Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lakshmi R Perumalsamy"'
Autor:
Hemashree Golla, Adithi Kannan, Soundhararajan Gopi, Sowmiya Murugan, Lakshmi R Perumalsamy, Athi N. Naganathan
Publikováno v:
ACS Central Science, Vol 8, Iss 2, Pp 282-293 (2022)
Externí odkaz:
https://doaj.org/article/e0bd2656d195480b9145618d7434a801
Autor:
Soumya Gupta, Nimi Marcel, Shefali Talwar, Megha Garg, Indulaxmi R, Lakshmi R Perumalsamy, Apurva Sarin, G V Shivashankar
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43718 (2012)
Cellular differentiation programs are accompanied by large-scale changes in nuclear organization and gene expression. In this context, accompanying transitions in chromatin assembly that facilitates changes in gene expression and cell behavior in a d
Externí odkaz:
https://doaj.org/article/29e79660bab74c49ad89859806a1c9c4
Autor:
Sherine Joanna Fredrick, Tapasya K, Sanjana Rajgopal, Lakshmi R. Perumalsamy, Arun Dharmarajan
Publikováno v:
Handbook of Oxidative Stress in Cancer: Mechanistic Aspects ISBN: 9789811545016
Handbook of Oxidative Stress in Cancer: Mechanistic Aspects
Handbook of Oxidative Stress in Cancer: Mechanistic Aspects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf681521e2e139672626403ee23ece3c
https://doi.org/10.1007/978-981-15-9411-3_176
https://doi.org/10.1007/978-981-15-9411-3_176
Autor:
Krithicaa Narayanaa Y., Naveen Kumar Perumalsamy, Sudha Warrier, Lakshmi R. Perumalsamy, Arun Dharmarajan
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 145:106191
Ovarian cancer is a fatal malignancy in women with a low survival rate that demands new therapeutic paradigms. Cancer cells acquire various exclusive alterations to proliferate, invade, metastasize, and escape cell death, acting independently of grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89258735764a9c31ed49e5e52aa0be47
https://doi.org/10.1016/j.biocel.2022.106191
https://doi.org/10.1016/j.biocel.2022.106191
Autor:
Lakshmi R. Perumalsamy, M. Michael Gromiha, Chandrasekaran Ramakrishnan, Krishnaraj Rajalingam, Ananthi Sivagnanam, Pavitra Desai, Sundarasamy Mahalingam, Anitha Mamidi, Anbarasu Kumaraswamy
Publikováno v:
Journal of Biological Chemistry. 293:15691-15705
c-Myc is a proto-oncogene controlling expression of multiple genes involved in cell growth and differentiation. Although the functional role of c-Myc as a transcriptional regulator has been intensively studied, targeting this protein in cancer remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e9bc1f1bbf87253ce8933c6ee3e76e
https://doi.org/10.1074/jbc.ra118.004452
https://doi.org/10.1074/jbc.ra118.004452
Publikováno v:
Science signaling. 10(473)
The ability to tune cellular functions in response to nutrient availability has important consequences for immune homeostasis. The activity of the receptor Notch in regulatory T (Treg) cells, which suppress the functions of effector T cells, is indis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53f0093d700f5e9a74e1a65eb47640c
https://pubmed.ncbi.nlm.nih.gov/28377411
https://pubmed.ncbi.nlm.nih.gov/28377411
Publikováno v:
Proceedings of the National Academy of Sciences. 107:6882-6887
Survival of differentiated cells is one of several processes regulated by Notch activity, although the general principles underlying this function remain to be characterized. Here, we probe the mechanism underlying Notch-mediated survival, building o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ca2b0c1f2a2f059946010453a98165
https://doi.org/10.1073/pnas.0910060107
https://doi.org/10.1073/pnas.0910060107
Publikováno v:
International Journal of Cell Biology
International Journal of Cell Biology, Vol 2014 (2014)
International Journal of Cell Biology, Vol 2014 (2014)
Tissue homeostasis is a dynamic process involving proliferation and the removal of redundant or damaged cells. This is exemplified in the coordinated deletion - triggered by limiting trophic factors/cytokines in the extracellular milieu - of differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4105343b6e4f396c87f08619c227598d
http://europepmc.org/articles/PMC3943393
http://europepmc.org/articles/PMC3943393
Publikováno v:
Cancer Research. 76:5076-5076
Tumor metastasis, the spread of tumor cells to distant tissues from its site of initiation is a multi-step and multi-factorial process. Hyperactivation of RAS pathway is reported in >50% of different cancers and is associated with metastasis and poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09ff7f47e8e66047b447a62952307546
https://doi.org/10.1158/1538-7445.am2016-5076
https://doi.org/10.1158/1538-7445.am2016-5076
Publikováno v:
Sciencesignaling
Variations in the spatial localization of signaling components and crosstalk among signaling cascades are mechanisms through which diversity in signaling networks is generated. The receptor Notch provides an example of regulation by spatial localizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36c19a605c4c11523daae79c0041c79
https://pubmed.ncbi.nlm.nih.gov/22827997
https://pubmed.ncbi.nlm.nih.gov/22827997