Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laird C. Sheldahl"'
Autor:
Michael R. Hayden, Y. Paul Goldberg, A. Hoskin-Mott, Laird C. Sheldahl, Michael T. Trese, Marcia L.E. MacDonald, Marie-Pierre Dubé, Randall T. Moon, Simon N. Pimstone, Mark E. Samuels, J Zeisler, Lin-Hua Zhang, B. Zheng, Ajamete Kaykas, Barkur S. Shastry, Lee Siebert, Duane L. Guernsey, Johane M Robitaille, Roshni R. Singaraja
Publikováno v:
Nature Genetics. 32:326-330
Familial exudative vitreoretinopathy (FEVR) is a hereditary ocular disorder characterized by a failure of peripheral retinal vascularization. Loci associated with FEVR map to 11q13-q23 (EVR1; OMIM 133780, ref. 1), Xp11.4 (EVR2; OMIM 305390, ref. 2) a
Autor:
Benjamin N.R. Cheyette, Randall T. Moon, Ken-Ichi Takemaru, Jeffrey R. Miller, Laird C. Sheldahl, Natasha Khlebtsova, Eric P. Fox, Thomas Earnest, Joshua S. Waxman
Publikováno v:
Developmental Cell. 2(4):449-461
Dapper was isolated in a screen for proteins interacting with Dishevelled, a key factor in Wnt signaling. Dapper and Dishevelled colocalize intracellularly and form a complex with Axin, GSK-3, CKI, and beta-catenin. Overexpression of Dapper increases
Publikováno v:
Developmental Biology. 241:229-237
The Wnt/beta-catenin signaling pathway plays multiple roles during embryonic development, only a few of which have been extensively characterized. Although domains of Wnt expression have been identified throughout embryogenesis, anatomical and molecu
Publikováno v:
Mechanisms of Development. 106:61-76
Convergent extension movements are the main driving force of Xenopus gastrulation. A fine-tuned regulation of cadherin-mediated cell-cell adhesion is thought to be required for this process. Members of the Wnt family of extracellular glycoproteins ha
Publikováno v:
Trends in Genetics. 16:279-283
Members of the vertebrate Wnt family have been subdivided into two functional classes according to their biological activities. Some Wnts signal through the canonical Wnt-1/wingless pathway by stabilizing cytoplasmic beta-catenin. By contrast other W
Autor:
Michael Kühl, Petra Pandur, Diane C. Slusarski, Randall T. Moon, Jeffrey R. Miller, Laird C. Sheldahl
Publikováno v:
The Journal of Cell Biology
Wnt ligands and Frizzled (Fz) receptors have been shown to activate multiple intracellular signaling pathways. Activation of the Wnt–β-catenin pathway has been described in greatest detail, but it has been reported that Wnts and Fzs also activate
Publikováno v:
The Journal of biological chemistry. 275(17)
Wnt ligands working through Frizzled receptors have a differential ability to stimulate release of intracellular calcium (Ca(2+)) and activation of protein kinase C (PKC). Since targets of this Ca(2+) release could play a role in Wnt signaling, we fi
Publikováno v:
Endocrine (1355008X); Apr2006, Vol. 29 Issue 2, p199-208, 10p