Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Laith, Alexander"'
Publikováno v:
BJPsych Open, Vol 10, Pp S122-S123 (2024)
Aims To replace pre-existing paper-based and informal handover systems with a confidential electronic handover system for on-call doctors across a large South London mental health trust, thereby improving the safety and quality of handovers. Methods
Externí odkaz:
https://doaj.org/article/d2977fddbda64fb5ab1492f45bef234d
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Activity changes within the anterior cingulate cortex (ACC) are implicated in the antidepressant effects of ketamine, but the ACC is cytoarchitectonically and functionally heterogeneous and ketamine’s effects may be subregion specific. In
Externí odkaz:
https://doaj.org/article/02b4f30b2c2345608942b4bf7b9ba630
Autor:
Matthew H. V. Byrne, James Ashcroft, Laith Alexander, Jonathan C. M. Wan, Anmol Arora, Megan E. L. Brown, Anna Harvey, Andrew Clelland, Nicholas Schindler, Cecilia Brassett, Rachel Allan, on behalf of the MedEd Collaborative
Publikováno v:
BMC Medical Education, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background The coronavirus disease 2019 pandemic has led to global disruption of healthcare. Many students volunteered to provide clinical support. Volunteering to work in a clinical capacity was a unique medical education opportunity; howev
Externí odkaz:
https://doaj.org/article/8288a43103bc48a289e023fab9c56afd
Autor:
Laith Alexander, Christian M. Wood, Philip L. R. Gaskin, Stephen J. Sawiak, Tim D. Fryer, Young T. Hong, Lauren McIver, Hannah F. Clarke, Angela C. Roberts
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Alexander et al. causally implicate over-activity in primate subgenual cingulate in affective and cardiovascular dysfunction relevant to anxiety and depression. Over-activation led to elevated activity in a stress-related network whilst decreasing ac
Externí odkaz:
https://doaj.org/article/c4882c5246f44a9f9ba8c63aa0cd943b
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100454- (2021)
Summary: Blunted reward responsivity is associated with anhedonia in humans and is a core feature of depression. This protocol describes how to train the common marmoset, Callithrix jacchus, on an appetitive Pavlovian conditioning paradigm to measure
Externí odkaz:
https://doaj.org/article/4c34f392d3784dfa8d273d7ec436b6c0
Publikováno v:
MedEdPublish, Vol 9, Iss 1 (2020)
During the COVID-19 pandemic, early graduation of senior medical students simultaneously offers useful clinical experience in preparation for junior doctor posts, whilst helping address staffing shortages due to illness or self-isolation. Having rece
Externí odkaz:
https://doaj.org/article/3b58fcf2fa4c4a7391ff05b02f2856b5
Autor:
Allan Young, Laith Alexander
Publikováno v:
BJPsych Advances. 29:117-130
SUMMARYThis review highlights some of the recent advances in the psychopharmacology of major depressive disorder (MDD). We synthesise evidence on emerging pharmacological therapies targeting the serotonergic system, before exploring several novel tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d922390a56eb3c640519498531df3d5c
https://doi.org/10.1192/bja.2022.14
https://doi.org/10.1192/bja.2022.14
Autor:
Christian M. Wood, Laith Alexander, Johan Alsiö, Andrea M. Santangelo, Lauren McIver, Gemma J. Cockcroft, Angela C. Roberts
Publikováno v:
Science Translational Medicine. 15
Poor outcomes are common in individuals with anxiety and depression, and the brain circuits underlying symptoms and treatment responses remain elusive. To elucidate these neural circuits, experimental studies must specifically manipulate them, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5efa42ad7815a7c6359f4efc7da3ede
https://doi.org/10.1126/scitranslmed.ade1779
https://doi.org/10.1126/scitranslmed.ade1779
Autor:
Megan E. L. Brown, Matthew H V Byrne, Jonathan C M Wan, Cecilia Brassett, Laith Alexander, James Ashcroft, Nicholas Schindler, Anna Harvey
Publikováno v:
Postgraduate Medical Journal.
Purpose Understanding the factors that influence prosocial behaviour during the COVID-19 pandemic is essential due to the disruption to healthcare provision. Methods We conducted an in-depth, mixed-methods cross-sectional survey, from 2 May 2020 to 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953a176f7a3d44f360c18778e7e3161b
https://doi.org/10.1093/postmj/qgad015
https://doi.org/10.1093/postmj/qgad015
Autor:
Hannah Hartland, Kimia Mahdavi, Luke A Jelen, Rebecca Strawbridge, Allan H Young, Laith Alexander
BackgroundSubanaesthetic doses of ketamine may be effective in treating symptoms of anxiety, but the time profile of ketamine’s anxiolytic effect is ill-defined. This systematic review and meta-analysis of randomised controlled trials investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4bd13dce692c006c7c1d15d469c537
https://doi.org/10.1101/2022.12.09.22283264
https://doi.org/10.1101/2022.12.09.22283264
