Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Lake N, Paul"'
Autor:
Yetunde A. Ayinuola, Sheiny Tjia-Fleck, Bradley M. Readnour, Zhong Liang, Olawole Ayinuola, Lake N. Paul, Shaun W. Lee, Vincent A. Fischetti, Victoria A. Ploplis, Francis J. Castellino
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The proteolytic activity of human plasmin (hPm) is utilized by various cells to provide a surface protease that increases the potential of cells to migrate and disseminate. Skin-trophic Pattern D strains of Streptococcus pyogenes (GAS), e.g., GAS iso
Externí odkaz:
https://doaj.org/article/4262c9215512430a994f4458ce0b40ed
Autor:
Chun-Liang Chen, Lake N. Paul, James C. Mermoud, Calvin Nicklaus Steussy, Cynthia V. Stauffacher
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Mevalonate diphosphate decarboxylase (MDD) is a key enzyme in the mevalonate pathway and catalyses the decarboxylation of mevalonate-5-diphosphate to isopentenyl diphosphate. Here, the authors provide insights into the conformational changes that occ
Externí odkaz:
https://doaj.org/article/b0d17fe2854d4bb9a893293053f08b6e
AAV analysis by sedimentation velocity analytical ultracentrifugation: beyond empty and full capsids
Autor:
Alexander E. Yarawsky, Valeria Zai-Rose, Hazel M. Cunningham, John W. Burgner, Michael T. DeLion, Lake N. Paul
Publikováno v:
European Biophysics Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72e5f30c2ffa8eb418f6a5884fb8ad20
https://doi.org/10.1007/s00249-023-01646-z
https://doi.org/10.1007/s00249-023-01646-z
Autor:
Yen-Hsing Li, Jia Luo, Yung-Yi C. Mosley, Victoria E. Hedrick, Lake N. Paul, Julia Chang, GuangJun Zhang, Yu-Kuo Wang, Max R. Banko, Anne Brunet, Shihuan Kuang, Jen-Leih Wu, Chun-Ju Chang, Matthew P. Scott, Jer-Yen Yang
Publikováno v:
Cell Reports, Vol 12, Iss 4, Pp 599-609 (2015)
The Hedgehog (Hh) pathway regulates cell differentiation and proliferation during development by controlling the Gli transcription factors. Cell fate decisions and progression toward organ and tissue maturity must be coordinated, and how an energy se
Externí odkaz:
https://doaj.org/article/6c6e2d5b43f840b389736734999fd417
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Mevalonate diphosphate decarboxylases (MDDs) catalyze the ATP-dependent-Mg2+-decarboxylation of mevalonate-5-diphosphate (MVAPP) to produce isopentenyl diphosphate (IPP), which is essential in both eukaryotes and prokaryotes for polyisoprenoid synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08199288d5a16cbd79d061e056d1ef9
http://link.springer.com/article/10.1038/s41467-020-17733-0
http://link.springer.com/article/10.1038/s41467-020-17733-0
Autor:
Theresa D'Aquila, Devika Sirohi, Jeffrey M Grabowski, Victoria E Hedrick, Lake N Paul, Andrew S Greenberg, Richard J Kuhn, Kimberly K Buhman
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126823 (2015)
Dietary fat absorption by the small intestine is a multistep process that regulates the uptake and delivery of essential nutrients and energy. One step of this process is the temporary storage of dietary fat in cytoplasmic lipid droplets (CLDs). The
Externí odkaz:
https://doaj.org/article/7f4dc2e9a9ad431c81db4d24bf3426d6
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30102 (2012)
Expression of KdpFABC, a K(+) pump that restores osmotic balance, is controlled by binding of the response regulator KdpE to a specific DNA sequence (kdpFABC(BS)) via the winged helix-turn-helix type DNA binding domain (KdpE(DBD)). Exploration of E.
Externí odkaz:
https://doaj.org/article/1ef3627edec140e3ba2bf0a425284784
Publikováno v:
Journal of Biological Chemistry. 292:21340-21351
The mevalonate pathway produces isopentenyl diphosphate (IPP), a building block for polyisoprenoid synthesis, and is a crucial pathway for growth of the human bacterial pathogen Enterococcus faecalis. The final enzyme in this pathway, mevalonate diph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44181970686aa93af881d6008057197
https://doi.org/10.1074/jbc.m117.802223
https://doi.org/10.1074/jbc.m117.802223
Autor:
Tony R. Hazbun, Jean-Christophe Rochet, Lake N. Paul, Holli M. Drendel, Kiran Aslam, Kourtney M. Goode, Chai-jui Tsai, Josephat M. Asiago
Publikováno v:
Department of Medicinal Chemistry and Molecular Pharmacology Faculty Publications
The Saccharomyces cerevisiae heat shock protein Hsp31 is a stress-inducible homodimeric protein that is involved in diauxic shift reprogramming and has glyoxalase activity. We show that substoichiometric concentrations of Hsp31 can abrogate aggregati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b378e5311ce0a0383b1d5d0dbd36e60
https://doi.org/10.1074/jbc.m115.678367
https://doi.org/10.1074/jbc.m115.678367
Publikováno v:
Current Protocols in Chemical Biology
Proteomic studies rely heavily on the use of liquid chromatography (LC)-mass spectrometry (MS and MS/MS) analyses to provide information about protein composition and function. Profiling the proteome can be the first step to understanding biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7257e66ff87194d9dcfc68108b187b45
https://doi.org/10.1002/9780470559277.ch140272
https://doi.org/10.1002/9780470559277.ch140272