Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lakshmi, Sandhow"'
Autor:
Sean G Rudd, Nikolaos Tsesmetzis, Kumar Sanjiv, Cynthia BJ Paulin, Lakshmi Sandhow, Juliane Kutzner, Ida Hed Myrberg, Sarah S Bunten, Hanna Axelsson, Si Min Zhang, Azita Rasti, Petri Mäkelä, Si'Ana A Coggins, Sijia Tao, Sharda Suman, Rui M Branca, Georgios Mermelekas, Elisée Wiita, Sun Lee, Julian Walfridsson, Raymond F Schinazi, Baek Kim, Janne Lehtiö, Georgios Z Rassidakis, Katja Pokrovskaja Tamm, Ulrika Warpman‐Berglund, Mats Heyman, Dan Grandér, Sören Lehmann, Thomas Lundbäck, Hong Qian, Jan‐Inge Henter, Torsten Schaller, Thomas Helleday, Nikolas Herold
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 3, Pp 1-20 (2020)
Abstract The deoxycytidine analogue cytarabine (ara‐C) remains the backbone treatment of acute myeloid leukaemia (AML) as well as other haematological and lymphoid malignancies, but must be combined with other chemotherapeutics to achieve cure. Yet
Externí odkaz:
https://doaj.org/article/ee94cd1a0d794c99b66c9335300d2f1e
Autor:
Pingnan Xiao, Lakshmi Sandhow, Yaser Heshmati, Makoto Kondo, Thibault Bouderlique, Monika Dolinska, Anne-Sofie Johansson, Mikael Sigvardsson, Marja Ekblom, Julian Walfridsson, Hong Qian
Publikováno v:
Blood Advances, Vol 2, Iss 12, Pp 1480-1494 (2018)
Abstract: Despite increasing evidence for the involvement of bone marrow (BM) hematopoietic stem cell niche in leukemogenesis, how BM mesenchymal stem and progenitor cells (MSPCs) contribute to leukemia niche formation and progression remains unclear
Externí odkaz:
https://doaj.org/article/d16b6fbca23044788d0ecef25d309a60
Autor:
Pingnan Xiao, Monika Dolinska, Lakshmi Sandhow, Makoto Kondo, Anne-Sofie Johansson, Thibault Bouderlique, Ying Zhao, Xidan Li, Marios Dimitriou, George Z. Rassidakis, Eva Hellström-Lindberg, Nagahiro Minato, Julian Walfridsson, David T. Scadden, Mikael Sigvardsson, Hong Qian
Publikováno v:
Blood Advances, Vol 2, Iss 5, Pp 534-548 (2018)
Abstract: Mutations of signal-induced proliferation-associated gene 1 (SIPA1), a RAP1 GTPase-activating protein, were reported in patients with juvenile myelomonocytic leukemia, a childhood myelodysplastic/myeloproliferative neoplasm (MDS/MPN). Sipa1
Externí odkaz:
https://doaj.org/article/9062250244da4e5ca36413d3405d4e8e
Autor:
Monika Dolinska, Huan Cai, Alma Mansson, Jingyi Shen, Pingnan Xiao, Thibault Bouderlique, Xidan Li, Elory Leonard, Marcus Chang, Yuchen Gao, Juan Pablo Medina Giménez, Makoto Kondo, Lakshmi Sandhow, Anne-Sofie Johansson, Stefan Deneberg, Stina Söderlund, Martin Jädersten, Johanna S Ungerstedt, Magnus Tobiasson, Arne Östman, Satu Mustjoki, Leif Stenke, Katarina Le Blanc, Eva S Hellstrom-Lindberg, Sören Lehmann, Marja Ekblom, Ulla Olsson-Strömberg, Mikael Sigvardsson, Hong Qian
Publikováno v:
Blood.
