Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lakshmi Rambhatla"'
Publikováno v:
Cell Transplantation, Vol 12 (2003)
Use of human hepatocytes for therapeutic and drug discovery applications is hampered by limited tissue source and the inability of hepatocytes to proliferate and maintain function long term in vitro. Human embryonic stem (hES) cells are immortal and
Externí odkaz:
https://doaj.org/article/be6152f4e1f3427dad4933c7c0047fd7
Publikováno v:
Cancer Research. 65:3155-3161
Because they are long-lived and cycle continuously, adult stem cells (ASCs) are predicted as the most common precursor for cancers in adult mammalian tissues. Two unique attributes have been proposed to restrict the carcinogenic potential of ASCs. Th
Autor:
Lakshmi Rambhatla, Keith E. Latham
Publikováno v:
Molecular Reproduction and Development. 41:16-19
Mouse embryos produced by the fertilization of eggs from (B6D2)F1 and CF-1 mice differ in their ability to complete the second cell cycle in the presence of α-amanitin. Essentially all embryos obtained from CF-1 mothers arrest at the two-cell stage
Publikováno v:
Developmental Biology. 168(2):670-676
The mouse U2afbp-rs gene is imprinted and expressed exclusively from the paternal allele in the adult. To determine whether the U2afbp-rs gene is regulated by imprinting in the early embryo and to examine its normal temporal pattern of expression, we
Autor:
Keith E. Latham, Lakshmi Rambhatla
Publikováno v:
Developmental Genetics. 17:212-222
A quantitative RT-PCR approach has been used to examine the expression of a number of X-linked genes during preimplantation development of normal mouse embryos and in androgenetic and gynogenetic mouse embryos. The data reveal moderately reduced expr
Publikováno v:
Investigative ophthalmologyvisual science. 43(5)
To investigate conditions promoting the differentiation of cultured human retinal pigment epithelial (RPE) cells and assess the differentiation potential of telomerase-immortalized RPE cells.Serially passaged RPE 340 (parental) cells have limited rep
Autor:
Patrizia B. Stadler, Jonathan T. Boyd, Shirley A. Bohn, Lakshmi Rambhatla, James L. Sherley, Ronald A. Coss
Publikováno v:
Hindawi Publishing Corporation
Journal of Biomedicine and Biotechnology, Vol 1, Iss 1, Pp 28-37 (2001)
Journal of Biomedicine and Biotechnology
Journal of Biomedicine and Biotechnology, Vol 1, Iss 1, Pp 28-37 (2001)
Journal of Biomedicine and Biotechnology
Although senescence is a defining property of euploid mammalian cells, its physiologic basis remains obscure. Previously, cell kinetics properties of normal tissue cells have not been considered in models for senescence. We now provide evidence that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0009b21e7bae4bba6c31ab82c3d4b2
http://hdl.handle.net/1721.1/96231
http://hdl.handle.net/1721.1/96231
Publikováno v:
Molecular reproduction and development. 41(3)
We have developed a novel reverse transcription-polymerase chain reaction (RT-PCR)-based approach for systematically quantifying in a single experiment the abundances of many different mRNAs in preimplantation mouse embryos. With this approach, the e