Zobrazeno 1 - 10
of 677
pro vyhledávání: '"Lakshmi A Devi"'
Autor:
Juan C. Sáez, Justin C. Burrell, Catherine M. Cahill, D. Kacy Cullen, Lakshmi A. Devi, Ryan J. Gilbert, Zachary A. Graham, Vadim J. Gurvich, Leif A. Havton, Ravi Iyengar, Rajesh Khanna, Edmund F. Palermo, Mustafa Siddiq, Carlos A. Toro, Walter Vasquez, Wei Zhao, Christopher P. Cardozo
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Over the past decade, boldine, a naturally occurring alkaloid found in several plant species including the Chilean Boldo tree, has garnered attention for its efficacy in rodent models of human disease. Some of the properties that have been attributed
Externí odkaz:
https://doaj.org/article/07edf235e1324a7b9a58860ef7edcbde
Autor:
Mariana Lemos Duarte, Nikita A. Trimbake, Achla Gupta, Christine Tumanut, Xiaomin Fan, Catherine Woods, Akila Ram, Ivone Gomes, Erin N. Bobeck, Deborah Schechtman, Lakshmi A. Devi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Lemos Duarte et al. describe a strategy to produce, validate, and utilize highly-specific recombinant antibodies. As a proof of principle, they demonstrate development and validation of a panel of antibodies against proteins relevant to signaling by
Externí odkaz:
https://doaj.org/article/fa3462494d824628b60f24925ecc50e1
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Anxiety disorders are prevalent across the United States and result in a large personal and societal burden. Currently, numerous therapeutic and pharmaceutical treatment options exist. However, drugs to classical receptor targets have shown limited e
Externí odkaz:
https://doaj.org/article/b50b925463e04c24ac1e7d35123b7843
Publikováno v:
eLife, Vol 10 (2021)
Many signal transduction systems have an apparent redundancy built into them, where multiple physiological agonists activate the same receptors. Whether this is true redundancy, or whether this provides an as-yet unrecognized specificity in downstrea
Externí odkaz:
https://doaj.org/article/3d0d23663e8e4701b7daae6d9fe62f91
Autor:
Douglas L. deAlmeida, Lakshmi A. Devi
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 6, Pp n/a-n/a (2020)
Abstract Cannabidiol (CBD) is the second most abundant component of the Cannabis plant and is known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many studies that examined the behavioral effects of CBD concluded that it lacks the p
Externí odkaz:
https://doaj.org/article/4dea240cf43d481da62d4a1b540ac00a
Autor:
Krishna, Pendurthi Venkata, V. V., Lakshmi Aparna Devi, Silpa, Gopireddy, Teja, Rahul, Bhupathi, Sirish
Publikováno v:
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2023, Vol. 14 Issue 9, p955-961, 7p
Artificial Intelligence(AI), Machine Learning(ML) and Big Data are facilitating the present society as front runner beneficiary, This review highlights the imactful use of AI, ML and Big Data in diverse areas of pharmaceutical fields. Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abed801110448c0aa111db6e679da4d
Publikováno v:
International journal of health sciences. :1165-1174
Background: Primary goal in modern obstetrics is to deliver a healthy baby in a healthy mother. Birth weight is the most important factor in determining the neonatal outcome and survival.1 So the accurate estimation of fetal weight is one of the impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8b56f496d9d3da38b9762f386b1680a
https://doi.org/10.53730/ijhs.v6ns8.11170
https://doi.org/10.53730/ijhs.v6ns8.11170
Autor:
Andreas Zimmer, Nurulain Zaveri, Yung H. Wong, Hiroshi Ueda, John R. Traynor, Lawrence Toll, Eric J. Simon, Toni S. Shippenberg, Stefan Schulz, Philip S. Portoghese, Jean-Claude Meunier, Dominique Massot, Davide Malfacini, Lee-Yuan Liu-Chen, Mary-Jeanne Kreek, Ian Kitchen, Brigitte Kieffer, Eamonn Kelly, Stephen Husbands, Graeme Henderson, Volker Höllt, Christopher Evans, Lakshmi A. Devi, Brian M. Cox, Mark Connor, Olivier Civelli, MacDonald J. Christie, Charles Chavkin, Girolamo Caló, Michael Bruchas, Anna Borsodi
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Opioid and opioid-like receptors are activated by a variety of endogenous peptides including [Met]enkephalin (met), [Leu]enkephalin (leu), β-endorphin (β-end), α-neodynorphin, dynorphin A (dynA), dynorphin B (dynB), big dynorphin (Big dyn), nocice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee9382e24df4bdd47b46cff68280622f
https://doi.org/10.2218/gtopdb/f50/2023.1
https://doi.org/10.2218/gtopdb/f50/2023.1
Autor:
Seshat M. Mack, Ivone Gomes, Amanda K. Fakira, Mariana Lemos Duarte, Achla Gupta, Lloyd Fricker, Lakshmi A. Devi
Publikováno v:
Mol Pharmacol
PEN is an abundant neuropeptide that activates G protein-coupled receptor 83 (GPR83), which is considered a novel therapeutic target due to its roles in regulation of feeding-, reward-, and anxiety-related behaviors. The major form of PEN in the brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11713f966924b896f154eeaf5de5a6b
https://doi.org/10.1124/molpharm.122.000487
https://doi.org/10.1124/molpharm.122.000487