Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lakmini Kumari Senavirathna"'
Autor:
Lin Liu, Lakmini Kumari Senavirathna, Yurong Liang, Dao Xu, Xuxu Gou, Xiangming Zeng, Roshini Sathiaseelan, Chaoqun Huang, Pengcheng Wang, Xiaoyun Yang
Publikováno v:
Am J Respir Cell Mol Biol
Abnormal activation of lung fibroblasts contributes to the initiation and progression of idiopathic pulmonary fibrosis (IPF). The objective of the present study was to investigate the role of fetal-lethal noncoding developmental regulatory RNA (FENDR
Autor:
Dao Xu, Gayan Bamunuarachchi, Lakmini Kumari Senavirathna, Maria Cristina Munteanu, Quanjin Dang, David W. Kamp, Sankha Hewawasam, Paul Cheresh, Chaoqun Huang, Xiaoyun Yang, Yurong Liang, Kishore Vaddadi, Pulavendran Sivasami, Lin Liu
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8536, p 8536 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8536, p 8536 (2021)
Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive, and usually lethal lung disease and it has been widely accepted that fibroblast proliferation is one of the key characteristics of IPF. Long noncoding RNAs (lncRNAs) play vital roles in t
Publikováno v:
Cells
Cells; Volume 10; Issue 5; Pages: 1005
Cells, Vol 10, Iss 1005, p 1005 (2021)
Cells; Volume 10; Issue 5; Pages: 1005
Cells, Vol 10, Iss 1005, p 1005 (2021)
Glyceraldehyde-derived advanced glycation end products (AGEs) play an important role in the pathogenesis of many diseases including cancer. Accumulation of intracellular AGEs could stimulate cancer induction and facilitate cancer progression. We eval
Autor:
Lakmini Kumari Senavirathna, Hiroyuki Yamaguchi, Matthew D. Meyer, Sheng Pan, Li He, Yoshihiro Komatsu
Publikováno v:
Development
Intramembranous ossification, which consists of direct conversion of mesenchymal cells to osteoblasts, is a characteristic process in skull development. One critical role of these osteoblasts is to secrete collagen-containing bone matrix. However, it
Publikováno v:
Physiological Reports, Vol 8, Iss 1, Pp n/a-n/a (2020)
Physiological Reports
Physiological Reports
One of the key characteristics of idiopathic pulmonary fibrosis (IPF) is accumulation of excess fibrous tissue in the lung, which leads to hypoxic conditions. Transforming growth factor (TGF) β is a major mediator that promotes the differentiation o
Autor:
Gayan Premaratne, Sadagopan Krishnan, Lakmini Kumari Senavirathna, Zainab H. Al Mubarak, Lin Liu
Publikováno v:
Sensors and Actuators B: Chemical. 253:368-375
Circulating serum nucleotide biomarkers are useful indicators for early diagnosis of cancer, respiratory illnesses, and other deadly diseases. In this work, we compared detection performances of a quartz crystal microbalance (QCM), which is a mass se
Publikováno v:
The FASEB Journal. 32
Autor:
Ruchika Fernando, Ashish Ranjan, Lakmini Kumari Senavirathna, E. R. Benton, Jerimy C. Polf, Y. Zheng, Daqing Piao, Danny Maples, Kenneth E. Bartels
Publikováno v:
Pharmaceutical Research. 31:3120-3126
The objectives of this study were to: 1) determine if mild hyperthermia (40–42°C) can sensitize tumor cells for more effective proton beam radiotherapy (PBRT); 2) characterize the survival fraction of cells exposed to PBRT; and 3) characterize rel
Autor:
Lin Liu, Lakmini Kumari Senavirathna, Yurong Liang, Dao Xu, Gayan Bamunuarachchi, Chunling Zhao, Xiaoyun Yang, Chaoqun Huang, Zhengyu Zhu, Lan Xu, Yang Wang, Kong Lin
Publikováno v:
Cellular Microbiology
Due to an increasing emergence of new and drug‐resistant strains of the influenza A virus (IAV), developing novel measures to combat influenza is necessary. We have previously shown that inhibiting Wnt/β‐catenin pathway reduces IAV infection. In
Autor:
Ashish Ranjan, Ruchika Fernando, Lakmini Kumari Senavirathna, Danny Maples, Jerimy C. Polf, Y Zheng
Publikováno v:
Theranostics
Multicellular Tumor Spheroids (MCTS) strongly resemble tumor tissues, which makes them useful tools for radiation biology studies and screening of various chemotherapeutics. The goal of this pilot study was to use MCTS as an in vitro model to determi