Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Laila A, Bishara"'
Autor:
Laila A. Bishara, Samah W. Awwad, Feras E. Machour, Tirza Bidany-Mizrahi, Nabieh Ayoub, Enas R Abu-Zhayia, Stefan Meinke, Rami I. Aqeilan, Florian Heyd
Publikováno v:
Nucleic Acids Research
Nucleic Acid Research
Nucleic Acid Research
RNA-binding proteins regulate mRNA processing and translation and are often aberrantly expressed in cancer. The RNA-binding motif protein 6, RBM6, is a known alternative splicing factor that harbors tumor suppressor activity and is frequently mutated
SummaryPreviously, we showed that CDYL1 is recruited to DNA double-strand breaks (DSBs) to promote homology-directed repair (HDR) and foster transcriptional silencing. Yet, how CDYL1 elicits DSB-induced silencing is not fully understood. Here, we sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0516b43ff9194177d6dea4e23ac1c321
https://doi.org/10.1101/2021.05.31.446417
https://doi.org/10.1101/2021.05.31.446417
Autor:
Enas R, Abu-Zhayia, Laila A, Bishara, Feras E, Machour, Alma Sophia, Barisaac, Bella M, Ben-Oz, Nabieh, Ayoub
Publikováno v:
Molecular Cell. 82:1940-1955.e7
Previously, we showed that CDYL1 is recruited to DNA double-strand breaks (DSBs) to promote homologous recombination (HR) repair and foster transcriptional silencing. However, how CDYL1 elicits DSB-induced silencing is not fully understood. Here, we
Publikováno v:
DNA Repair. 97:103025
The negative elongation factor (NELF) is a four-subunit protein complex (NELF-E, NELF-A, NELF-B and NELF-C/D) that negatively regulates transcription elongation of RNA polymerase II (Pol II). Interestingly, upregulation of NELF-E subunit promotes hep
Publikováno v:
Canadian Journal of Diabetes. 37:S34