Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lai Ping Yaw"'
Autor:
Zu Ye, Chee Ping Ng, Haidong Liu, Qimei Bao, Shengfeng Xu, Dan Zu, Yanhua He, Yixing Huang, Omer Al-Aidaroos, Abdul Qader, Ke Guo, Jie Li, Lai Ping Yaw, Qiancheng Xiong, Min Thura, Weihui Zheng, Fenghui Guan, Xiangdong Cheng, Yin Shi, Qi Zeng
Publikováno v:
Theranostics; 2024, Vol. 14 Issue 9, p3423-3438, 16p
Autor:
Hidayat Lokman, Huck-Hui Ng, Audrey Tze Ting Khoo, Wei-Yi Ong, Junghyun Jo, Grace Lim, Hoang Dai Tran, Seung-Jae Lee, Weonjin Yu, Lin Yang, Lai Ping Yaw, Ya Yin Chang, Jessica Jiaxin Xie, Kah-Leong Lim, Bin Xiao, Eng-King Tan, Tzuen Yih Saw, Byung Chul Jung, Alfred Xuyang Sun, Hyunsoo Shawn Je
Publikováno v:
Annals of neurology. 90(3)
Objective: We utilized human midbrain-like organoids (hMLOs) generated from human pluripotent stem cells carrying glucocerebrosidase gene (GBA1) and α-synuclein (α-syn; SNCA) perturbations to investigate genotype-to-phenotype relationships in Parki
Autor:
Ka Man Yu, Yun-Shen Chan, Huck-Hui Ng, John Soon Yew Lim, Lai Ping Yaw, Chaiyaboot Ariyachet, Deniz Demircioğlu, Chwee Tat Koe, Yee Siang Lim, Einsi Lynn Soe, Hongqing Liang, Kevin Andrew Uy Gonzales, Nur Halisah Binte Jumat, Yock Young Dan, Iwona Szczerbinska, Shu Hui Koh, Zhiping Lu, Cheng Peow Tan, Asim Shabbir, Graham D. Wright, Wei-Quan Tng, Muhammad Nadzim Bin Ramli
Publikováno v:
Gastroenterology. 159:1471-1486.e12
Background & Aims There are few in vitro models for studying the 3-dimensional interactions among different liver cell types during organogenesis or disease development. We aimed to generate hepatic organoids that comprise different parenchymal liver
Autor:
Jianyong Han, Paul Robson, Yuin-Han Loh, Mikael Huss, Ping Yuan, Yuriy L. Orlov, Huck-Hui Ng, Lai-Ping Yaw, Bing Lim, Guoji Guo
Publikováno v:
Genes & Development. 23:2507-2520
The histone H3 Lys 9 (H3K9) methyltransferase Eset is an epigenetic regulator critical for the development of the inner cell mass (ICM). Although ICM-derived embryonic stem (ES) cells are normally unable to contribute to the trophectoderm (TE) in bla
Autor:
Sookja K. Chung, Margaret C. S. Tsang, Stephen S.M. Chung, Maggie C. Y. Ho, Victor K L Hung, Amy C. Y. Lo, Maggie K.L. Fung, Lai Ping Yaw, Ann Y.S. Chen
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 25:998-1011
Stroke patients have increased levels of endothelin-1 (ET-1), a strong vasoconstrictor, in their plasma or cerebrospinal fluid. Previously, we showed high level of ET-1 mRNA expression in astrocytes after hypoxia/ischemia. It is unclear whether the c
Publikováno v:
Journal of Biological Chemistry. 274:2851-2857
The large gene family encoding the regulators of G protein signaling (RGS) proteins has been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. Several studies have shown that the RGS p
Autor:
Petra Kraus, Vibhor Kumar, Masafumi Muratani, Kun Xue, Shyam Prabhakar, Jia-Chi Yeo, Lai-Ping Yaw, Thomas Lufkin, Huck-Hui Ng, Jia-Hui Ng
Publikováno v:
Developmental cell. 24(3)
SummaryThe limited number of in vivo germ cells poses an impediment to genome-wide studies. Here, we applied a small-scale chromatin immunoprecipitation sequencing (ChIP-seq) method on purified mouse fetal germ cells to generate genome-wide maps of f
We reveal a set of divergent octamer elements in Drosophila melanogaster (dm) core histone gene promoters. These elements recruit transcription factor POU-domain protein in D. melanogaster 1 (Pdm-1), which along with co-activator dmOct-1 coactivator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88959a3802c614bb238ff31d3fdaa4dc
https://europepmc.org/articles/PMC2838325/
https://europepmc.org/articles/PMC2838325/
Autor:
Yun-Shen Chan, Huck-Hui Ng, Jia-Hui Ng, Jianming Jiang, Bo Feng, Petra Kraus, Lai-Ping Yaw, Vinsensius B. Vega, Thomas Lufkin, Jian-Chien Dominic Heng, Bing Lim, Valere Cacheux-Rataboul, Weiwei Zhang, Yuin-Han Loh, Jianyong Han
Publikováno v:
Nature cell biology. 11(2)
The dominant effect of transcription factors in imparting expanded potency is best exemplified by the reprogramming of fibroblasts to pluripotent cells using retrovirus-mediated transduction of defined transcription factors. In the murine system, Oct