Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lai-Xing Wang"'
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 8, Iss 1, Pp 1540001-1-1540001-8 (2015)
Photodynamic therapy (PDT) represents a promising method for treatment of cancerous tumors. The chemical and physical properties of used photosensitizer (PS) play key roles in the treatment efficacy. In this study, a novel PS, 5,10,15,20-tetrakis((5-
Externí odkaz:
https://doaj.org/article/1e8a5dae5b294659a4fc60a80180a3ed
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 8, Iss 1, Pp 1540003-1-1540003-11 (2015)
In this study, a novel photosensitizer meso-tetra (3-pyrrolidinomethyl-4-methoxyphenyl) chlorin (TPMC) was reported. It displays a characteristic long wavelength absorption peak at 656 nm and it shows a singlet oxygen quantum yield of 0.48. After lig
Externí odkaz:
https://doaj.org/article/10edcfe263f14a99986a2f6b1a08bb85
Autor:
Lai-Xing Wang, Hui Jin, Bao Leilei, Chen Ting, Yan Qiu, Faiza Sajjad, Yi-Jia Yan, Han Yiping, Zhi-Long Chen
Publikováno v:
Photodiagnosis and photodynamic therapy. 37
BACKGROUND A green emission up-conversion carbon-based polymer dots (CPDs) owned excellent photophysical properties and good solubility. While most of the photosensitizers (PS) are hydrophobic thus limits the application of PSs in biomedicine. Herein
Autor:
Dan-Ye Chen, Mi Wang, Han Yiping, Xiao-Feng Wu, Lai-Xing Wang, Ying-Hua Gao, Yi-Jia Yan, Wei Zhu, Zhi-Long Chen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:2784-2788
Three novel 173-dicarboxylethyl-pyropheophorbide-a amide derivatives as photosensitizers for photodynamic therapy (PDT) were synthesized from pyropheophorbide-a (Ppa). Their photophysical and photochemical properties, intracellular localization, phot
Autor:
Li-Jun Zhang, Donal F. O'Shea, Zhi-Long Chen, Jian-Yue Huang, Jian-Hong Li, Lai-Xing Wang, Jian-Wei Li
Publikováno v:
Tumor Biology. 36:6839-6847
Chlorin derivatives are promising photosensitive agents for photodynamic therapy (PDT) of tumors. The aim of the current study is to investigate the PDT therapeutic effects of a novel chlorin-based photosensitizer, meso-tetra[3-(N,N-diethyl)aminometh
Autor:
Wei, Zhu, Lai-Xing, Wang, Dan-Ye, Chen, Ying-Hua, Gao, Yi-Jia, Yan, Xiao-Feng, Wu, Mi, Wang, Yi-Ping, Han, Zhi-Long, Chen
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(16)
Three novel 17
Publikováno v:
Academic Journal of Second Military Medical University. 30:1152-1154
Autor:
xiaohu hu, Guosheng Han, Liu Jianmin, Wen-Yuan Zhao, Yue Zhijian, Lai-xing Wang, Zhao Rui, Xiaoping Zhou, Li Yanan
Glioblastoma is a highly aggressive malignant disease with notable resistance to chemotherapy. In this study, we found that leptin receptor (ObR)-positive glioblastoma cells were resistant to temozolomide (TMZ), and TMZ-resistant cells exhibited high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e012c9451b73bf26fe70ea0bb0bb5a31
https://europepmc.org/articles/PMC3905075/
https://europepmc.org/articles/PMC3905075/
Publikováno v:
Experimental and therapeutic medicine. 2(4)
Although previous studies have shown that γ-secretase inhibitors significantly suppress tumor growth via anti-angiogenesis, the mechanism involved in the regulation of tumor angiogenesis by γ-secretase inhibitors has not been clearly understood. Th
Autor:
Yuhui Zhang, Jianmin Liu, Jing Yingying, Lai-Xing Wang, Jinchuan Liang, Zhi-Jian Yue, Guosheng Han, Xiaowu Hu
Publikováno v:
Regulatory peptides. 163(1-3)
Previous studies demonstrate that leptin has an osteogenic differentiation effect on bone marrow mesenchymal stem cells (MSCs). However, the effect of adenovirus-mediated leptin on MSCs differentiation has not been reported. To explore the mechanism,