Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Laila C. Roisman"'
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionVitamin C (L-ascorbic acid) plays a vital role in human physiology, serving as both an antioxidant and a cofactor in enzymatic reactions. High-dose intravenous Vitamin C can achieve significantly elevated plasma concentrations, potentiall
Externí odkaz:
https://doaj.org/article/21016b4645174a3c952f99780a3d2657
Autor:
Rachel Shemesh, Smadar Laufer-Geva, Yaara Gorzalczany, Alaa Anoze, Ronit Sagi-Eisenberg, Nir Peled, Laila C. Roisman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Mast cells (MCs) are immune cells that play roles in both normal and abnormal processes. They have been linked to tumor progression in several types of cancer, including non-small cell lung cancer (NSCLC). However, the exact role of MCs in N
Externí odkaz:
https://doaj.org/article/680af982f413426ba63aaf6c7dba3c2d
Radiological artificial intelligence - predicting personalized immunotherapy outcomes in lung cancer
Autor:
Laila C. Roisman, Waleed Kian, Alaa Anoze, Vered Fuchs, Maria Spector, Roee Steiner, Levi Kassel, Gilad Rechnitzer, Iris Fried, Nir Peled, Naama R. Bogot
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-7 (2023)
Abstract Personalized medicine has revolutionized approaches to treatment in the field of lung cancer by enabling therapies to be specific to each patient. However, physicians encounter an immense number of challenges in providing the optimal treatme
Externí odkaz:
https://doaj.org/article/6d563b82163448ea9a8961b9c94c5800
Autor:
Waleed Kian, Bilal Krayim, Hadel Alsana, Betsy Giles, Ofer Purim, Wafeek Alguayn, Farouq Alguayn, Nir Peled, Laila C. Roisman
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Lung cancer is the most common cancer-related cause of death worldwide, most of which are non-small cell lung cancers (NSCLC). Epidermal growth factor receptor (EGFR) mutations are common drivers of NSCLC. Treatment plans for NSCLC, specifically aden
Externí odkaz:
https://doaj.org/article/6868af2f25d84da6a90cf2804406ca92
Autor:
Waleed Kian, Petros Christopoulos, Areen A. Remilah, Esther Levison, Elizabeth Dudnik, Walid Shalata, Bilal Krayim, Ranin Marei, Alexander Yakobson, Martin Faehling, Dolev Kahala, Inbal Sara Granot, Dina Levitas, Nir Peled, Laila C. Roisman
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundNon-small cell lung cancer (NSCLC) harboring EGFR exon 20 insertions (EGFRex20ins) is relatively resistant to the existing EGFR tyrosine kinase inhibitors (TKIs). Mobocertinib is a novel TKI that selectively targets EGFRex20ins and has demo
Externí odkaz:
https://doaj.org/article/252716256e0d40cdb3abfed9b15d6132
Autor:
Or Sehayek, Waleed Kian, Amir Onn, Ronen Stoff, Hadas Gantz Sorotsky, Melanie Zemel, Jair Bar, Yulia Dudnik, Hovav Nechushtan, Yakir Rottenberg, Lior Soussan-Gutman, Addie Dvir, Laila C. Roisman, Nir Peled
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PurposeMolecular profiling is crucial in naïve non-small cell lung cancer (NSCLC). While tissue-based analysis is challenged by turnaround time and scarcity of tissue, there is increasing demand for liquid biopsy. We aimed to analyze the use of upfr
Externí odkaz:
https://doaj.org/article/85362ec588224779aae89838b8d19a1d
Autor:
Alexander Yakobson, Wafeek Alguayn, Walid Shalata, Daniel Levin, Tawfeek A. Kian, Amir Korngreen, Rachel Gibbs, Mahmuod A. Salah, Benzion Samueli, Konstantin Lavrenkov, Laila C. Roisman, Yulia Dudnik, Nir Peled, Yael Refaely, Waleed Kian
Publikováno v:
Case Reports in Oncology, Vol 14, Iss 1, Pp 309-317 (2021)
Epithelioid hemangioma (EH) and epithelioid hemangioendothelioma (EHE) are both rare vascular tumors. EH tumors are often benign while EHE tumors have moderate malignant potential. Here, we present three unique cases at Soroka Medical Center, two fea
Externí odkaz:
https://doaj.org/article/ac549e73e2b54014b4ccb914a0d25dfc
Autor:
Muhammed Iraqi, Priyanka Bolel, Rhitajit Sarkar, Baisali Bhattacharya, Muhammad Abu Ahmad, Avishay Edri, Laila C. Roisman, Moshe Elkabets, Walid Shalata, Nir Peled, Angel Porgador
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14054 (2022)
Lung cancer cells in the tumor microenvironment facilitate immune evasion that leads to failure of conventional chemotherapies, despite provisionally decided on the genetic diagnosis of patients in a clinical setup. The current study follows three lu
Externí odkaz:
https://doaj.org/article/249f0a43fe804b55809a5a0dfe4339ae
Autor:
Jonathan W. Riess, Shaila Rahman, Waleed Kian, Claire Edgerly, Andreas M. Heilmann, Russell Madison, Shakti H. Ramkissoon, Shai Shlomi Klaitman, Jon H. Chung, Sally E. Trabucco, Dexter X. Jin, Brian M. Alexander, Samuel J. Klempner, Lee A. Albacker, Garrett M. Frampton, Laila C. Roisman, Vincent A. Miller, Jeffrey S. Ross, Alexa B. Schrock, Jeffrey P. Gregg, Nir Peled, Ethan S. Sokol, Siraj M. Ali
Publikováno v:
Translational Oncology, Vol 14, Iss 10, Pp 101184- (2021)
Background: The translocation t(15:19) produces the oncogenic BRD4-NUT fusion which is pathognomonic for NUT carcinoma (NC), which is a rare, but extremely aggressive solid tumor. Comprehensive genomic profiling (CGP) by hybrid-capture based next gen
Externí odkaz:
https://doaj.org/article/f78f81cbdd204e1789f4f2191a1fc032
Autor:
Waleed Kian, MD, Dina Levitas, MD, Wafeek Alguayn, MD, Walid Shalata, MD, Adam A. Sharb, MD, Daniel Levin, MD, Laila C. Roisman, PhD, Margarita Tokar, MD, Nir Peled, MD, PhD, FCCP, Alexander Yakobson, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 1, Iss 1, Pp 100002- (2020)
Externí odkaz:
https://doaj.org/article/ad8ff2ac570b49da9dde15eaf28326b0