Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Lakshmi Kanth Kotarkonda"'
5
ALTERATION OF AKT1-GSK3Β SIGNALING PATHWAY IN TRAUMA HEMORRHAGIC SHOCK PATIENTS
Autor: Lakshmi Kanth Kotarkonda, Subhashini Bharathala, Tej Prakash Sinha, Kapil Dev Soni, Richa Aggarwal, Arul Selvi, D N Rao, Ashok Sharma, Sanjeev Bhoi
Publikováno v: Shock (Augusta, Ga.). 58(6)
Trauma hemorrhagic shock (THS) is a major cause of death and disability worldwide. It is the leading cause of death with or without sepsis in approximately 50% of patients. In THS, there is an incidence of cellular apoptosis, which contributes majorl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2699f5974af9fd509498575fe0e583
https://pubmed.ncbi.nlm.nih.gov/36548639
Zobrazit plný text záznamu
6
Transforming Growth Factor-β1 Regulates Peroxisomal Genes/Proteins via Smad Signaling in Idiopathic Pulmonary Fibrosis Fibroblasts and Transgenic Mouse Models
Autor: Gani Oruqaj, Srikanth Karnati, Lakshmi Kanth Kotarkonda, Eistine Boateng, Marek Bartkuhn, Wenming Zhang, Clemens Ruppert, Andreas Günther, Laurent Bartholin, Wei Shi, Eveline Baumgart-Vogt
Publikováno v: The American journal of pathology.
Idiopathic pulmonary fibrosis (IPF) is a chronic human disease with persistent destruction of lung parenchyma. A pivotal role in the initiation and pathogenesis of IPF is played by transforming growth factor (TGF)-β1 signaling. As shown herein, TGF-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42de3c1824223fcc59aa27ae1b186815
https://pubmed.ncbi.nlm.nih.gov/36521562
Zobrazit plný text záznamu
7
In silico and experimental studies of bovine serum albumin-encapsulated carbenoxolone nanoparticles with reduced cytotoxicity
Autor: Pankaj Sharma, Vijay Pal Singh, Lakshmi Kanth Kotarkonda, Rajni Singh, Subhashini Bharathala
Publikováno v: Colloids and Surfaces B: Biointerfaces. 202:111670
Carbenoxolone (CBX) is a semi-synthetic plant derivative with pleiotropic pharmacological properties like anti-microbial and anti-inflammatory activities. Though approved for treatment of gastric ulcers, its use is limited due to adverse effects such
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772c1e81073010d8d42faec7245c0d41
https://doi.org/10.1016/j.colsurfb.2021.111670
Zobrazit plný text záznamu
8
Role of insulin like growth factor axis in the bleomycin induced lung injury in rats
Autor: K. Ravi, Lakshmi Kanth Kotarkonda, Ritu Kulshrestha
Publikováno v: Experimental and molecular pathology. 102(1)
Background Alveolar epithelial cell injury has been proposed as a causative factor for the onset and progression of pulmonary fibrosis. However, the role of type II alveolar epithelial cells (AECs) in the epithelial mesenchymal transition (EMT) is co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ac223ffefbb9108c82f63266c41798
https://pubmed.ncbi.nlm.nih.gov/28077319
Zobrazit plný text záznamu
9
Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling
Autor: Wenming Zhang, Clemens Ruppert, Andreas Günther, Eistine Boateng, Gani Oruqaj, Vijith Vijayan, Eveline Baumgart-Vogt, Lakshmi Kanth Kotarkonda, Wei Shi, Srikanth Karnati
Publikováno v: Proceedings of the National Academy of Sciences. 112
Idiopathic pulmonary fibrosis (IPF) is a devastating disease, and its pathogenic mechanisms remain incompletely understood. Peroxisomes are known to be important in ROS and proinflammatory lipid degradation, and their deficiency induces liver fibrosi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d9f556abfaa86ad41b8311312a15cc
https://doi.org/10.1073/pnas.1415111112
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje