Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Laia Acarin"'
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72083 (2013)
During postnatal development, microglia, the resident innate immune cells of the central nervous system are constantly monitoring the brain parenchyma, cleaning the cell debris, the synaptic contacts overproduced and also maintaining the brain homeos
Externí odkaz:
https://doaj.org/article/919e954bfa46448cb0d0bb1f4ee22f9a
Publikováno v:
Neurology Research International, Vol 2012 (2012)
Understanding the evolution of neonatal hypoxic/ischemic is essential for novel neuroprotective approaches. We describe the neuropathology and glial/inflammatory response, from 3 hours to 100 days, after carotid occlusion and hypoxia (8% O2, 55 minut
Externí odkaz:
https://doaj.org/article/2da86df0a14b4e3d9a38fbd6da2784ed
Publikováno v:
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
PLoS ONE, Vol 8, Iss 8, p e72083 (2013)
PLoS ONE
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
PLoS ONE, Vol 8, Iss 8, p e72083 (2013)
PLoS ONE
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
During postnatal development, microglia, the resident innate immune cells of the central nervous system are constantly monitoring the brain parenchyma, cleaning the cell debris, the synaptic contacts overproduced and also maintaining the brain homeos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3821496fab092c043381391adcb29c1f
http://hdl.handle.net/2072/403504
http://hdl.handle.net/2072/403504
Publikováno v:
The Journal of Comparative Neurology. 520:2657-2675
The CD200/CD200R inhibitory immune ligand-receptor system regulates microglial activation/quiescence in adult brain. Here, we investigated CD200/CD200R at different stages of postnatal development, when microglial maturation takes place. We character
Autor:
Maria del Mar Castillo-Ruiz, Oscar Campuzano, Laia Acarin, Berta González, Bernardo Castellano
Publikováno v:
Experimental Gerontology. 46:723-730
Brain aging is associated to several morphological and functional alterations that influence the evolution and outcome of CNS damage. Acute brain injury such as an excitotoxic insult induces initial tissue damage followed by associated inflammation a
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 68:391-403
Inflammation is an important determinant of the severity and outcome of central nervous system injury. The endogenous anti-inflammatory cytokine interleukin-10 (IL-10) is upregulated in the injured adult central nervous system where it controls and t
Publikováno v:
Neuroscience. 153:108-119
Following immature excitotoxic brain damage, distinct patterns of caspase activation have been described in neurons and glial cells. Neuronal cells show activation of the mitochondrial apoptosis pathway, caspase-3 cleavage and apoptotic cell death, w
Autor:
Hugo Peluffo, Pau Gonzalez, Berta González, Josep Saura, Anna Arís, Laia Acarin, A. Villaverde, Bernardo Castellano
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
[Objective]: Integrin binding to extracellular matrix ligands, including those presenting RGD motifs, modulate diverse cellular processes. In the brain, many endogenous RGD-containing molecules are induced after damage. Previously, the gene therapy v
Publikováno v:
Journal of Neuroscience Research. 85:3545-3556
Although cleaved caspase-3 is known to be involved in apoptotic cell death mechanisms in neurons, it can also be involved in a nonapoptotic role in astrocytes after postnatal excitotoxic injury. Here we evaluate participation of upstream pathways act
Autor:
Hugo Peluffo, Anna Arís, Laia Acarin, Berta González, Bernardo Castellano, Antonio Villaverde
Publikováno v:
Human Gene Therapy. 14:1215-1223
Successful introduction of therapeutic genes into the central nervous system (CNS) requires the further development of efficient transfer vehicles that avoid viral vector-dependent adverse reactions while maintaining high transfection efficiency. The