Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Laia Cabellos"'
Autor:
Estefania Cuesta-Borràs, Cándida Salvans, Oriol Arqués, Irene Chicote, Lorena Ramírez, Laia Cabellos, Jordi Martínez-Quintanilla, Alex Mur-Espinosa, Alejandro García-Álvarez, Jorge Hernando, Juan Ramón Tejedor, Oriol Mirallas, Elena Élez, Mario F. Fraga, Josep Tabernero, Paolo Nuciforo, Jaume Capdevila, Héctor G. Palmer, Isabel Puig
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112927- (2023)
Summary: Tumor relapse is linked to rapid chemoresistance and represents a bottleneck for cancer therapy success. Engagement of a reduced proliferation state is a non-mutational mechanism exploited by cancer cells to bypass therapy-induced cell death
Externí odkaz:
https://doaj.org/article/ffddfe7e78e24b41b3ac5cdc84b543de
Autor:
Josep M. Llovet, Scott L. Friedman, Myron Schwartz, Vincenzo Mazzaferro, Jordi Bruix, Stephen C. Ward, Swan Thung, Jordi Barretina, Hung-Wen Tsai, Philippa Newell, Beatriz Minguez, Augusto Villanueva, Yujin Hoshida, Sara Toffanin, Laia Cabellos, Radoslav Savic, Clara Alsinet, Anja Lachenmayer
PDF file, 10.8MB, Supplementary Table 1: Clinical characteristics of human hepatocellular carcinoma samples. Supplementary Table 2: Clinical Characteristics of 5 public HCC datasets. Supplementary Table 3: Wnt-pathway mRNA list: 210 Wnt-related genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7bc1a4563b714df9e6c108a776a695
https://doi.org/10.1158/1078-0432.22444386.v1
https://doi.org/10.1158/1078-0432.22444386.v1
Autor:
Josep M. Llovet, Scott L. Friedman, Myron Schwartz, Vincenzo Mazzaferro, Jordi Bruix, Stephen C. Ward, Swan Thung, Jordi Barretina, Hung-Wen Tsai, Philippa Newell, Beatriz Minguez, Augusto Villanueva, Yujin Hoshida, Sara Toffanin, Laia Cabellos, Radoslav Savic, Clara Alsinet, Anja Lachenmayer
Purpose: Hepatocellular carcinoma (HCC) is a heterogeneous cancer with active Wnt signaling. Underlying biologic mechanisms remain unclear and no drug targeting this pathway has been approved to date. We aimed to characterize Wnt-pathway aberrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6c6da9153f44eaadd81eed98dc49a7
https://doi.org/10.1158/1078-0432.c.6520146
https://doi.org/10.1158/1078-0432.c.6520146
Autor:
Bram Herpers, Berina Eppink, Mark I. James, Carme Cortina, Adrià Cañellas-Socias, Sylvia F. Boj, Xavier Hernando-Momblona, Dominik Glodzik, Rob C. Roovers, Marc van de Wetering, Carina Bartelink-Clements, Vanessa Zondag-van der Zande, Jara García Mateos, Kuan Yan, Lucia Salinaro, Abdul Basmeleh, Szabolcs Fatrai, David Maussang, Jeroen J. Lammerts van Bueren, Irene Chicote, Garazi Serna, Laia Cabellos, Lorena Ramírez, Paolo Nuciforo, Ramon Salazar, Cristina Santos, Alberto Villanueva, Camille Stephan-Otto Attolini, Elena Sancho, Hector G. Palmer, Josep Tabernero, Michael R. Stratton, John de Kruif, Ton Logtenberg, Hans Clevers, Leo S. Price, Robert G. J. Vries, Eduard Batlle, Mark Throsby
Publikováno v:
Nature cancer, 3(4), 418-436
Patient-derived organoids (PDOs) recapitulate tumor architecture, contain cancer stem cells and have predictive value supporting personalized medicine. Here we describe a large-scale functional screen of dual-targeting bispecific antibodies (bAbs) on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6787d32a1a24821ce4603c0851f3e6
https://pure.knaw.nl/portal/en/publications/06b7bea9-adb4-44dc-9013-631489b16e6a