Although tyrosine kinase inhibitors are effective for treating chronic myeloid leukemia (CML), they often fail to eradicate the leukemia-initiating stem cells (LSCs), causing disease persistence and relapse. Evidence indicates that LSC persistence ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ab4930ee1ab1d3b49c957490bdc6c07
https://doi.org/10.1182/blood.2022016896
https://doi.org/10.1182/blood.2022016896
Autor:
Lakshmi Sandhow, Huan Cai, Pingnan Xiao, Elory Leonard, Makoto Kondo, Xiaoyan Sun, Anne-Sofie Johansson, Karl Tryggvason, Maria Kasper, Marcus Järås, Hong Qian
Leukemia cutis or leukemic cell infiltration in skin is one of the common extramedullary manifestations of acute myeloid leukemia (AML) and signifies a poorer prognosis. However, its pathogenesis and maintenance remain understudied. Here, we report m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c6e4eb336f0c0d0ac91d7fe705080c7
https://doi.org/10.1101/2022.05.20.491183
https://doi.org/10.1101/2022.05.20.491183
Autor:
Yoga Yuniadi, Yuyus Kusnadi, Lakshmi Sandhow, Rendra Erika, Dicky A. Hanafy, Caroline Sardjono, R. W. M. Kaligis, Manoefris Kasim, Ganesja M. Harimurti
Publikováno v:
Cardiology Research and Practice, Vol 2016 (2016)
Background. Proangiogenic Hematopoietic Cells (PHC) which comprise diverse mixture of cell types are able to secrete proangiogenic factors and interesting candidate for cell therapy. The aim of this study was to seek for benefit in implantation of PH
Externí odkaz:
https://doaj.org/article/06f6555ab4d04a2d9d78cc52980cc1fa
Autor:
Huan, Cai, Makoto, Kondo, Lakshmi, Sandhow, Pingnan, Xiao, Anne-Sofie, Johansson, Takako, Sasaki, Joanna, Zawacka-Pankau, Karl, Tryggvason, Johanna, Ungerstedt, Julian, Walfridsson, Marja, Ekblom, Hong, Qian
Publikováno v:
Blood. 139(20)
Impairment of normal hematopoiesis and leukemia progression are 2 well-linked processes during leukemia development and are controlled by the bone marrow (BM) niche. Extracellular matrix proteins, including laminin, are important BM niche components.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37f3470d951ca9ef28b82c388f8ef9c2
https://pubmed.ncbi.nlm.nih.gov/34958665
https://pubmed.ncbi.nlm.nih.gov/34958665
Autor:
David T. Scadden, Monika Dolinska, Thibault Bouderlique, Ying Zhao, Pingnan Xiao, Anne-Sofie Johansson, Xidan Li, Hong Qian, Eva Hellström-Lindberg, George Z. Rassidakis, Mikael Sigvardsson, Nagahiro Minato, Marios Dimitriou, Lakshmi Sandhow, Makoto Kondo, Julian Walfridsson
Publikováno v:
Blood Advances. 2:534-548
Mutations of signal-induced proliferation-associated gene 1 ( SIPA1 ), a RAP1 GTPase-activating protein, were reported in patients with juvenile myelomonocytic leukemia, a childhood myelodysplastic/myeloproliferative neoplasm (MDS/MPN). Sipa1 deficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6472fcd78fb00be7cf7d08800c1eb6
https://doi.org/10.1182/bloodadvances.2017013599
https://doi.org/10.1182/bloodadvances.2017013599
Autor:
Hong Qian, Vyacheslav Dyachuk, Lars Sävendahl, Amel Gritli-Linde, Christoph Schweingruber, Andrei S. Chagin, Baoyi Zhou, Maha El Shahawy, Igor Adameyko, Artem V. Artemov, Grigori Enikolopov, Thibault Bouderlique, Xiaoyan Sun, Maria Kasper, Annelie Mollbrink, Joakim Lundeberg, Kaj Fried, Eva Hedlund, E. G. Ivashkin, Lakshmi Sandhow, Meng Xie, Julian Petersen, Maria Hovorakova, Lei Li, Phillip T Newton, Simon Suter
Publikováno v:
Yearbook of Paediatric Endocrinology.
Longitudinal bone growth in children is sustained by growth plates, narrow discs of cartilage that provide a continuous supply of chondrocytes for endochondral ossification1. However, it remains unknown how this supply is maintained throughout childh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1998f1aced1f5b343f6e5e8afc0b1d1
https://doi.org/10.1530/ey.16.5.14
https://doi.org/10.1530/ey.16.5.14
Autor:
Julian Walfridsson, Makoto Kondo, Yaser Heshmati, Pingnan Xiao, Lakshmi Sandhow, Mikael Sigvardsson, Hong Qian, Marja Ekblom, Monika Dolinska, Anne-Sofie Johansson, Thibault Bouderlique
Despite increasing evidence for the involvement of bone marrow (BM) hematopoietic stem cell niche in leukemogenesis, how BM mesenchymal stem and progenitor cells (MSPCs) contribute to leukemia niche formation and progression remains unclear. Using an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2d6903268f8903edad731c7eebcbab
https://europepmc.org/articles/PMC6020803/
https://europepmc.org/articles/PMC6020803/