Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lai-Jiang Chen"'
Publikováno v:
International Journal of Hypertension, Vol 2015 (2015)
The renin-angiotensin aldosterone system (RAAS) plays a pivotal role in the development of hypertension. Angiotensin converting enzyme 2 (ACE2), which primarily metabolises angiotensin (Ang) II to generate the beneficial heptapeptide Ang-(1-7), serve
Externí odkaz:
https://doaj.org/article/9abdb3c5b7364d43b3316e184e41d1f5
Autor:
Qing Chang, Hai-Yan Jin, Dingliang Zhu, Zhen-Zhou Zhang, Bei Song, Lai-Jiang Chen, Ran Xu, Jiu-Chang Zhong, Ying-Le Xu, Gavin Y. Oudit, Huimin Yu
Publikováno v:
Peptides. 79:49-57
Angiotensin-converting enzyme 2 (ACE2) has been shown to prevent atherosclerotic lesions and renal inflammation. However, little was elucidated upon the effects and mechanisms of ACE2 in atherosclerotic kidney fibrosis progression. Here, we examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6407ef033c37b6328b94a5d53fb2c318
https://doi.org/10.1016/j.peptides.2016.03.008
https://doi.org/10.1016/j.peptides.2016.03.008
Autor:
Hai-Yan Jin1,2, Lai-Jiang Chen1,3, Zhen-Zhou Zhang1,3, Ying-Le Xu1, Bei Song1, Ran Xu1, Oudit, Gavin Y.4, Ping-Jin Gao1,3, Ding-Liang Zhu1,2,3, Jiu-Chang Zhong1,2,3 jiuchangzhong@aliyun.com
Publikováno v:
Journal of Translational Medicine. Aug2015, Vol. 13 Issue 1, p1-16. 16p.
Autor:
Dong-Rui Chen, Jiu-Chang Zhong, Zhen-Zhou Zhang, Huimin Yu, Shujie Guo, Gavin Y. Oudit, Ying-Le Xu, Yan Zhang, Lai-Jiang Chen, Dingliang Zhu, Bei Song, Ran Xu, Qing Chang
Publikováno v:
Peptides. 86
Apelin has been proved to be a critical mediator of vascular function and homeostasis. Here, we investigated roles of Apelin in aortic remodeling and fibrosis in rats with transverse aortic constriction (TAC). Male Sprague-Dawley rats were subjected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405c917300fc58f5f3a0611ebce42dee
https://pubmed.ncbi.nlm.nih.gov/27773659
https://pubmed.ncbi.nlm.nih.gov/27773659
Autor:
Zhen-Zhou Zhang, Qing Chang, Ran Xu, Ying-Le Xu, Dingliang Zhu, Lai-Jiang Chen, Pingjin Gao, Jiu-Chang Zhong
Publikováno v:
Journal of the American College of Cardiology. 66(16)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c12437b958be417ddffc4ebb757585
Autor:
Dingliang Zhu, Bei Song, Jiu-Chang Zhong, Pingjin Gao, Zhen-Zhou Zhang, Hai-Yan Jin, Gavin Y. Oudit, Ying-Le Xu, Ran Xu, Lai-Jiang Chen
Publikováno v:
Journal of Translational Medicine
Background The renin-angiotensin system (RAS) has been implicated in atherosclerotic lesions and progression to chronic kidney diseases. We examined regulatory roles of angiotensin-converting enzyme 2 (ACE2) in the apolipoprotein E (ApoE) knockout (K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0fad30ab0fc26eed96ca70ee59f471
https://doi.org/10.1186/s12967-015-0616-8
https://doi.org/10.1186/s12967-015-0616-8
Publikováno v:
International Journal of Hypertension
International Journal of Hypertension, Vol 2015 (2015)
International Journal of Hypertension, Vol 2015 (2015)
The renin-angiotensin aldosterone system (RAAS) plays a pivotal role in the development of hypertension. Angiotensin converting enzyme 2 (ACE2), which primarily metabolises angiotensin (Ang) II to generate the beneficial heptapeptide Ang-(1-7), serve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7d29e4d06dfc4aa2bba87aa2f1edbc
https://pubmed.ncbi.nlm.nih.gov/25815211
https://pubmed.ncbi.nlm.nih.gov/25815211
Autor:
Lai-Jiang Chen, Ying-Le Xu, Ran Xu, Bei Song, Hai-Yan Jin, Qing Chang, Gavin Y. Oudit, Ji-Guang Wang, Pingjin Gao, Zhen-Zhou Zhang, Shujie Guo, Jiu-Chang Zhong
Publikováno v:
Journal of Hypertension. 34:e403-e404
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15f7589de61a9c557d4a74bbba2bb51b
https://doi.org/10.1097/01.hjh.0000501036.54612.96
https://doi.org/10.1097/01.hjh.0000501036.54612.96
Autor:
Ying-Le Xu, Lai-Jiang Chen, Pingjin Gao, Zhen-Zhou Zhang, Jiu-Chang Zhong, Dingliang Zhu, Dong-Rui Chen, Bei Song, Gavin Y. Oudit
Publikováno v:
Journal of the American College of Cardiology. 64:C6-C7
Apelin is a second catalytic substrate for angiotensin-converting enzyme 2 (ACE2). Apelin and its cognate receptor APJ are essential for diverse biological processes. However, the function of Apelin signaling in the vasculature remains to be identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db2f1353d971f7f6a7a4a3f0a7f2236
https://doi.org/10.1016/j.jacc.2014.06.040
https://doi.org/10.1016/j.jacc.2014.06.040
Autor:
Hai-Yan Jin, Jiu-Chang Zhong, Lai-Jiang Chen, Josef M. Penninger, Huimin Yu, Xi-Yong Yu, Gavin Y. Oudit, Pingjin Gao, Zhen-Zhou Zhang, Bei Song, Ying-Le Xu
Publikováno v:
Journal of the American College of Cardiology. 64:C1
Inhibition of the renin-angiotensin system (RAS) has lead to important pharmacological tools to treat atherosclerosis and other cardiovascular diseases. Angiotensin-converting enzyme 2 (ACE2) has emerged as a central negative regulator of RAS by degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae14afa0da0bb8178424c4edd2defd5
https://doi.org/10.1016/j.jacc.2014.06.017
https://doi.org/10.1016/j.jacc.2014.06.017