Synergistic antifungal interaction of N-(butylcarbamothioyl) benzamide and amphotericin B against Cryptococcus neoformans

Autor: Gabriella Maria Andriani, Lais Fernanda de Almeida Spoladori, Marciéli Fabris, Priscila Goes Camargo, Patrícia Morais Lopes Pereira, Jussevania Pereira Santos, Guilherme Bartolomeu-Gonçalves, Lais Alonso, Cesar Armando Contreras Lancheros, Antonio Alonso, Celso Vataru Nakamura, Fernando Macedo, Phileno Pinge-Filho, Lucy Megumi Yamauchi, Marcelle de Lima Ferreira Bispo, Eliandro Reis Tavares, Sueli Fumie Yamada-Ogatta

Publikováno v: Frontiers in Microbiology, Vol 14 (2023)

IntroductionCryptococcus neoformans is one of the leading causes of invasive fungal infections worldwide. Cryptococcal meningoencephalitis is the main challenge of antifungal therapy due to high morbidity and mortality rates, especially in low- and m

Externí odkaz: https://doaj.org/article/fa9ac02878f4489fae440abbd9a51c20

Analysis of the Interactions of Amphotericin B with the Leishmania Plasma Membrane Using EPR Spectroscopy

Autor: Sebastião Antonio Mendanha, Antonio Alonso, Miriam Leandro Dorta, Lais Alonso

Publikováno v: The Journal of Physical Chemistry B. 124:10157-10165

Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to study the interactions of amphotericin B (AmB) with the plasma membrane of Leishmania amazonensis promastigotes, erythr...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79e76dcc2ee4a1425e9048b28a40f1b0
https://doi.org/10.1021/acs.jpcb.0c07721

Ivermectin and curcumin cause plasma membrane rigidity in Leishmania amazonensis due to oxidative stress

Autor: Lais, Alonso, Miriam Leandro, Dorta, Antonio, Alonso

Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1864:183977

Spin label electron paramagnetic resonance (EPR) spectroscopy was used to study the mechanisms of action of ivermectin and curcumin against Leishmania (L.) amazonensis promastigotes. EPR spectra showed that treatment of the parasites with both compou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ff5346e0c8be5dbb871b2a7dd1b47b
https://doi.org/10.1016/j.bbamem.2022.183977

Analysis of the Interactions of Amphotericin B with the

Autor: Lais, Alonso, Sebastião Antônio, Mendanha, Miriam Leandro, Dorta, Antonio, Alonso

Publikováno v: The journal of physical chemistry. B. 124(45)

Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to study the interactions of amphotericin B (AmB) with the plasma membrane of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0aead20b81e3dcffbe3a6560624b3220
https://pubmed.ncbi.nlm.nih.gov/33119317

Synthesis, Antileishmanial Activity and Spin Labeling EPR Studies of Novel β-Carboline-Oxazoline and β-Carboline-Dihydrooxazine Derivatives

Autor: Willian Ferreira da Costa, Paula Baréa, Maria Helena Sarragiotto, Lais Alonso, Celso Vataru Nakamura, Aline R. de Oliveira, Jéssica Carreira de Paula, Antonio Alonso

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 31, Issue: 6, Pages: 1170-1185, Published: 08 JUN 2020
Journal of the Brazilian Chemical Society v.31 n.6 2020
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

A series of novel 1-(substituted-phenyl)-3-(4,5-dihydro-1,3-oxazol-2-yl)-9H-β-carboline (8a-8i) and 1-(substituted-phenyl)-3-(5,6-dihydro-4H-1,3-oxazin-2-yl)-9H-β-carboline (9a-9h) derivatives, as well as their respective N-(chloroalkyl)-1-(substit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a4f17f05ca796b86747b3fe981efe8
https://doi.org/10.21577/0103-5053.20200003