Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lakhmir, Chawla"'
Autor:
Anjali Chakradhar, Rebecca M. Baron, Mayra Pinilla Vera, Prasad Devarajan, Lakhmir Chawla, Peter C. Hou
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Sepsis-associated acute respiratory distress syndrome (ARDS) is a life-threatening condition in critical care medicine for which there is a substantial need for early prognostic biomarkers of outcome. The present study seeks to link plasma r
Externí odkaz:
https://doaj.org/article/5859a574469a4b28913a527ca8e96063
Autor:
Stuart L. Goldstein, Kelli A. Krallman, Jean-Philippe Roy, Michaela Collins, Ranjit S. Chima, Rajit K. Basu, Lakhmir Chawla, Lin Fei
Publikováno v:
Kidney International Reports, Vol 8, Iss 12, Pp 2690-2700 (2023)
Introduction: Critically ill admitted patients are at high risk of acute kidney injury (AKI). The renal angina index (RAI) and urinary biomarker neutrophil gelatinase-associated lipocalin (uNGAL) can aid in AKI risk assessment. We implemented the Tri
Externí odkaz:
https://doaj.org/article/9553324e22d9404dbe8e021625da5590
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-15 (2023)
Abstract Sepsis and septic shock remain drivers for morbidity and mortality in critical illness. The clinical picture of patients presenting with these syndromes evolves rapidly and may be characterised by: (a) microbial host invasion, (b) establishm
Externí odkaz:
https://doaj.org/article/1d4ed2d050d44a40a4addd2bc6d3f1df
Publikováno v:
Critical Care, Vol 25, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/7fbde3e1be2244cbbc64f09f1ad0a3e3
Autor:
Stuart L. Goldstein, Kelli A. Krallman, Cassie Kirby, Jean-Philippe Roy, Michaela Collins, Kaylee Fox, Alexandra Schmerge, Sarah Wilder, Bradley Gerhardt, Ranjit Chima, Rajit K. Basu, Lakhmir Chawla, Lin Fei
Publikováno v:
Kidney International Reports. 7:1842-1849
Acute kidney injury (AKI) occurs in one-fourth of children and young adults admitted to pediatric intensive care unit (PICU). Severe AKI (sAKI; Kidney Disease: Improving Global Outcomes stage 2 or 3) is associated with morbidity and mortality. An AKI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb2151470ed6c624ac50d6a94b40749
https://doi.org/10.1016/j.ekir.2022.05.021
https://doi.org/10.1016/j.ekir.2022.05.021
Autor:
Melanie Meersch, Raphael Weiss, Christina Massoth, Mira Küllmar, Khaschayar Saadat-Gilani, Manuel Busen, Lakhmir Chawla, Giovanni Landoni, Rinaldo Bellomo, Joachim Gerss, Alexander Zarbock
Background: Hyperreninemia after cardiac surgery is associated with cardiovascular instability. Angiotensin II (AT-II) could potentially attenuate hyperreninemia while maintaining target blood pressure. This study assesses the association between AT-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be69692d4bd61bf0300db8f1ab2d8b5
Autor:
Bellomo, Rinaldo, Wunderink, Richard, Szerlip, Harold, English, Shane, Busse, Laurence, Deane, Adam, Khanna, Ashish, McCurdy, Michael, Ostermann, Marlies, Young, Paul, Handisides, Damian, Lakhmir Chawla, Tidmarsh, George, Albertson, Timothy
Additional file 1: Figure S1. Angiotensin I distribution at baseline. Figure S2. Angiotensin II distribution at baseline. Figure S3. Angiotensin I/II ratio distribution at baseline.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06016d9c157405fd7d4ab5f9b4983400
Autor:
Jonathan DeAntonio, Geoffrey Ledoux, Azra Bihorac, Gyorgy Frendl, Shane English, Constantine Karvellas, Adam Deane, Andrew Bersten, Luigi Camporota, ANAHITA ROUZE, Raghavan Murugan, Erika Wilkman, Shailesh Bihari, Brent Richards, Paul Young, Lakhmir Chawla, Sebastien Preau, Robert Duncan Hite, Marlies Ostermann, John Prowle, Tony Whitehouse
Publikováno v:
Critical care medicine, 46(6), 949-957. Lippincott Williams and Wilkins
Critical Care Medicine
Critical Care Medicine
Supplemental Digital Content is available in the text.
Objective: Acute kidney injury requiring renal replacement therapy in severe vasodilatory shock is associated with an unfavorable prognosis. Angiotensin II treatment may help these patients
Objective: Acute kidney injury requiring renal replacement therapy in severe vasodilatory shock is associated with an unfavorable prognosis. Angiotensin II treatment may help these patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b302fab72f4f41d6fa563698e8f91f2b
https://doi.org/10.1097/ccm.0000000000003092
https://doi.org/10.1097/ccm.0000000000003092
Autor:
Erik Kulstad, David Brealey, Zia Sadique, Sharon Micallef, John Myburgh, Timothy Coats, Mervyn Singer, Alexander T. Limkakeng, Erika Wilkman, Julian Bion, Dorrilyn Rajbhandari, Anthony Delaney, Michael Bailey, Alisa Higgins, Alistair Nichol, Lakhmir Chawla, David Huang, John Kellum, Wesley Self, Daniel Harvey, Kathryn Rowan, Ednan Bajwa, David Harrison, Paul Mouncey, Richard Grieve, Michael Reade
Publikováno v:
New England Journal of Medicine. 376:2223-2234
BACKGROUND: After a single-center trial and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality from septic shock, three multicenter trials (ProCESS, ARISE, and ProMISe) showed no benefit. This meta-analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb140de1ed3661b71284bd1bcda8640b
https://doi.org/10.1056/nejmoa1701380
https://doi.org/10.1056/nejmoa1701380
Autor:
Kealy Ham, Boldt, David, McCurdy, Michael, Busse, Laurence, Favory, Raphael, Gong, Michelle, Khanna, Ashish, Chock, Stefan, Zeng, Feng, Lakhmir Chawla, Tidmarsh, George, Ostermann, Marlies
Additional file 1: Table S1. Summary of Treatment-Emergent Adverse Events (regardless of causality) Reported in >5% of Patients in Either Dosing Subgroup.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27183f0f5b1eb4f0d0e8c62f74db65db