Nanoformulated Recombinant Human Myelin Basic Protein and Rituximab Modulate Neuronal Perturbations in Experimental Autoimmune Encephalomyelitis in Mice

Autor: Saad MA, Eissa NM, Ahmed MA, ElMeshad AN, Laible G, Attia AS, Al-Ghobashy MA, Abdelsalam RM, Al-Shorbagy MY

Publikováno v: International Journal of Nanomedicine, Vol Volume 17, Pp 3967-3987 (2022)

Muhammed A Saad,1,2 Noha M Eissa,2 Mohammed A Ahmed,3 Aliaa N ElMeshad,3,4 Götz Laible,5– 7 Ahmed S Attia,8 Medhat A Al-Ghobashy,9,10 Rania M Abdelsalam,1,2 Muhammad Y Al-Shorbagy1,11 1Department of Pharmacology and Toxicology, Faculty of Pharmacy

Externí odkaz: https://doaj.org/article/82b770e954594d7194f89cf705dfd027

Production of light-coloured, low heat-absorbing Holstein Friesian cattle by precise embryo-mediated genome editing.

Autor: Wei J; Animal Biotechnology, Ruakura Research Centre, AgResearch, Hamilton, New Zealand., Brophy B; Animal Biotechnology, Ruakura Research Centre, AgResearch, Hamilton, New Zealand., Cole SA; Animal Biotechnology, Ruakura Research Centre, AgResearch, Hamilton, New Zealand., Leath S; Animal Biotechnology, Ruakura Research Centre, AgResearch, Hamilton, New Zealand., Oback B; Animal Biotechnology, Ruakura Research Centre, AgResearch, Hamilton, New Zealand; and School of Sciences, University of Waikato, Hamilton, New Zealand; and Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Boch J; Institute of Plant Genetics, Leibniz Universität Hannover, Hannover, Germany., Wells DN; Animal Biotechnology, Ruakura Research Centre, AgResearch, Hamilton, New Zealand., Laible G; Animal Biotechnology, Ruakura Research Centre, AgResearch, Hamilton, New Zealand; and Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand.

Publikováno v: Reproduction, fertility, and development [Reprod Fertil Dev] 2023 Dec; Vol. 36 (2), pp. 112-123.

Additional file 1 of Holstein Friesian dairy cattle edited for diluted coat color as a potential adaptation to climate change

Autor: Laible, G., Cole, S.-A., Brophy, B., Wei, J., Leath, S., Jivanji, S., Littlejohn, M. D., Wells, D. N.

Additional file 1: Table S1. PCR primer, probe, gRNA and repair template sequences used to characterise the PMEL locus and white spotting genes. Table S2. Genotype for major-effect QTL associated with white spotting. Fig. S1. Target site sequence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3167e4857cbcf39b60f03fbdcc824cf8

Cytoplasmic Injection of Zygotes to Genome Edit Naturally Occurring Sequence Variants Into Bovine Embryos.

Autor: Wei J; Animal Biotechnology, Ruakura Research Centre, AgResearch Ltd, Hamilton, New Zealand., Brophy B; Animal Biotechnology, Ruakura Research Centre, AgResearch Ltd, Hamilton, New Zealand., Cole SA; Animal Biotechnology, Ruakura Research Centre, AgResearch Ltd, Hamilton, New Zealand., Moormann J; Institute of Plant Genetics, Leibniz Universität Hannover, Hannover, Germany., Boch J; Institute of Plant Genetics, Leibniz Universität Hannover, Hannover, Germany., Laible G; Animal Biotechnology, Ruakura Research Centre, AgResearch Ltd, Hamilton, New Zealand.; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand.

Publikováno v: Frontiers in genetics [Front Genet] 2022 Jul 11; Vol. 13, pp. 925913. Date of Electronic Publication: 2022 Jul 11 (Print Publication: 2022).

The genomes of precision edited cloned calves show no evidence for off-target events or increased de novo mutagenesis.

Autor: Jivanji S; School of Agriculture and Environment, Massey University, Palmerston North, New Zealand. swati.jivanji.1@uni.massey.ac.nz., Harland C; Livestock Improvement Corporation, Newstead, New Zealand., Cole S; AgResearch, Ruakura Research Centre, Hamilton, New Zealand., Brophy B; AgResearch, Ruakura Research Centre, Hamilton, New Zealand., Garrick D; School of Agriculture and Environment, Massey University, Palmerston North, New Zealand., Snell R; School of Biological Sciences, University of Auckland, Auckland, New Zealand., Littlejohn M; School of Agriculture and Environment, Massey University, Palmerston North, New Zealand.; Livestock Improvement Corporation, Newstead, New Zealand., Laible G; AgResearch, Ruakura Research Centre, Hamilton, New Zealand.; School of Medical Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.

Publikováno v: BMC genomics [BMC Genomics] 2021 Jun 17; Vol. 22 (1), pp. 457. Date of Electronic Publication: 2021 Jun 17.