Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laia Sadeghi"'
Autor:
Laia Sadeghi, Magali Merrien, Magnus Bjorkholm, Birgitta Sander, Hans-Erik Claesson, Anthony Wright
Publikováno v:
HemaSphere, Vol 7, p e5045724 (2023)
Externí odkaz:
https://doaj.org/article/563512d25a6b4b6e9d43d21cc7678203
Autor:
Laia Sadeghi, Anthony P. H. Wright
Publikováno v:
Cells, Vol 12, Iss 15, p 2010 (2023)
Multiple signaling pathways facilitate the survival and drug resistance of malignant B-cells by regulating their migration and adhesion to microenvironmental niches. NF-κB pathways are commonly dysregulated in mantle cell lymphoma (MCL), but the exa
Externí odkaz:
https://doaj.org/article/2676e7f2696241219e2d7a0091f7d8c7
Autor:
Laia Sadeghi, Anthony P. Wright
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6247 (2021)
Lymphocyte migration to and sequestration in specific microenvironments plays a crucial role in their differentiation and survival. Lymphocyte trafficking and homing are tightly regulated by signaling pathways and is mediated by cytokines, chemokines
Externí odkaz:
https://doaj.org/article/f0bac65e4dfc4506962c97476dbf9f16
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 8, p e1002163 (2011)
Epigenetic regulation consists of a multitude of different modifications that determine active and inactive states of chromatin. Conditions such as cell differentiation or exposure to environmental stress require concerted changes in gene expression.
Externí odkaz:
https://doaj.org/article/6e007d9f107140c78e1103c52707aa8b
The transcription factor MYC regulates the expression of a vast number of genes and is implicated in various human malignancies, for which it’s deregulation by genomic events such as translocation or amplification can be either disease-defining or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89314690ba0c723bc64f8f7a148b8638
https://doi.org/10.1101/2020.07.13.200238
https://doi.org/10.1101/2020.07.13.200238
Autor:
Laia Sadeghi, Anthony P. H. Wright, Gustav Arvidsson, Magali Merrien, André Görgens, Birgitta Sander, C. I. Edvard Smith, Agata M. Wasik
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1143, p 1143 (2020)
Cancers, Vol 12, Iss 1143, p 1143 (2020)
Interactions between lymphoma cells and stromal cells play a key role in promoting tumor survival and development of drug resistance. We identified differences in key signaling pathways between the JeKo-1 and REC-1 mantle cell lymphoma (MCL) cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e0b9d6f3c1d09877eb8f8396fae60b
https://doi.org/10.1101/2020.03.06.980235
https://doi.org/10.1101/2020.03.06.980235
Autor:
Klas Strååt, Magali Merrien, Anders Österborg, Anthony P. H. Wright, Laia Sadeghi, Magnus Björkholm, Chuanyou Xia, Birgitta Sander, Dawei Xu, Hans-Erik Claesson
Publikováno v:
Prostaglandins & Other Lipid Mediators. 156:106575
Human B-lymphocytes express 5-lipoxygenase (5-LOX) and 5-LOX activating protein (FLAP) and can convert arachidonic acid to leukotriene B4. Mantle cell lymphoma (MCL) cells contain similar amounts of 5-LOX as human neutrophils but the function and mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1e31840b9b4b4bbfcc9a95b3288a07
https://doi.org/10.1016/j.prostaglandins.2021.106575
https://doi.org/10.1016/j.prostaglandins.2021.106575
Publikováno v:
EMBO Reports
The maintenance of open and repressed chromatin states is crucial for the regulation of gene expression. To study the genes involved in maintaining chromatin states, we generated a random mutant library in Schizosaccharomyces pombe and monitored the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc01b4fd08b811c08ca6f047e23d83e
https://doi.org/10.15252/embr.201541214
https://doi.org/10.15252/embr.201541214
Publikováno v:
Nature structuralmolecular biology. 21(3)
Functional centromeres are essential for proper cell division. Centromeres are established largely by epigenetic processes resulting in incorporation of the histone H3 variant CENP-A. Here, we demonstrate the direct involvement of H2B monoubiquitinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7b6474d55c0113ff47e494131dea61
https://pubmed.ncbi.nlm.nih.gov/24531659
https://pubmed.ncbi.nlm.nih.gov/24531659