Zobrazeno 1 - 10
of 308
pro vyhledávání: '"Lakshmi A Devi"'
Publikováno v:
eLife, Vol 10 (2021)
Many signal transduction systems have an apparent redundancy built into them, where multiple physiological agonists activate the same receptors. Whether this is true redundancy, or whether this provides an as-yet unrecognized specificity in downstrea
Externí odkaz:
https://doaj.org/article/3d0d23663e8e4701b7daae6d9fe62f91
Autor:
Andrea S Heimann, Achla Gupta, Ivone Gomes, Rayees Rahman, Avner Schlessinger, Emer S Ferro, Ellen M Unterwald, Lakshmi A Devi
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193322 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0187306.].
Externí odkaz:
https://doaj.org/article/a4558e9d7a874c83a917827c4a4bba35
Autor:
Andrea S Heimann, Achla Gupta, Ivone Gomes, Rahman Rayees, Avner Schlessinger, Emer S Ferro, Ellen M Unterwald, Lakshmi A Devi
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187306 (2017)
The N-terminal region of G protein-coupled receptors can be efficiently targeted for the generation of receptor-selective antibodies. These antibodies are useful for the biochemical characterization of the receptors. In this study, we developed a set
Externí odkaz:
https://doaj.org/article/a02462ed03164899bafd13870378401e
Autor:
Juan C. Sáez, Justin C. Burrell, Catherine M. Cahill, D. Kacy Cullen, Lakshmi A. Devi, Ryan J. Gilbert, Zachary A. Graham, Vadim J. Gurvich, Leif A. Havton, Ravi Iyengar, Rajesh Khanna, Edmund F. Palermo, Mustafa Siddiq, Carlos A. Toro, Walter Vasquez, Wei Zhao, Christopher P. Cardozo
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Over the past decade, boldine, a naturally occurring alkaloid found in several plant species including the Chilean Boldo tree, has garnered attention for its efficacy in rodent models of human disease. Some of the properties that have been attributed
Externí odkaz:
https://doaj.org/article/07edf235e1324a7b9a58860ef7edcbde
Autor:
Cristina Maria Costantino, Achla Gupta, Alice W Yewdall, Benjamin M Dale, Lakshmi A Devi, Benjamin K Chen
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33961 (2012)
Agents that activate cannabinoid receptor pathways have been tested as treatments for cachexia, nausea or neuropathic pain in HIV-1/AIDS patients. The cannabinoid receptors (CB(1)R and CB(2)R) and the HIV-1 co-receptors, CCR5 and CXCR4, all signal vi
Externí odkaz:
https://doaj.org/article/872c63a286b44497a740ab34586757bd
Autor:
Raphael Rozenfeld, Ittai Bushlin, Ivone Gomes, Nikos Tzavaras, Achla Gupta, Susana Neves, Lorenzo Battini, G Luca Gusella, Alexander Lachmann, Avi Ma'ayan, Robert D Blitzer, Lakshmi A Devi
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29239 (2012)
A fundamental question in G protein coupled receptor biology is how a single ligand acting at a specific receptor is able to induce a range of signaling that results in a variety of physiological responses. We focused on Type 1 cannabinoid receptor (
Externí odkaz:
https://doaj.org/article/dfa7832ff1064c5eb014bba50380be21
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e49789 (2012)
The diversity of receptor signaling is increased by receptor heteromerization leading to dynamic regulation of receptor function. While a number of studies have demonstrated that family A G-protein-coupled receptors are capable of forming heteromers
Externí odkaz:
https://doaj.org/article/c12a12522d2b48d7ac6e489e58826952
Autor:
Noura S Abul-Husn, Suresh P Annangudi, Avi Ma'ayan, Dinah L Ramos-Ortolaza, Steven D Stockton, Ivone Gomes, Jonathan V Sweedler, Lakshmi A Devi
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25535 (2011)
Opiates produce significant and persistent changes in synaptic transmission; knowledge of the proteins involved in these changes may help to understand the molecular mechanisms underlying opiate dependence. Using an integrated quantitative proteomics
Externí odkaz:
https://doaj.org/article/89107089705243909dd4da0e1e7168a3
Publikováno v:
International journal of health sciences. :1165-1174
Background: Primary goal in modern obstetrics is to deliver a healthy baby in a healthy mother. Birth weight is the most important factor in determining the neonatal outcome and survival.1 So the accurate estimation of fetal weight is one of the impo
Autor:
Krishna, Pendurthi Venkata, V. V., Lakshmi Aparna Devi, Silpa, Gopireddy, Teja, Rahul, Bhupathi, Sirish
Publikováno v:
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2023, Vol. 14 Issue 9, p955-961, 7p