https://pure.knaw.nl/portal/en/publications/06b7bea9-adb4-44dc-9013-631489b16e6a
Autor:
Maria Isabel Fiel, Carlos Villacorta-Martin, Giancarlo Castellano, Miguel Torres-Martin, Augusto Villanueva, Wei Q. Leow, Agrin Moeini, Judit Peix, Roger Esteban-Fabró, Carla Montironi, Manel Solé, Swan N. Thung, Leonardo Rodriguez-Carunchio, Daniela Sia, Ismail Labgaa, Miho Maeda, Myron Schwartz, Josep Fuster, Lewis R. Roberts, Parissa Tabrizian, Robert Montal, Josep M. Llovet, Beatriz Minguez, Sasan Roayaie, Laia Bassaganyas, Christine Sempoux, Laia Cabellos, Timothy M. Pawlik, Roser Pinyol
Publikováno v:
J Hepatol
BACKGROUND AND AIMS: Cholangiocarcinoma (CCA), a deadly malignancy of the bile ducts, can be classified on the basis of its anatomical location into either intrahepatic (iCCA) or extrahepatic (eCCA), each with different pathogenesis and clinical mana
Autor:
Ramón Vilana, Carlos Martinez, Joana Ferrer Fábrega, Juan Carlos García-Valdecasas, Romina Pena, Laia Cabellos, Carolina Gonzalez-Abós, Aranzazu Varona-Bosque, José Fuster Obregón, Beatriz Revilla-Nuin, Rocío García-Pérez
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) has been suggested as a potential therapy for extensive bilobar liver tumors, although in some circumstances this technique may induce tumor progression, a fact still
Autor:
Maria Isabel Fiel, Daniela Sia, Agrin Moeini, Laia Cabellos, Ke Hao, Josep M. Llovet, Swan N. Thung, Zhongyang Zhang, Sara Torrecilla, Andrew N. Harrington, Augusto Villanueva, Genis Camprecios, Helena Cornella, Sander Florman, Wei Qiang Leow, Myron Schwartz, Milind Mahajan, Laia Bassaganyas
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Journal of Hepatology
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Journal of Hepatology
Background & Aims According to the clonal model of tumor evolution, trunk alterations arise at early stages and are ubiquitous. Through the characterization of early stages of hepatocarcinogenesis, we aimed to identify trunk alterations in hepatocell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6553b4462dad6f090822fbe2c854fecd
http://hdl.handle.net/2445/120662
http://hdl.handle.net/2445/120662
Autor:
Timothy M. Pawlik, A. Villanueva, Daniela Sia, Parissa Tabrizian, Agrin Moeini, Miho Maeda, Wei Qiang Leow, S. Thung, Roser Pinyol, M.I. Fiel, Ismail Labgaa, M. Schwartz, Robert Montal, L. Roberts, Beatriz Minguez, Carla Montironi, Laia Bassaganyas, Manel Solé, Laia Cabellos, Judit Peix, Sasan Roayaie, Josep M. Llovet
Publikováno v:
Journal of Hepatology. 68:S2-S3
Autor:
Roger Esteban-Fabró, Laia Bassaganyas, Sara Torrecilla, Agrin Moeini, Sebastià Franch-Expósito, Maria Vila-Casadesús, Ferran Nadeu, Daniela Sia, Itziar Salaverria, Laia Cabellos, Roser Pinyol, Jordi Camps, Vicenzo Mazzaferro, Josep M Llovet
Publikováno v:
Cancer Research. 79:3095-3095
Introduction: Aneuploidy is a cancer hallmark that includes broad somatic copy-number alterations (SCNAs), being whole chromosome- or arm-level events, or smaller focal SCNAs. Pan-cancer studies suggest that tumor broad and focal SCNAs are linked to
Autor:
Itziar Salaverria, Ferran Nadeu, Roger Esteban-Fabró, Maria Vila-Casadesús, Laia Cabellos, Jordi Camps, Daniela Sia, Agrin Moeini, Sara Torrecilla, Josep M. Llovet, Sebastià Franch-Expósito, Roser Pinyol, Laia Bassaganyas, Vincenzo Mazzaferro
Publikováno v:
Journal of Hepatology. 70:e30