Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lakyn, Mayo"'
Autor:
Connor Stashko, Mary-Kate Hayward, Jason J. Northey, Neil Pearson, Alastair J. Ironside, Johnathon N. Lakins, Roger Oria, Marie-Anne Goyette, Lakyn Mayo, Hege G. Russnes, E. Shelley Hwang, Matthew L. Kutys, Kornelia Polyak, Valerie M. Weaver
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Intratumor heterogeneity associates with poor patient outcome. Stromal stiffening also accompanies cancer. Whether cancers demonstrate stiffness heterogeneity, and if this is linked to tumor cell heterogeneity remains unclear. We developed a
Externí odkaz:
https://doaj.org/article/8eef1f697e6d46898510e81e54f4c1d8
Autor:
Lakyn Mayo, Matthew Kutys
Publikováno v:
American Journal of Physiology-Cell Physiology. 323:C1333-C1344
Tumor metastasis via the circulation requires crossing the vascular barrier twice: first, during intravasation when tumor cells disseminate from the primary site through proximal vasculature, and second, during extravasation, when tumor cells exit th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ae5967047a696c3e09a25880535c9b
https://doi.org/10.1152/ajpcell.00173.2022
https://doi.org/10.1152/ajpcell.00173.2022
Autor:
Valerie Weaver, Connor Stashko, Mary-Kate Hayward, Jason Northey, Neil Pearson, Alastair Ironside, Johnathon Lakins, Marie-Anne Goyette, Lakyn Mayo, Hege Russnes, E Hwang, Matthew Kutys, Kornelia Polyak
Intratumor heterogeneity in breast cancer associates with poor patient outcome. Tissue fibrosis and stromal stiffening accompany breast cancer development and associate with the aggressiveness of human breast cancer subtypes. Whether human breast can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db134abffa10478a1d26b8ee2870df83
https://doi.org/10.21203/rs.3.rs-2063113/v1
https://doi.org/10.21203/rs.3.rs-2063113/v1
Autor:
Lakyn Mayo, Osamah Saeedi, Ginger Thompson, Julian Weichsel, Sachin Kalarn, Michael T. Ou, Victoria Chen, Lily Im, Joby Tsai, Anja Jones, Taariq K. Mohammed, Breanna Tracey, Mona Kaleem, Khelly Shah, Jiaqi Li, Christopher Le, Isa Mohammed, Luke Y. Chang, Corinne Renner
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Changes in retinal blood flow may be involved in the pathogenesis of glaucoma and other ocular diseases. Erythrocyte mediated velocimetry (EMV) is a novel technique where indocyanine green (ICG) dye is sequestered in erythrocyte ghosts and autologous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bed6561e3e64061b3da55b266b2cf79
http://link.springer.com/article/10.1038/s41598-019-56239-8
http://link.springer.com/article/10.1038/s41598-019-56239-8
Publikováno v:
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-12 (2018)
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS
Background Transwell-based models of the blood–brain barrier (BBB) incorporating monolayers of human brain microvascular endothelial cells (dhBMECs) derived from induced pluripotent stem cells show many of the key features of the BBB, including exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b7e12733581d732a92cbf39a6be5d5
http://link.springer.com/article/10.1186/s12987-018-0092-7
http://link.springer.com/article/10.1186/s12987-018-0092-7
Autor:
Lakyn Mayo, Vasiliki Mahairaki, Jeffrey D. Rothstein, Linzhao Cheng, Moriah E. Katt, Shannon E. Ellis, Peter C. Searson
Publikováno v:
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS, Vol 16, Iss 1, Pp 1-13 (2019)
Fluids and Barriers of the CNS, Vol 16, Iss 1, Pp 1-13 (2019)
Background Blood–brain barrier dysfunction is associated with many late-stage neurodegenerative diseases. An emerging question is whether the mutations associated with neurodegenerative diseases can independently lead to blood–brain barrier (BBB)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95d2385f9bf374c788b645c44725bae
https://doi.org/10.1186/s12987-019-0139-4
https://doi.org/10.1186/s12987-019-0139-4
Autor:
Katt, Moriah, Lakyn Mayo, Ellis, Shannon, Mahairaki, Vasiliki, Rothstein, Jeffrey, Linzhao Cheng, Searson, Peter
Additional file 1: Figure S1. Phase images of differentiation of iPSCs. Figure S2. Western blots. Figure S3. Expression of individual proteins and genes across all disease lines. Figure S4. Protein and gene expression by disease. Figure S5. Gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781e77e8c577ecde1d40afa4e45b8438
Additional file 1. Supplementary information, containing description of junctional width measurement, 2D adhesion assay, representative TEER values, and cell area on collgen I and glass substrates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f82a43025e9bde1b9aac5656df1a403
Autor:
Thomas, Pauwelyn, Richard, Stahl, Lakyn, Mayo, Xuan, Zheng, Andy, Lambrechts, Stefan, Janssens, Liesbet, Lagae, Veerle, Reumers, Dries, Braeken
Publikováno v:
Biomedical optics express. 9(4)
The high rate of drug attrition caused by cardiotoxicity is a major challenge for drug development. Here, we developed a reflective lens-free imaging (RLFI) approach to non-invasively record in vitro cell deformation in cardiac monolayers with high t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77da91396395721a0f3f1392e6e68804
https://pubmed.ncbi.nlm.nih.gov/29675322
https://pubmed.ncbi.nlm.nih.gov/29675322
Publikováno v:
Biomedical Optics Express. 10:3681
Retinal blood flow is an emerging biomarker in ocular and systemic disease. Erythrocyte mediated angiography (EMA) is a novel technique that provides an easily interpretable blood flow velocity quantification by directly tracing individual moving ery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c606fffb703ab4ff538bc68d03b3f2ea
https://doi.org/10.1364/boe.10.003681
https://doi.org/10.1364/boe.10.003681