Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lakhvir K. Assi"'
Autor:
Lakhvir K Assi, Natasha McIntyre, Simon Fraser, Scott Harris, Colin A Hutchison, Chris W McIntyre, Paul Cockwell, Maarten W Taal
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0129980 (2015)
A major component of increased mortality risk in people with chronic kidney disease (CKD) is associated with non-traditional cardiovascular risk factors including markers of inflammation. We studied whether a novel marker of systemic inflammation, el
Externí odkaz:
https://doaj.org/article/8c57ca8f454a4b0c89a4fa21a9d53c2a
Autor:
Lakhvir K Assi, Natasha McIntyre, Simon Fraser, Scott Harris, Colin A Hutchison, Chris W McIntyre, Paul Cockwell, Maarten W Taal
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141404 (2015)
Externí odkaz:
https://doaj.org/article/c555b0ae15bd4231a184c325e7ff1013
Autor:
Paul Cockwell, Philip A. Kalra, Richard Hoefield, Anne Burmeister, Lakhvir K. Assi, James Ritchie
Publikováno v:
Clinical Journal of the American Society of Nephrology. 10:740-749
High levels of serum polyclonal combined Ig free light chains are associated with inflammation and decreased excretory kidney function, and they are an independent risk factor for mortality. Whether combined Ig free light chain predicted mortality an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9d4ae9502b2197f7eefd260ee10fda
https://doi.org/10.2215/cjn.09660914
https://doi.org/10.2215/cjn.09660914
Autor:
A. H. Barnett, Srikanth Bellary, Lakhvir K. Assi, Guy Pratt, Charles J. Ferro, Paul Cockwell, Colin A. Hutchison, Richard G. Hughes, A. Burmeister
Publikováno v:
International Journal of Laboratory Hematology. 36:415-424
Introduction: Serum concentrations of polyclonal free light chains (FLC) represent the activity of the adaptive immune system. This study assessed the relationship between polyclonal FLC and the established marker of innate immunity, C-reactive prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09adb2c2310947fb340a8ade85ff51d1
https://doi.org/10.1111/ijlh.12159
https://doi.org/10.1111/ijlh.12159
Autor:
Rachel E. Hayden, Christopher M. Bunce, Lakhvir K Assi, Hema Chahal, Farhat L. Khanim, Janet M. Lord, Peter Hampson, Anneke Mulder
Publikováno v:
Blood. 106:1362-1368
Ingenol 3-angelate (PEP005) is a selective small molecule activator of protein kinase C (PKC) extracted from the plant Euphorbia peplus, whose sap has been used as a traditional medicine for the treatment of skin conditions including warts and cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891fde3a0c7600e7652878d1eb9a018a
https://doi.org/10.1182/blood-2004-10-4117
https://doi.org/10.1182/blood-2004-10-4117
Autor:
Mike Salmon, Helen M. McGettrick, Keqing Wang, Dagmar Scheel-Toellner, Paul Webb, Erich Gulbins, Louise E. Clough, Neal Parkes, Rachel Craddock, Janet M. Lord, Lakhvir K Assi
Publikováno v:
Blood. 104:2557-2564
Neutrophils are abundant, short-lived leukocytes, and their death by apoptosis is central to hemostasis and the resolution of inflammation, yet the trigger for their entry into apoptosis is unknown. We show here that death receptor signaling, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b229d10dfc612e7e6e57e7c54365ed63
https://doi.org/10.1182/blood-2004-01-0191
https://doi.org/10.1182/blood-2004-01-0191
Autor:
Rachel Craddock, See Heng Wong, Mike Salmon, Janet M. Lord, Lakhvir K Assi, Keqing Wang, Dagmar Scheel-Toellner, Paul Webb
Publikováno v:
Biochemical Society Transactions. 32:461-464
Neutrophils are very abundant, short-lived leucocytes and their death by apoptosis is central to homoeostasis and the resolution of inflammation, yet the trigger for apoptosis is still a topic of debate. Depolarization of the mitochondrial membrane h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e6d318413e328a98938a2ab73a7293
https://doi.org/10.1042/bst0320461
https://doi.org/10.1042/bst0320461
Autor:
Neil T. Raymond, Stephen Harding, Jeffrey Faint, Srikanth Bellary, Lakhvir K. Assi, Colin A. Hutchison, Anthony H. Barnett
Publikováno v:
Diabetes care. 37(7)
OBJECTIVE Elevated polyclonal serum immunoglobulin free light chains (FLCs; combined FLCκ+FLCλ [cFLC]) are associated with adverse clinical outcomes and increased mortality; we investigated cFLC and cardiovascular disease (CVD) events in type 2 dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6da115666b54ee8a129462561868b4
https://pubmed.ncbi.nlm.nih.gov/24742658
https://pubmed.ncbi.nlm.nih.gov/24742658
Autor:
Colette E. Jackson, Stephen Harding, Lakhvir K. Assi, Jeffrey Faint, Bridget Gunson, Supratik Basu, Adeel Mushtaq, David Sutton, Paul Cockwell, Hugh D. Carr-Smith, Paul J. Showell, Philip A. Kalra
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM).
Background: Elevated polyclonal serum free light chain (FLC) levels have been associated with increased mortality and disease activity in many conditions. Currently, polyclonal FLC quantification requires summation of individual FLCκ and FLCλ assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209afafb02b2e78eac212275df61ae79
https://doi.org/10.1515/cclm-2014-0279
https://doi.org/10.1515/cclm-2014-0279
Autor:
Paul Webb, Lakhvir K Assi, Keqing Wang, Janet M. Lord, Mike Salmon, Dagmar Scheel-Toellner, Rachel Craddock
Publikováno v:
Biochemical Society Transactions. 32:679-681
Neutrophils die by apoptosis spontaneously within 12–24 h of their release from the bone marrow. The mechanism regulating entry of neutrophils into apoptosis at the end of their life-span is currently under debate. Our data suggest that neutrophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3322e1164bf814c87af662c503d523fd
https://doi.org/10.1042/bst0320679
https://doi.org/10.1042/bst0320679