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pro vyhledávání: '"Laitala, A. (Anu)"'
Autor:
Laitala, A. (Anu)
Erythropoiesis is the process of red blood cell production. The main regulator is the erythropoietin (EPO) hormone, which is strongly upregulated in low oxygen concentration (hypoxia) in cells via the hypoxia-inducible transcription factor HIF. The s
Externí odkaz:
http://urn.fi/urn:isbn:9789526206943
Autor:
Tapio, J. (Joona), Halmetoja, R. (Riikka), Dimova, E. Y. (Elitsa Y.), Mäki, J. M. (Joni M.), Laitala, A. (Anu), Walkinshaw, G. (Gail), Myllyharju, J. (Johanna), Serpi, R. (Raisa), Koivunen, P. (Peppi)
Hypoxia-inducible factor (HIF) prolyl 4-hydroxylases (HIF-P4Hs 1–3) are druggable targets in renal anemia, where pan-HIF-P4H inhibitors induce an erythropoietic response. Preclinical data suggest that HIF-P4Hs could also be therapeutic targets for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::f54e4f84e4306e763f2df0c51602a8d9
http://urn.fi/urn:nbn:fi-fe2023022228288
http://urn.fi/urn:nbn:fi-fe2023022228288