Zobrazeno 1 - 10
of 1 472
pro vyhledávání: '"Lairson A"'
Autor:
Yijiong Yang, Stacy A. Drake, Jing Wang, Gordon C. Shen, Hongyu Miao, Robert O. Morgan, Xianglin L. Du, David R. Lairson
Publikováno v:
Aging Medicine, Vol 7, Iss 1, Pp 52-59 (2024)
Abstract Introduction Addressing femoral neck fractures resulting from ground‐level falls in older adults with Alzheimer's disease (AD) involves a personalized treatment plan. There is considerable ongoing debate concerning the relative advantages
Externí odkaz:
https://doaj.org/article/c782beb3a186422e86c05b1c44ae58f8
Autor:
Bertin, Paul, Rector-Brooks, Jarrid, Sharma, Deepak, Gaudelet, Thomas, Anighoro, Andrew, Gross, Torsten, Martinez-Pena, Francisco, Tang, Eileen L., S, Suraj M, Regep, Cristian, Hayter, Jeremy, Korablyov, Maksym, Valiante, Nicholas, van der Sloot, Almer, Tyers, Mike, Roberts, Charles, Bronstein, Michael M., Lairson, Luke L., Taylor-King, Jake P., Bengio, Yoshua
For large libraries of small molecules, exhaustive combinatorial chemical screens become infeasible to perform when considering a range of disease models, assay conditions, and dose ranges. Deep learning models have achieved state of the art results
Externí odkaz:
http://arxiv.org/abs/2202.04202
Autor:
Shim, Hong Seok, Iaconelli, Jonathan, Shang, Xiaoying, Li, Jiexi, Lan, Zheng D., Jiang, Shan, Nutsch, Kayla, Beyer, Brittney A., Lairson, Luke L., Boutin, Adam T., Bollong, Michael J., Schultz, Peter G., DePinho, Ronald A.
Publikováno v:
In Cell 25 July 2024 187(15):4030-4042
Autor:
Miao, Hongyu, Gao, Qianmiao, Feng, Han, Zhong, Chengxue, Zhu, Pengwei, Wu, Liang, Swartz, Michael D., Luo, Xi, DeSantis, Stacia M., Lai, Dejian, Bauer, Cici, Pérez, Adriana, Rong, Libin, Lairson, David
The sudden onset of the coronavirus (SARS-CoV-2) pandemic has resulted in tremendous loss of human life and economy in more than 210 countries and territories around the world. While self-protections such as wearing mask, sheltering in place and quar
Externí odkaz:
http://arxiv.org/abs/2006.06416
Akademický článek
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Akademický článek
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Autor:
Claire Lee, Jinny, Shirey, Ryan J., Turner, Lewis D., Park, Hyeri, Lairson, Luke L., Janda, Kim D.
Publikováno v:
In Results in Chemistry January 2024 7
Autor:
Kuburich, Nick A., den Hollander, Petra, Castaneda, Maria, Pietilä, Mika, Tang, Ximing, Batra, Harsh, Martínez-Peña, Francisco, Visal, Tanvi H., Zhou, Tieling, Demestichas, Breanna R., Dontula, Ritesh V., Liu, Jojo Y., Maddela, Joanna Joyce, Padmanabhan, Reethi S., Phi, Lan Thi Hanh, Rosolen, Matthew J., Sabapathy, Thiru, Kumar, Dhiraj, Giancotti, Filippo G., Lairson, Luke L., Raso, Maria Gabriela, Soundararajan, Rama, Mani, Sendurai A.
Publikováno v:
In Cell Reports 26 December 2023 42(12)
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101349- (2024)
Phospholipase D3 (PLD3) and D4 (PLD4) are endolysosomal exonucleases of ssDNA and ssRNA that regulate innate immunity. Polymorphisms of these enzymes are correlated with numerous human diseases, including Alzheimer’s, rheumatoid arthritis, and syst
Externí odkaz:
https://doaj.org/article/cc3b7d81355b40c5bcdbda876efff1c1
Autor:
Nick A. Kuburich, Petra den Hollander, Maria Castaneda, Mika Pietilä, Ximing Tang, Harsh Batra, Francisco Martínez-Peña, Tanvi H. Visal, Tieling Zhou, Breanna R. Demestichas, Ritesh V. Dontula, Jojo Y. Liu, Joanna Joyce Maddela, Reethi S. Padmanabhan, Lan Thi Hanh Phi, Matthew J. Rosolen, Thiru Sabapathy, Dhiraj Kumar, Filippo G. Giancotti, Luke L. Lairson, Maria Gabriela Raso, Rama Soundararajan, Sendurai A. Mani
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113470- (2023)
Summary: Epithelial-mesenchymal transition (EMT) empowers epithelial cells with mesenchymal and stem-like attributes, facilitating metastasis, a leading cause of cancer-related mortality. Hybrid epithelial-mesenchymal (E/M) cells, retaining both epit
Externí odkaz:
https://doaj.org/article/253d5b2d577048579918e7d5d14d75ec