K, Hooi, S C, Salto-Tellez, M, Kumar, A P, Goh, Y C, Lim, Y C & Yap, C T 2012, ' Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade ', PLoS ONE, vol. 7, no. 8, pp. e43594 . https://doi.org/10.1371/journal.pone.0043594
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e43594 (2012)

Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fb96b5efea8f96443fe273ed0cd6cf
https://hdl.handle.net/20.500.11820/222c8d84-e800-421d-b564-2263ef06a29e